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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

A zebrafish model of intrahepatic cholangiocarcinoma by dual expression of hepatitis B virus X and hepatitis C virus core protein in liver

Authors:
Liu W, Chen JR, Hsu CH, Li YH, Chen YM, Lin CY, Huang SJ, Chang ZK, Chen YC, Lin CH, Gong HY, Lin CC, Kawakami K, Wu JL
Citation:
Hepatology. 2012 Dec;56(6):2268-76. doi: 10.1002/hep.25914. PMID: 22729936
Epub:
Not Epub
Abstract:
The mechanisms that mediate the initiation and development of intrahepatic cholangiocarcinoma (ICC) associated with hepatitis B...
Organism or Cell Type:
zebrafish
Citation Extract:
Liu W, Chen JR, Hsu CH, Li YH, Chen YM, Lin CY, Huang SJ, Chang ZK, Chen YC, Lin CH, Gong HY, Lin CC, Kawakami K, Wu JL. A zebrafish model of intrahepatic cholangiocarcinoma by dual expression of hepatitis B virus X and hepatitis C virus core protein in liver. Hepatology. 2012 Dec;56(6):2268-76. doi: 10.1002/hep.25914. PMID: 22729936.

Amino acid variations resulting in functional and nonfunctional zebrafish P2X(1) and P2X (5.1) receptors

Authors:
Low SE, Kuwada JY, Hume RI
Citation:
Purinergic Signal. 2008 Dec;4(4):383-92. Epub 2008 Oct 11
Epub:
Not Epub
Abstract:
Several zebrafish P2X receptors (zP2X(1), zP2X(2), and zP2X(5.1)) have been reported to produce little or no current although...
Organism or Cell Type:
zebrafish
Citation Extract:
Low SE, Kuwada JY, Hume RI. Amino acid variations resulting in functional and nonfunctional zebrafish P2X(1) and P2X (5.1) receptors. Purinergic Signal. 2008 Dec;4(4):383-92. Epub 2008 Oct 11.

Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration

Authors:
Love NR, Chen Y, Ishibashi S, Kritsiligkou P, Lea R, Koh Y, Gallop JL, Dorey K, Amaya E
Citation:
Nat Cell Biol. 2013;[Epub ahead of print] doi:/10.1038/ncb2659
Epub:
Not Epub
Abstract:
Understanding the molecular mechanisms that promote successful tissue regeneration is critical for continued advancements in...
Organism or Cell Type:
Xenopus
Citation Extract:
Love NR, Chen Y, Ishibashi S, Kritsiligkou P, Lea R, Koh Y, Gallop JL, Dorey K, Amaya E. Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration. Nat Cell Biol. 2013;[Epub ahead of print] doi:/10.1038/ncb2659.

An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin

Authors:
Lo Sardo V, Zuccato C, Gaudenzi G, Vitali B, Ramos C, Tartari M, Myre MA, Walker JA, Pistocchi A, Conti L, Valenza M, Drung B, Schmidt B, Gusella J, Zeitlin S, Cotelli F, Cattaneo E
Citation:
Nat Neurosci.2012 May;15(5):713-21.
Epub:
Not Epub
Abstract:
The Huntington's disease gene product, huntingtin, is indispensable for neural tube formation, but its role is obscure. We...
Organism or Cell Type:
zebrafish
Citation Extract:
Lo Sardo V, Zuccato C, Gaudenzi G, Vitali B, Ramos C, Tartari M, Myre MA, Walker JA, Pistocchi A, Conti L, Valenza M, Drung B, Schmidt B, Gusella J, Zeitlin S, Cotelli F, Cattaneo E. An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin. Nat Neurosci.2012 May;15(5):713-21..

Araf kinase antagonizes Nodal-Smad2 activity in mesendoderm development by directly phosphorylating the Smad2 linker region

Authors:
Liu X, Xiong C, Jia S, Zhang Y, Chen Y-G, Wang Q, Meng A
Citation:
Nat Commun. 2013;[Epub ahead of print] doi:10.1038/ncomms2762
Epub:
Not Epub
Abstract:
Smad2/3-mediated transforming growth factor β signalling and the Ras-Raf-Mek-Erk cascade have important roles in stem cell and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu X, Xiong C, Jia S, Zhang Y, Chen Y-G, Wang Q, Meng A. Araf kinase antagonizes Nodal-Smad2 activity in mesendoderm development by directly phosphorylating the Smad2 linker region. Nat Commun. 2013;[Epub ahead of print] doi:10.1038/ncomms2762.

Assessing Teratogenic Changes in a Zebrafish Model of Fetal Alcohol Exposure

Authors:
Loucks E, Ahlgren S
Citation:
J Vis Exp. 2012;61:e3704. DOI: 10.3791/3704
Epub:
Not Epub
Abstract:
Fetal alcohol syndrome (FAS) is a severe manifestation of embryonic exposure to ethanol. It presents with characteristic...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Loucks E, Ahlgren S. Assessing Teratogenic Changes in a Zebrafish Model of Fetal Alcohol Exposure. J Vis Exp. 2012;61:e3704. DOI: 10.3791/3704.

Auger Radiation-Induced, Antisense-Mediated Cytotoxicity of Tumor Cells Using a 3-Component Streptavidin-Delivery Nanoparticle with 111In

Authors:
Liu X, Wang Y, Nakamura K, Kawauchi S, Akalin A, Cheng D, Chen L, Rusckowski M, Hnatowich DJ
Citation:
J Nucl Med. 2009 Apr;50(4):582-90. doi: 10.2967/jnumed.108.056366. Epub 2009 Mar 16
Epub:
Not Epub
Abstract:
When antisense oligomers are intracellular, they migrate to and are retained in the nucleus of tumor cells and therefore may be...
Delivery Method:
Nanoparticle
Organism or Cell Type:
mice
Citation Extract:
Liu X, Wang Y, Nakamura K, Kawauchi S, Akalin A, Cheng D, Chen L, Rusckowski M, Hnatowich DJ. Auger Radiation-Induced, Antisense-Mediated Cytotoxicity of Tumor Cells Using a 3-Component Streptavidin-Delivery Nanoparticle with 111In. J Nucl Med. 2009 Apr;50(4):582-90. doi: 10.2967/jnumed.108.056366. Epub 2009 Mar 16.

Auger-mediated cytotoxicity of cancer cells in culture by an 125I-antisense oligomer delivered as a three-component streptavidin nanoparticle

Authors:
Liu X, Nakamura K, Wang Y, Cheng D, Liang M, Xiao N, Chen L, Rusckowski M, Hnatowich DJ
Citation:
J Biomed Nanotechnol. 2010 Apr;6(2):153-7
Epub:
Not Epub
Abstract:
We reported recently that a three-component nanoparticle, consisting of a targeting antibody, a transfecting peptide and an...
Citation Extract:
Liu X, Nakamura K, Wang Y, Cheng D, Liang M, Xiao N, Chen L, Rusckowski M, Hnatowich DJ. Auger-mediated cytotoxicity of cancer cells in culture by an 125I-antisense oligomer delivered as a three-component streptavidin nanoparticle. J Biomed Nanotechnol. 2010 Apr;6(2):153-7.

BCDO2 acts as a carotenoid scavenger and gatekeeper for the mitochondrial apoptotic pathway

Authors:
Lobo GP, Isken A, Hoff S, Babino D, von Lintig J
Citation:
Development. 2012 Aug;139(16):2966-77. doi: 10.1242/dev.079632. Epub 2012 Jul 4.
Epub:
Not Epub
Abstract:
Carotenoids and their metabolites are widespread and exert key biological functions in living organisms. In vertebrates, the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lobo GP, Isken A, Hoff S, Babino D, von Lintig J. BCDO2 acts as a carotenoid scavenger and gatekeeper for the mitochondrial apoptotic pathway. Development. 2012 Aug;139(16):2966-77. doi: 10.1242/dev.079632. Epub 2012 Jul 4..

Cadherin-1, -2, and -11 expression and cadherin-2 function in the pectoral limb bud and fin of the developing zebrafish

Authors:
Liu Q, Kerstetter AE, Azodi E, Marrs JA
Citation:
Dev Dyn. 2003 Dec;228(4):734-739
Epub:
Not Epub
Abstract:
Cadherins are cell adhesion molecules that play important roles in development of a variety of organs, including the vertebrate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu Q, Kerstetter AE, Azodi E, Marrs JA. Cadherin-1, -2, and -11 expression and cadherin-2 function in the pectoral limb bud and fin of the developing zebrafish. Dev Dyn. 2003 Dec;228(4):734-739.

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