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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Aberrant connexin26 hemichannels underlying keratitis-ichthyosis-deafness syndrome are potently inhibited by mefloquine

Authors:
Levit NA, Sellitto C, Wang HZ, Li L, Srinivas M, Brink PR, White TW
Citation:
J Invest Dermatol. 2015 Apr;135(4):1033-1042. doi: 10.1038/jid.2014.408. Epub 2014 Sep 17
Epub:
Not Epub
Abstract:
Keratitis-ichthyosis-deafness (KID) syndrome is an ectodermal dysplasia caused by dominant mutations of connexin26 (Cx26). Loss...
Link:
https://www.jidonline.org/article/S0022-202X(15)37186-4/fulltext
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Levit NA, Sellitto C, Wang HZ, Li L, Srinivas M, Brink PR, White TW. Aberrant connexin26 hemichannels underlying keratitis-ichthyosis-deafness syndrome are potently inhibited by mefloquine. J Invest Dermatol. 2015 Apr;135(4):1033-1042. doi: 10.1038/jid.2014.408. Epub 2014 Sep 17.

Involvement of zebrafish RIG-I in NF-κB and IFN signaling pathways: insights into functional conservation of RIG-I in antiviral innate immunity

Authors:
Nie L, Zhang YS, Dong WR, Xiang LX, Shao JZ
Citation:
Dev Comp Immunol. 2015 Jan;48(1):95-101. doi: 10.1016/j.dci.2014.09.008. Epub 2014 Oct 5
Epub:
Not Epub
Abstract:
The retinoic acid-inducible gene I (RIG-I) is a critical sensor for host recognition of RNA virus infection and initiation of...
Link:
https://www.sciencedirect.com/science/article/pii/S0145305X14002407
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nie L, Zhang YS, Dong WR, Xiang LX, Shao JZ. Involvement of zebrafish RIG-I in NF-κB and IFN signaling pathways: insights into functional conservation of RIG-I in antiviral innate immunity. Dev Comp Immunol. 2015 Jan;48(1):95-101. doi: 10.1016/j.dci.2014.09.008. Epub 2014 Oct 5.

Early stages of induction of anterior head ectodermal properties in Xenopus embryos are mediated by transcriptional cofactor ldb1

Authors:
Plautz CZ, Zirkle BE, Deshotel MJ, Grainger RM
Citation:
Dev Dyn. 2014 Dec;243(12):1606-18. doi: 10.1002/dvdy.24193. Epub 2014 Oct 18
Epub:
Not Epub
Abstract:
BACKGROUND: Specific molecules involved in early inductive signaling from anterior neural tissue to the placodal ectoderm to...
Link:
https://anatomypubs.onlinelibrary.wiley.com/doi/full/10.1002/dvdy.24193
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Plautz CZ, Zirkle BE, Deshotel MJ, Grainger RM. Early stages of induction of anterior head ectodermal properties in Xenopus embryos are mediated by transcriptional cofactor ldb1. Dev Dyn. 2014 Dec;243(12):1606-18. doi: 10.1002/dvdy.24193. Epub 2014 Oct 18.

Papp-a2 modulates development of cranial cartilage and angiogenesis in zebrafish embryos

Authors:
Kjaer-Sorensen K, Engholm DH, Jepsen MR, Morch MG, Weyer K, Hefting LL, Skov LL, Laursen LS, Oxvig C
Citation:
J Cell Sci. 2014 Dec 1;127(Pt 23):5027-37. doi: 10.1242/jcs.152587. Epub 2014 Sep 18
Epub:
Not Epub
Abstract:
Pregnancy-associated plasma protein A2 (PAPP-A2, also known as pappalysin-2) is a large metalloproteinase that is known to be...
Link:
https://jcs.biologists.org/content/127/23/5027.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kjaer-Sorensen K, Engholm DH, Jepsen MR, Morch MG, Weyer K, Hefting LL, Skov LL, Laursen LS, Oxvig C. Papp-a2 modulates development of cranial cartilage and angiogenesis in zebrafish embryos. J Cell Sci. 2014 Dec 1;127(Pt 23):5027-37. doi: 10.1242/jcs.152587. Epub 2014 Sep 18.

Nodal signaling regulates specification of ascidian peripheral neurons through control of the BMP signal

Authors:
Ohtsuka Y, Matsumoto J, Katsuyama Y, Okamura Y
Citation:
Development. 2014 Oct;141(20):3889-99. doi: 10.1242/dev.110213. Epub 2014 Sep 17
Epub:
Not Epub
Abstract:
The neural crest and neurogenic placodes are thought to be a vertebrate innovation that gives rise to much of the peripheral...
Link:
https://dev.biologists.org/content/141/20/3889.long
Delivery Method:
microinjection
Organism or Cell Type:
Halocynthia roretzi (ascidian)
Citation Extract:
Ohtsuka Y, Matsumoto J, Katsuyama Y, Okamura Y. Nodal signaling regulates specification of ascidian peripheral neurons through control of the BMP signal. Development. 2014 Oct;141(20):3889-99. doi: 10.1242/dev.110213. Epub 2014 Sep 17.

Maternal Vsx1 plays an essential role in regulating prechordal mesendoderm and forebrain formation in zebrafish

Authors:
Xu X, He Y, Sun L, Ma S, Luo C
Citation:
Dev Biol. 2014 Oct 15;394(2):264-76. doi: 10.1016/j.ydbio.2014.08.011. Epub 2014 Aug 21
Epub:
Not Epub
Abstract:
Prechordal mesendoderm (PME) is a derivative of gastrula organizer underlying the anterior neural plate of vertebrate embryos....
Link:
https://www.sciencedirect.com/science/article/pii/S0012160614004023
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xu X, He Y, Sun L, Ma S, Luo C. Maternal Vsx1 plays an essential role in regulating prechordal mesendoderm and forebrain formation in zebrafish. Dev Biol. 2014 Oct 15;394(2):264-76. doi: 10.1016/j.ydbio.2014.08.011. Epub 2014 Aug 21.

Function of Sox2 in ependymal cells of lesioned spinal cords in adult zebrafish

Authors:
Ogai K, Nakatani K, Hisano S, Sugitani K, Koriyama Y, Kato S
Citation:
Neurosci Res. 2014 Nov;88:84-7. doi: 10.1016/j.neures.2014.07.010. Epub 2014 Aug 20
Epub:
Not Epub
Abstract:
The sex-determining region Y-box 2 (Sox2) is related not only to pluripotency, but also to cell proliferation. Zebrafish can...
Link:
https://www.sciencedirect.com/science/article/pii/S0168010214001783
Organism or Cell Type:
zebrafish
Citation Extract:
Ogai K, Nakatani K, Hisano S, Sugitani K, Koriyama Y, Kato S. Function of Sox2 in ependymal cells of lesioned spinal cords in adult zebrafish. Neurosci Res. 2014 Nov;88:84-7. doi: 10.1016/j.neures.2014.07.010. Epub 2014 Aug 20.

Analysis of a novel gene, Sdgc, reveals sex chromosome-dependent differences of medaka germ cells prior to gonad formation

Authors:
Nishimura T, Herpin A, Kimura T, Hara I, Kawasaki T, Nakamura S, Yamamoto Y, Saito TL, Yoshimura J, Morishita S, Tsukahara T, Kobayashi S, Naruse K, Shigenobu S, Sakai N, Schartl M, Tanaka M
Citation:
Development. 2014 Sep;141(17):3363-9. doi: 10.1242/dev.106864. Epub 2014 Jul 30
Epub:
Not Epub
Abstract:
In vertebrates that have been examined to date, the sexual identity of germ cells is determined by the sex of gonadal somatic...
Link:
https://dev.biologists.org/content/141/17/3363.long
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Nishimura T, Herpin A, Kimura T, Hara I, Kawasaki T, Nakamura S, Yamamoto Y, Saito TL, Yoshimura J, Morishita S, Tsukahara T, Kobayashi S, Naruse K, Shigenobu S, Sakai N, Schartl M, Tanaka M. Analysis of a novel gene, Sdgc, reveals sex chromosome-dependent differences of medaka germ cells prior to gonad formation. Development. 2014 Sep;141(17):3363-9. doi: 10.1242/dev.106864. Epub 2014 Jul 30.

Interpretable Deep Learning for De Novo Design of Cell-Penetrating Abiotic Polymers

Authors:
Schissel CK, Mohapatra S, Wolfe JM, Fadzen CM, Bellovoda K, Wu C-L, Wood JA, Malmberg AB, Loas A, Gomez-Bombarelli R, Pentelute BL.
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.04.10.036566
Epub:
Not Epub
Abstract:
There are more amino acid permutations within a 40-residue sequence than atoms on Earth. This vast chemical search space...
Link:
https://www.biorxiv.org/content/10.1101/2020.04.10.036566v1
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: HeLa, human renal proximal tublule epithelial cells, mice
Citation Extract:
Schissel CK, Mohapatra S, Wolfe JM, Fadzen CM, Bellovoda K, Wu C-L, Wood JA, Malmberg AB, Loas A, Gomez-Bombarelli R, Pentelute BL.. Interpretable Deep Learning for De Novo Design of Cell-Penetrating Abiotic Polymers. bioRxiv. 2020;[preprint] doi:10.1101/2020.04.10.036566.

Molecular characterization of SLC24A5 variants and evaluation of Nitisinone treatment efficacy in a zebrafish model of OCA6

Authors:
Yousaf S, Sethna S, Chaudhary MA, Shaikh RS, Riazuddin S, Ahmed ZM
Citation:
Pigment Cell Melanoma Res. 2020 Apr 9. doi: 10.1111/pcmr.12879. [Epub ahead of print]
Epub:
Yes
Abstract:
Skin pigmentation is a highly heterogeneous trait with diverse consequences worldwide. SLC24A5, encoding a potent K+ -dependent...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1111/pcmr.12879
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yousaf S, Sethna S, Chaudhary MA, Shaikh RS, Riazuddin S, Ahmed ZM. Molecular characterization of SLC24A5 variants and evaluation of Nitisinone treatment efficacy in a zebrafish model of OCA6. Pigment Cell Melanoma Res. 2020 Apr 9. doi: 10.1111/pcmr.12879. [Epub ahead of print].

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