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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-b/BMP Signaling at the Primary Cilium

Authors:
Mönnich M, Borgeskov L, Breslin L, Jakobsen L, Rogowski M, Doganli C, Schrøder JM, Mogensen JB, Blinkenkjær L, Harder LM, Lundberg E, Geimer S, Christensen ST, Andersen JS, Larsen LA, Pedersen LB
Citation:
Cell Rep. 2018;22(10):2584-92. doi:10.1016/j.celrep.2018.02.043
Epub:
Not Epub
Abstract:
The centrosome is the main microtubule-organizing center in animal cells and comprises a mother and daughter centriole...
Link:
http://www.cell.com/cell-reports/fulltext/S2211-1247(18)30224-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mönnich M, Borgeskov L, Breslin L, Jakobsen L, Rogowski M, Doganli C, Schrøder JM, Mogensen JB, Blinkenkjær L, Harder LM, Lundberg E, Geimer S, Christensen ST, Andersen JS, Larsen LA, Pedersen LB. CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-b/BMP Signaling at the Primary Cilium. Cell Rep. 2018;22(10):2584-92. doi:10.1016/j.celrep.2018.02.043.

zHSF1 modulates zper2 expression in zebrafish embryos

Authors:
Mennetrier L, Lopez T, Pruvot B, Yousfi N, Armant O, Hazhaz H, Lhuissiez V, Garrido C, Chluba J
Citation:
Chronobiol Int. 2018 Mar 6:1-8. doi: 10.1080/07420528.2018.1441855. [Epub ahead of print]
Epub:
Yes
Abstract:
HSF1 is a transcription factor that plays a key role in circadian resetting by temperature. We have used zebrafish embryos to...
Link:
https://www.tandfonline.com/doi/full/10.1080/07420528.2018.1441855
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mennetrier L, Lopez T, Pruvot B, Yousfi N, Armant O, Hazhaz H, Lhuissiez V, Garrido C, Chluba J. zHSF1 modulates zper2 expression in zebrafish embryos. Chronobiol Int. 2018 Mar 6:1-8. doi: 10.1080/07420528.2018.1441855. [Epub ahead of print].

Anti-apoptotic effects of IGF-I on mortality and dysmorphogenesis in tbx5-deficient zebrafish embryos

Authors:
Tsai TC, Shih CC, Chien HP, Yang AH, Lu JK, Lu JH
Citation:
BMC Dev Biol. 2018 Mar 5;18(1):5. doi: 10.1186/s12861-017-0161-1
Epub:
Not Epub
Abstract:
BACKGROUND: Tbx5 deficiency in zebrafish causes several abnormal phenotypes of the heart and pectoral fins. It has been...
Link:
https://bmcdevbiol.biomedcentral.com/articles/10.1186/s12861-017-0161-1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tsai TC, Shih CC, Chien HP, Yang AH, Lu JK, Lu JH. Anti-apoptotic effects of IGF-I on mortality and dysmorphogenesis in tbx5-deficient zebrafish embryos. BMC Dev Biol. 2018 Mar 5;18(1):5. doi: 10.1186/s12861-017-0161-1.

A screen for deeply conserved non-coding GWAS SNPs uncovers a MIR-9-2 functional mutation associated to retinal vasculature defects in human

Authors:
Madelaine R, Notwell JH, Skariah G, Halluin C, Chen CC, Bejerano G, Mourrain P
Citation:
Nucl Acids Res. 2018;[Epub ahead of print] doi:10.1093/nar/gky166
Epub:
Yes
Abstract:
Thousands of human disease-associated single nucleotide polymorphisms (SNPs) lie in the non-coding genome, but only a handful...
Link:
https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gky166/4922459
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Madelaine R, Notwell JH, Skariah G, Halluin C, Chen CC, Bejerano G, Mourrain P. A screen for deeply conserved non-coding GWAS SNPs uncovers a MIR-9-2 functional mutation associated to retinal vasculature defects in human. Nucl Acids Res. 2018;[Epub ahead of print] doi:10.1093/nar/gky166.

Sea urchin histamine receptor 1 regulates programmed cell death in larval Strongylocentrotus purpuratus

Authors:
Lutek K, Dhaliwal RS, Van Raay TJ, Heyland A
Citation:
Sci Rep. 2018;8:4002 doi:10.1038/s41598-018-22397-4
Epub:
Not Epub
Abstract:
Settlement is a rapid process in many marine invertebrate species, transitioning a planktonic larva into a benthic juvenile. In...
Link:
https://www.nature.com/articles/s41598-018-22397-4
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Lutek K, Dhaliwal RS, Van Raay TJ, Heyland A. Sea urchin histamine receptor 1 regulates programmed cell death in larval Strongylocentrotus purpuratus. Sci Rep. 2018;8:4002 doi:10.1038/s41598-018-22397-4.

An interaction between myosin-10 and the cell cycle regulator Wee1 links spindle dynamics to mitotic progression in epithelia

Authors:
Sandquist JC, Larson ME, Woolner S, Ding Z, Bement WM
Citation:
J Cell Biol. 2018 Jan 10. pii: jcb.201708072. doi: 10.1083/jcb.201708072. [Epub ahead of print]
Epub:
Yes
Abstract:
Anaphase in epithelia typically does not ensue until after spindles have achieved a characteristic position and orientation,...
Link:
http://jcb.rupress.org/content/early/2018/01/09/jcb.201708072
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Sandquist JC, Larson ME, Woolner S, Ding Z, Bement WM. An interaction between myosin-10 and the cell cycle regulator Wee1 links spindle dynamics to mitotic progression in epithelia. J Cell Biol. 2018 Jan 10. pii: jcb.201708072. doi: 10.1083/jcb.201708072. [Epub ahead of print].

Metalloproteinase Adamts16 Is Required for Proper Closure of the Optic Fissure

Authors:
Cao M, Ouyang J, Guo J, Lin S, Chen S
Citation:
Invest Ophthalmol Vis Sci. 2018;59:1167-77. doi:10.1167/iovs.17-22827
Epub:
Not Epub
Abstract:
Purpose: Coloboma is a sight-threatening congenital eye disease caused by a failure in optic fissure (OF) closure. The aim of...
Link:
http://iovs.arvojournals.org/article.aspx?articleid=2674330
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cao M, Ouyang J, Guo J, Lin S, Chen S. Metalloproteinase Adamts16 Is Required for Proper Closure of the Optic Fissure. Invest Ophthalmol Vis Sci. 2018;59:1167-77. doi:10.1167/iovs.17-22827 .

Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders

Authors:
Calo E, Gu B, Bowen ME, Aryan F, Zalc A, Liang J, Flynn RA, Swigut T, Chang HY, Attardi LD, Wysocka J
Citation:
Nature. 2018 Feb 1;554(7690):112-117. doi: 10.1038/nature25449. Epub 2018 Jan 24
Epub:
Not Epub
Abstract:
Many craniofacial disorders are caused by heterozygous mutations in general regulators of housekeeping cellular functions such...
Link:
https://www.nature.com/articles/nature25449
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus, zebrafish
Citation Extract:
Calo E, Gu B, Bowen ME, Aryan F, Zalc A, Liang J, Flynn RA, Swigut T, Chang HY, Attardi LD, Wysocka J. Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders. Nature. 2018 Feb 1;554(7690):112-117. doi: 10.1038/nature25449. Epub 2018 Jan 24.

The transcription factor Dach1 is essential for podocyte function

Authors:
Endlich N, Kliewe F, Kindt F, Schmidt K, Kotb AM, Artelt N, Lindenmeyer MT, Cohen CD, Döring F, Kuss AW, Amann K, Moeller MJ, Kabgani N, Blumenthal A, Endlich K
Citation:
J Cell Mol Med. 2018 Mar 2. doi: 10.1111/jcmm.13544. [Epub ahead of print]
Epub:
Yes
Abstract:
Dedifferentiation and loss of podocytes are the major cause of chronic kidney disease. Dach1, a transcription factor that is...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/jcmm.13544/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Endlich N, Kliewe F, Kindt F, Schmidt K, Kotb AM, Artelt N, Lindenmeyer MT, Cohen CD, Döring F, Kuss AW, Amann K, Moeller MJ, Kabgani N, Blumenthal A, Endlich K. The transcription factor Dach1 is essential for podocyte function. J Cell Mol Med. 2018 Mar 2. doi: 10.1111/jcmm.13544. [Epub ahead of print].

Pharmacological analysis of zebrafish lphn3.1 morphant larvae suggests that saturated dopaminergic signaling could underlie the ADHD-like locomotor hyperactivity

Authors:
Lange M, Froc C, Grunwald H, Norton WHJ, Bally-Cuif L
Citation:
Prog Neuropsychopharmacol Biol Psychiatry. 2018 Feb 26. pii: S0278-5846(17)30733-9. doi: 10.1016/j.pnpbp.2018.02.010. [Epub ahead of print]
Epub:
Yes
Abstract:
Polymorphisms in the gene coding for the adhesion G-protein coupled receptor LPHN3 are a risk factor for attention-deficit/...
Link:
https://www.sciencedirect.com/science/article/pii/S0278584617307339
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lange M, Froc C, Grunwald H, Norton WHJ, Bally-Cuif L. Pharmacological analysis of zebrafish lphn3.1 morphant larvae suggests that saturated dopaminergic signaling could underlie the ADHD-like locomotor hyperactivity. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Feb 26. pii: S0278-5846(17)30733-9. doi: 10.1016/j.pnpbp.2018.02.010. [Epub ahead of print].

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