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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Myelination of Neuronal Cell Bodies when Myelin Supply Exceeds Axonal Demand

Authors:
Almeida RG, Pan S, Cole KLH, Williamson JM, Early JJ, Czopka T, Klingseisen A, Chan JR, Lyons DA
Citation:
Curr Biol. 2018;[Epub ahead of print]. doi:10.1016/j.cub.2018.02.068
Epub:
Yes
Abstract:
The correct targeting of myelin is essential for nervous system formation and function. Oligodendrocytes in the CNS myelinate...
Link:
http://www.cell.com/current-biology/fulltext/S0960-9822(18)30254-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Almeida RG, Pan S, Cole KLH, Williamson JM, Early JJ, Czopka T, Klingseisen A, Chan JR, Lyons DA. Myelination of Neuronal Cell Bodies when Myelin Supply Exceeds Axonal Demand. Curr Biol. 2018;[Epub ahead of print]. doi:10.1016/j.cub.2018.02.068.

Terminal Uridylyltransferases Execute Programmed Clearance of Maternal Transcriptome in Vertebrate Embryos

Authors:
Chang H, Yeo Y, Kim J-g, Kim H, Lim J, Lee M, Kim HH, Ohk J, Jeon H-Y, Lee H, Jung H, Kim K-W, Kim VN
Citation:
Molec Cell. 2018;70(1):72-82.e7. doi:10.1016/j.molcel.2018.03.004
Epub:
Not Epub
Abstract:
During the maternal-to-zygotic transition (MZT), maternal RNAs are actively degraded and replaced by newly synthesized zygotic...
Link:
http://www.cell.com/molecular-cell/fulltext/S1097-2765(18)30185-0
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Chang H, Yeo Y, Kim J-g, Kim H, Lim J, Lee M, Kim HH, Ohk J, Jeon H-Y, Lee H, Jung H, Kim K-W, Kim VN. Terminal Uridylyltransferases Execute Programmed Clearance of Maternal Transcriptome in Vertebrate Embryos. Molec Cell. 2018;70(1):72-82.e7. doi:10.1016/j.molcel.2018.03.004.

Xenopus ADAM19 regulates Wnt signaling and neural crest specification by stabilizing ADAM13

Authors:
Li J, Perfetto M, Neuner R, Bahudhanapati H, Christian L, Mathavan K, Bridges LC, Alfandari D, Wei S
Citation:
Development. 2018 Mar 14. pii: dev.158154. doi: 10.1242/dev.158154. [Epub ahead of print]
Epub:
Yes
Abstract:
During vertebrate gastrulation, canonical Wnt signaling induces the formation of neural plate border (NPB). Wnt is also thought...
Link:
http://dev.biologists.org/content/145/7/dev158154
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Li J, Perfetto M, Neuner R, Bahudhanapati H, Christian L, Mathavan K, Bridges LC, Alfandari D, Wei S. Xenopus ADAM19 regulates Wnt signaling and neural crest specification by stabilizing ADAM13. Development. 2018 Mar 14. pii: dev.158154. doi: 10.1242/dev.158154. [Epub ahead of print].

Gon4l regulates notochord boundary formation and cell polarity underlying axis extension by repressing adhesion genes

Authors:
Williams MLK, Sawada A, Budine T, Yin C, Gontarz P, Solnica-Krezel L
Citation:
Nat Comm. 2018;9:1319. doi:10.1038/s41467-018-03715-w
Epub:
Not Epub
Abstract:
Anteroposterior (AP) axis extension during gastrulation requires embryonic patterning and morphogenesis to be spatiotemporally...
Link:
https://www.nature.com/articles/s41467-018-03715-w
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Williams MLK, Sawada A, Budine T, Yin C, Gontarz P, Solnica-Krezel L. Gon4l regulates notochord boundary formation and cell polarity underlying axis extension by repressing adhesion genes. Nat Comm. 2018;9:1319. doi:10.1038/s41467-018-03715-w.

Requirement of zebrafish pcdh10a and pcdh10b in melanocyte precursor migration

Authors:
Williams JS, Hsu JY, Rossi CC, Artinger KB
Citation:
Dev Biol. 2018 Mar 28. pii: S0012-1606(17)30939-9. doi: 10.1016/j.ydbio.2018.03.022. [Epub ahead of print]
Epub:
Yes
Abstract:
Melanocytes derive from neural crest cells, which are a highly migratory population of cells that play an important role in...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160617309399
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Williams JS, Hsu JY, Rossi CC, Artinger KB. Requirement of zebrafish pcdh10a and pcdh10b in melanocyte precursor migration. Dev Biol. 2018 Mar 28. pii: S0012-1606(17)30939-9. doi: 10.1016/j.ydbio.2018.03.022. [Epub ahead of print].

MARCKS phosphorylation by PKC strongly impairs cell polarity in the chick neural plate

Authors:
Aparicio G, Arruti C, Zolessi FR
Citation:
Genesis. 2018 Mar 30. doi: 10.1002/dvg.23104. [Epub ahead of print]
Epub:
Yes
Abstract:
Neurulation involves a complex coordination of cellular movements that are in great part based on the modulation of the actin...
Link:
https://onlinelibrary.wiley.com/doi/pdf/10.1002/dvg.23104
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Aparicio G, Arruti C, Zolessi FR. MARCKS phosphorylation by PKC strongly impairs cell polarity in the chick neural plate. Genesis. 2018 Mar 30. doi: 10.1002/dvg.23104. [Epub ahead of print].

Identification of Variants in RET and IHH Pathway Members in a Large Family With History of Hirschsprung Disease

Authors:
Sribudiani Y, Chauhan RK, Alves MM, Petrova L, Brosens E, Harrison C, Wabbersen T, de Graaf BM, Rügenbrink T, Burzynski G, Brouwer RWW, IJcken WFJV, Maas SM, de Klein A, Osinga J, Eggen BJL, Burns AJ, Brooks AS, Shepherd IT, Hofstra RMW
Citation:
Gastroenterology. 2018 Mar 27. pii: S0016-5085(18)30341-X. doi: 10.1053/j.gastro.2018.03.034. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND & AIMS: Hirschsprung disease (HSCR) is an inherited congenital disorder characterized by absence of enteric...
Link:
http://www.gastrojournal.org/article/S0016-5085(18)30341-X/fulltext
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sribudiani Y, Chauhan RK, Alves MM, Petrova L, Brosens E, Harrison C, Wabbersen T, de Graaf BM, Rügenbrink T, Burzynski G, Brouwer RWW, IJcken WFJV, Maas SM, de Klein A, Osinga J, Eggen BJL, Burns AJ, Brooks AS, Shepherd IT, Hofstra RMW. Identification of Variants in RET and IHH Pathway Members in a Large Family With History of Hirschsprung Disease. Gastroenterology. 2018 Mar 27. pii: S0016-5085(18)30341-X. doi: 10.1053/j.gastro.2018.03.034. [Epub ahead of print].

Hypomethylation of GRHL3 gene is associated with the occurrence of neural tube defects

Authors:
Tian T, Wang L, Shen Y, Zhang B, Finnell RH, Ren A
Citation:
Epigenomics. 2018 Mar 28. doi: 10.2217/epi-2018-0016. [Epub ahead of print]
Epub:
Yes
Abstract:
AIM: To investigate the relationship between GRHL3 methylation and the etiology of neural tube defects (NTDs). MATERIALS...
Link:
https://www.futuremedicine.com/doi/abs/10.2217/epi-2018-0016
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tian T, Wang L, Shen Y, Zhang B, Finnell RH, Ren A. Hypomethylation of GRHL3 gene is associated with the occurrence of neural tube defects. Epigenomics. 2018 Mar 28. doi: 10.2217/epi-2018-0016. [Epub ahead of print].

An APOO Pseudogene on Chromosome 5q is Associated with LDL-C Levels

Authors:
Montasser ME, O'Hare EA, Wang X, Howard AD, McFarland R, Perry JA, Ryan KA, Rice K, Jaquish CE, Shuldiner AR, Miller M, Mitchell BD, Zaghloul NA, Chang Y-PC
Citation:
Circulation. 2018;[Epub ahead of print] doi:10.1161/CIRCULATIONAHA.118.034016
Epub:
Not Epub
Abstract:
Background: Elevated levels of low-density lipoprotein cholesterol (LDL-C) are a major risk factor for CVD via its contribution...
Link:
http://circ.ahajournals.org/content/early/2018/03/27/CIRCULATIONAHA.118.034016
Organism or Cell Type:
zebrafish
Citation Extract:
Montasser ME, O'Hare EA, Wang X, Howard AD, McFarland R, Perry JA, Ryan KA, Rice K, Jaquish CE, Shuldiner AR, Miller M, Mitchell BD, Zaghloul NA, Chang Y-PC. An APOO Pseudogene on Chromosome 5q is Associated with LDL-C Levels. Circulation. 2018;[Epub ahead of print] doi:10.1161/CIRCULATIONAHA.118.034016.

miR-206 is required for changes in cell adhesion that drive muscle cell morphogenesis in Xenopus laevis

Authors:
Vergara HM, Ramirez J, Rosing T, Nave C, Blandino R, Saw D, Saraf P, Piexoto G, Coombes C, Adams M, Domingo CR
Citation:
Dev Biol. 2018;[Epub ahead of print] doi:10.1016/j.ydbio.2018.03.021
Epub:
Yes
Abstract:
MicroRNAs (miRNAs) are highly conserved small non-coding RNA molecules that post-transcriptionally regulate gene expression in...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160617307285
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Vergara HM, Ramirez J, Rosing T, Nave C, Blandino R, Saw D, Saraf P, Piexoto G, Coombes C, Adams M, Domingo CR. miR-206 is required for changes in cell adhesion that drive muscle cell morphogenesis in Xenopus laevis. Dev Biol. 2018;[Epub ahead of print] doi:10.1016/j.ydbio.2018.03.021.

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