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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Leishmania donovani Subverts Host Immune Response by Epigenetic Reprogramming of Macrophage M(Lipopolysaccharides + IFN-γ)/M(IL-10) Polarization
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Citation:
J Immunol. 2020;204 (10) 2762-2778. doi: 10.4049/jimmunol.1900251. [Epub ahead of print] Epub:
Not Epub Abstract:
Reciprocal changes in histone lysine methylation/demethylation of M(LPS + IFN-γ)/M(IL-10) genes is one of the factors that... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Parmar N, Chandrakar P, Kar S. Leishmania donovani Subverts Host Immune Response by Epigenetic Reprogramming of Macrophage M(Lipopolysaccharides + IFN-γ)/M(IL-10) Polarization. J Immunol. 2020;204 (10) 2762-2778. doi: 10.4049/jimmunol.1900251. [Epub ahead of print]. |
Rab5c-mediated endocytic trafficking regulates hematopoietic stem and progenitor cell development via Notch and AKT signaling
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Citation:
PLoS Biol. 2020;18(4):e3000696. doi:10.1371/journal.pbio.3000696 Epub:
Not Epub Abstract:
It is well known that various developmental signals play diverse roles in hematopoietic stem and progenitor cell (HSPC)... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Heng J, Lv P, Zhang Y, Cheng X, Wang L, Ma D, Liu F. Rab5c-mediated endocytic trafficking regulates hematopoietic stem and progenitor cell development via Notch and AKT signaling. PLoS Biol. 2020;18(4):e3000696. doi:10.1371/journal.pbio.3000696. |
Pathological mechanism and antisense oligonucleotide-mediated rescue of a non-coding variant suppressing factor 9 RNA biogenesis leading to hemophilia B
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Citation:
PLoS Genet. 2020;16(4):e1008690. doi:10.1371/journal.pgen.1008690 Epub:
Not Epub Abstract:
Loss-of-function mutations in the human coagulation factor 9 (F9) gene lead to hemophilia B. Here, we dissected the... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HeLa Citation Extract: Krooss S, Werwitzke S, Kopp J, Rovai A, Varnholt D, Wachs AS, Goyenvalle A, Aarstma-Rus A, Ott M, Tiede A, Langemeier J, Bohne J. Pathological mechanism and antisense oligonucleotide-mediated rescue of a non-coding variant suppressing factor 9 RNA biogenesis leading to hemophilia B. PLoS Genet. 2020;16(4):e1008690. doi:10.1371/journal.pgen.1008690. |
The cohesin release factor Wapl interacts with Bub3 to govern SAC activity in female meiosis I
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Citation:
Sci Adv. 2020;6(15):eaax3969. doi:10.1126/sciadv.aax3969 Epub:
Not Epub Abstract:
During mitotic prophase, cohesins are removed from chromosome arms by Wapl to ensure faithful sister chromatid separation.... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Zhou C, Miao Y, Cui Z, ShiYang X, Zhang Y, Xiong B. The cohesin release factor Wapl interacts with Bub3 to govern SAC activity in female meiosis I. Sci Adv. 2020;6(15):eaax3969. doi:10.1126/sciadv.aax3969. |
Piezo1 and outflow tract and aortic valve development
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Citation:
J Molec Cell Cardiol. 2020;[Epub] doi:10.1016/j.yjmcc.2020.03.013 Epub:
Yes Abstract:
Aims: During embryogenesis, the onset of circulatory blood flow generates a variety of hemodynamic forces which reciprocally... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Faucherre A, ou Maati HM, Nasr N, Pinard A, Theron A, Odelin G, Desvignes JP, Salgado D, Collod-Béroud G, Avierinos JF, Lebon G, Zaffran S, Jopling C. Piezo1 and outflow tract and aortic valve development. J Molec Cell Cardiol. 2020;[Epub] doi:10.1016/j.yjmcc.2020.03.013. |
Alternative splicing is a developmental switch for hTERT expression
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.04.02.022087 Epub:
Not Epub Abstract:
High telomerase activity is restricted to the blastocyst stage of embryonic development when telomere length is reset, and is... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HeLa Citation Extract: Penev A, Bazley A, Shen M, Boeke JD, Savage SA, Sfeir A. Alternative splicing is a developmental switch for hTERT expression. bioRxiv. 2020;[preprint] doi:10.1101/2020.04.02.022087. |
A dual role for Axin in establishing the anterior-posterior axis in the early sea urchin embryo
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.04.02.022640 Epub:
Not Epub Abstract:
The activation of Wnt/β-catenin (cWnt) signaling at the future posterior end of early embryos is a highly conserved mechanism... Delivery Method:
microinjection Organism or Cell Type:
Lytechinus variegatus, Strongylocentrotus purpuratus (sea urchins) Citation Extract: Sun S, Peng CFJ, Wang L, Feng H, Wikramanayake AH. A dual role for Axin in establishing the anterior-posterior axis in the early sea urchin embryo. bioRxiv. 2020;[preprint] doi:10.1101/2020.04.02.022640 . |
Trade-off between somatic and germline repair in a vertebrate supports the expensive germ line hypothesis
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Citation:
Proc Natl Acad Sci U S A. 2020 Apr 3. pii: 201918205. doi: 10.1073/pnas.1918205117. [Epub ahead of print] Epub:
Yes Abstract:
The disposable soma theory is a central tenet of the biology of aging where germline immortality comes at the cost of an aging... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen HY, Jolly C, Bublys K, Marcu D, Immler S. Trade-off between somatic and germline repair in a vertebrate supports the expensive germ line hypothesis. Proc Natl Acad Sci U S A. 2020 Apr 3. pii: 201918205. doi: 10.1073/pnas.1918205117. [Epub ahead of print]. |
Distinct Vegfa isoforms control endothelial cell proliferation through PI3 kinase signalling mediated regulation of cdkn1a/p21
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.04.01.018796 Epub:
Not Epub Abstract:
The formation of appropriately patterned blood vessel networks requires endothelial cell migration and proliferation. Signaling... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lange M, Leonard E, Ohnesorge N, Hoffmann D, Rocha S, Benedito R, Siekmann AF. Distinct Vegfa isoforms control endothelial cell proliferation through PI3 kinase signalling mediated regulation of cdkn1a/p21. bioRxiv. 2020;[preprint] doi:10.1101/2020.04.01.018796. |
Chondroitin sulfate proteoglycan 4 regulates zebrafish body axis organization via Wnt/planar cell polarity pathway
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Citation:
PLoS ONE. 2020;15(4):e0230943. doi:10.1371/journal.pone.0230943 Epub:
Not Epub Abstract:
Pericellular and extracellular proteoglycans play an important role in modulating morphogen gradients and signal transductions... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lee Y-H, Kawakami K, HuangFu W-C, Liu I-H. Chondroitin sulfate proteoglycan 4 regulates zebrafish body axis organization via Wnt/planar cell polarity pathway. PLoS ONE. 2020;15(4):e0230943. doi:10.1371/journal.pone.0230943. |