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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

The transcription factor six1 inhibits neuronal and promotes hair cell fate in the developing zebrafish (Danio rerio) inner ear

Authors:
Bricaud O, Collazo A
Citation:
J Neurosci. 2006 Oct 11;26(41):10438-51
Epub:
Not Epub
Abstract:
The developmental processes leading to the differentiation of mechanosensory hair cells and statoacoustic ganglion neurons from...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bricaud O, Collazo A. The transcription factor six1 inhibits neuronal and promotes hair cell fate in the developing zebrafish (Danio rerio) inner ear. J Neurosci. 2006 Oct 11;26(41):10438-51.

The zebrafish spiel-ohne-grenzen (spg) gene encodes the POU domain protein Pou2 related to mammalian Oct4 and is essential for formation of the midbrain and hindbrain, and for pre-gastrula morphogenesis

Authors:
Burgess S, Reim G, Chen W, Hopkins N, Brand M
Citation:
Development. 2002 Feb; 129(4):905-916
Epub:
Not Epub
Abstract:
n early embryonic development, the brain is divided into three main regions along the anteroposterior axis: the forebrain,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Burgess S, Reim G, Chen W, Hopkins N, Brand M. The zebrafish spiel-ohne-grenzen (spg) gene encodes the POU domain protein Pou2 related to mammalian Oct4 and is essential for formation of the midbrain and hindbrain, and for pre-gastrula morphogenesis. Development. 2002 Feb; 129(4):905-916.

Transcriptional profiling of endogenous germ layer precursor cells identifies dusp4 as an essential gene in zebrafish endoderm specification

Authors:
Brown JL, Snir M, Noushmehr H, Kirby M, Hong SK, Elkahloun AG, Feldman B
Citation:
Proc Natl Acad Sci U S A. 2008 Aug 21. [Epub ahead of print]
Epub:
Not Epub
Abstract:
A major goal for developmental biologists is to define the behaviors and molecular contents of differentiating cells. We have...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brown JL, Snir M, Noushmehr H, Kirby M, Hong SK, Elkahloun AG, Feldman B. Transcriptional profiling of endogenous germ layer precursor cells identifies dusp4 as an essential gene in zebrafish endoderm specification. Proc Natl Acad Sci U S A. 2008 Aug 21. [Epub ahead of print].

Transdermal delivery of antisense compounds

Authors:
Brand RM, Iversen PL
Citation:
Advances Drug Devel. Reviews. 2000. 44(1): 51-57
Epub:
Not Epub
Abstract:
The potential for using antisense compounds as therapeutic agents has generated great enthusiasm. Strategies for delivery of...
Delivery Method:
transdermal
Organism or Cell Type:
not applicable
Citation Extract:
Brand RM, Iversen PL. Transdermal delivery of antisense compounds. Advances Drug Devel. Reviews. 2000. 44(1): 51-57.

Understanding the role of DISC1 in psychiatric disease and during normal development

Authors:
Brandon NJ, Millar JK, Korth C, Sive H, Singh KK, Sawa A
Citation:
J Neurosci. 2009 Oct 14;29(41):12768-75. Review
Epub:
Not Epub
Abstract:
The biology of schizophrenia is complex with multiple hypotheses (dopamine, glutamate, neurodevelopmental) well supported to...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brandon NJ, Millar JK, Korth C, Sive H, Singh KK, Sawa A. Understanding the role of DISC1 in psychiatric disease and during normal development. J Neurosci. 2009 Oct 14;29(41):12768-75. Review.

Vertebrate-specific glutaredoxin is essential for brain development

Authors:
Bräutigam L, Schütte LD, Godoy JR, Prozorovski T, Gellert M, Hauptmann G, Holmgren A, Lillig CH, Berndt C
Citation:
PNAS. 2011 Dec 20;108(51):20532-7. doi: 10.1073/pnas.1110085108. Epub 2011 Dec 2
Epub:
Not Epub
Abstract:
Cellular functions and survival are dependent on a tightly controlled redox potential. Currently, an increasing amount of data...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bräutigam L, Schütte LD, Godoy JR, Prozorovski T, Gellert M, Hauptmann G, Holmgren A, Lillig CH, Berndt C. Vertebrate-specific glutaredoxin is essential for brain development. PNAS. 2011 Dec 20;108(51):20532-7. doi: 10.1073/pnas.1110085108. Epub 2011 Dec 2.

Waterborne exposure of zebrafish embryos to micromole concentrations of ioxynil and diethylstilbestrol disrupts thyrocyte development

Authors:
Campinho MA, Power DM
Citation:
Aquat Toxicol. 2013 Jun 22;140-141C:279-287. doi: 10.1016/j.aquatox.2013.06.014. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The herbicide ioxynil (IOX) and synthetic estrogen diethylstilbestrol (DES) are common aquatic contaminants with an endocrine...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Campinho MA, Power DM. Waterborne exposure of zebrafish embryos to micromole concentrations of ioxynil and diethylstilbestrol disrupts thyrocyte development. Aquat Toxicol. 2013 Jun 22;140-141C:279-287. doi: 10.1016/j.aquatox.2013.06.014. [Epub ahead of print].

Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor

Authors:
Buechling T, Bartscherer K, Ohkawara B, Chaudhary V, Spirohn K, Niehrs C, Boutros M
Citation:
Curr Biol. 2010 Jul 27;20(14):1263-8. doi: 10.1016/j.cub.2010.05.028. Epub 2010 Jun 24
Epub:
Not Epub
Abstract:
Wnt/Wg signaling pathways are of key importance during development and disease. Canonical and noncanonical Wnt/Frizzled (Fz)...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Buechling T, Bartscherer K, Ohkawara B, Chaudhary V, Spirohn K, Niehrs C, Boutros M. Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor. Curr Biol. 2010 Jul 27;20(14):1263-8. doi: 10.1016/j.cub.2010.05.028. Epub 2010 Jun 24.

Wtip and Vangl2 are required for mitotic spindle orientation and cloaca morphogenesis

Authors:
Bubenshchikova E, Ichimura K, Fukuyo Y, Powell R, Hsu C, Morrical SO, Sedor JR, Sakai T, Obara T
Citation:
Bio Open. 2012;[Advance Online Publication] doi:10.1242/bio.20121016
Epub:
Not Epub
Abstract:
Defects in cilia and basal bodies function are linked to ciliopathies, which result in kidney cyst formation. Recently, cell...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bubenshchikova E, Ichimura K, Fukuyo Y, Powell R, Hsu C, Morrical SO, Sedor JR, Sakai T, Obara T. Wtip and Vangl2 are required for mitotic spindle orientation and cloaca morphogenesis. Bio Open. 2012;[Advance Online Publication] doi:10.1242/bio.20121016.

Xenopus laevis insulin receptor substrate IRS-1 is important for eye development

Authors:
Bugner V, Aurhammer T, Kühl M
Citation:
Dev Dyn. 2011 May 13. doi: 10.1002/dvdy.22659. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Extracellular signal transduction into cells through ligand-activated receptor tyrosine kinases, such as insulin-like growth...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bugner V, Aurhammer T, Kühl M. Xenopus laevis insulin receptor substrate IRS-1 is important for eye development. Dev Dyn. 2011 May 13. doi: 10.1002/dvdy.22659. [Epub ahead of print].

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