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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Zebrafish N-cadherin, encoded by the glass onion locus, plays an essential role in retinal patterning

Authors:
Malicki J, Jo H, Pujic Z
Citation:
Dev Biol. 2003 Jul 1;259(1):95-108
Epub:
Not Epub
Abstract:
Genetic screens in zebrafish identified several loci that play essential roles in the patterning of retinal architecture. Here...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Malicki J, Jo H, Pujic Z. Zebrafish N-cadherin, encoded by the glass onion locus, plays an essential role in retinal patterning. Dev Biol. 2003 Jul 1;259(1):95-108.

Zebrafish pax8 is required for otic placode induction and plays a redundant role with Pax2 genes in the maintenance of the otic placode

Authors:
Mackereth MD, Kwak SJ, Fritz A, Riley BB
Citation:
Development. 2005 Jan;132(2):371-82.
Epub:
Not Epub
Abstract:
Vertebrate Pax2 and Pax8 proteins are closely related transcription factors hypothesized to regulate early aspects of inner ear...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mackereth MD, Kwak SJ, Fritz A, Riley BB. Zebrafish pax8 is required for otic placode induction and plays a redundant role with Pax2 genes in the maintenance of the otic placode. Development. 2005 Jan;132(2):371-82..

A crucial role for hnRNP K in axon development in Xenopus laevis

Authors:
Liu Y, Gervasi C, Szaro BG
Citation:
Development. 2008 Sep;135(18):3125-35
Epub:
Not Epub
Abstract:
We report that hnRNP K, an RNA-binding protein implicated in multiple aspects of post-transcriptional gene control, is...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Liu Y, Gervasi C, Szaro BG. A crucial role for hnRNP K in axon development in Xenopus laevis. Development. 2008 Sep;135(18):3125-35.

A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish

Authors:
Liu S, Lu W, Obara T, Kuida S, Lehoczky J, Dewar K, Drummond IA, Beier DR
Citation:
Development. 2002 Dec;129(24):5839-46
Epub:
Not Epub
Abstract:
The murine autosomal recessive juvenile cystic kidney (jck) mutation results in polycystic kidney disease. We have identified...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu S, Lu W, Obara T, Kuida S, Lehoczky J, Dewar K, Drummond IA, Beier DR. A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish. Development. 2002 Dec;129(24):5839-46.

A nanoparticle for tumor targeted delivery of oligomers

Authors:
Liu X, Wang Y, Hnatowich DJ
Citation:
Methods Mol Biol. 2011;764:91-105. doi: 10.1007/978-1-61779-188-8_6
Epub:
Not Epub
Abstract:
The tissue-specific delivery nanoparticle consists of an antisense oligomer, a cell-penetrating peptide, and an antitumor...
Link:
http://link.springer.com/protocol/10.1007%2F978-1-61779-188-8_6
Delivery Method:
Nanoparticle-peptide complex
Citation Extract:
Liu X, Wang Y, Hnatowich DJ. A nanoparticle for tumor targeted delivery of oligomers. Methods Mol Biol. 2011;764:91-105. doi: 10.1007/978-1-61779-188-8_6.

A Novel Anti-Tumor Inhibitor Identified by Virtual Screen with PLK1 Structure and Zebrafish Assay

Authors:
Lu J, Xin S, Meng H, Veldman M, Schoenfeld D, Che C, Yan R, Zhong H, Li S, Lin S
Citation:
PLoS ONE. 2013;8(4):e53317. doi:10.1371/journal.pone.0053317
Epub:
Not Epub
Abstract:
Polo-like kinase 1 (PLK1), one of the key regulators of mitosis, is a target for cancer therapy due to its abnormally high...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu J, Xin S, Meng H, Veldman M, Schoenfeld D, Che C, Yan R, Zhong H, Li S, Lin S. A Novel Anti-Tumor Inhibitor Identified by Virtual Screen with PLK1 Structure and Zebrafish Assay. PLoS ONE. 2013;8(4):e53317. doi:10.1371/journal.pone.0053317.

A novel antisense inhibitor of MMP-9 attenuates angiogenesis, human prostate cancer cell invasion and tumorigenicity

Authors:
London CA, Sekhon HS, Arora V, Stein DA, Iversen PL, Devi GR
Citation:
Cancer Gene Ther. 2003 Nov;10(11):823-32
Epub:
Not Epub
Abstract:
Androgen deprivation therapy causes a paradoxical elevation of matrix metalloproteinases (MMPs) including MMP-9 resulting in...
Delivery Method:
culture: scrape loading and syringe loading; mouse: IP injection
Organism or Cell Type:
in vitro: cell culture: HeLa and DU 145 cell ; in vivo: mice nude
Citation Extract:
London CA, Sekhon HS, Arora V, Stein DA, Iversen PL, Devi GR. A novel antisense inhibitor of MMP-9 attenuates angiogenesis, human prostate cancer cell invasion and tumorigenicity. Cancer Gene Ther. 2003 Nov;10(11):823-32.

A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development

Authors:
Lu G, Ren S, Korge P, Choi J, Dong Y, Weiss J, Koehler C, Chen JN, Wang Y
Citation:
Genes Dev. 2007 Apr 1;21(7):784-96. Epub 2007 Mar 20
Epub:
Not Epub
Abstract:
Mitochondria play a central role in the regulation of programmed cell death signaling. Here, we report the finding of a...
Organism or Cell Type:
zebrafish
Citation Extract:
Lu G, Ren S, Korge P, Choi J, Dong Y, Weiss J, Koehler C, Chen JN, Wang Y. A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development. Genes Dev. 2007 Apr 1;21(7):784-96. Epub 2007 Mar 20.

A TGF-beta control element required for SM alpha -actin expression in vivo also partially mediates GKLF-dependent transcriptional repression.

Authors:
Liu Y, Sinha S, Owens GK.
Citation:
J Biol Chem. 2003 Nov 28; 278(48): 48004-11. Epub 2003 Sep 10.
Epub:
Not Epub
Abstract:
We previously demonstrated that a conserved TGF-beta control element (TCE) within the 5 region of the smooth muscle cell (SMC)...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: rat aortic smooth muscle cells
Citation Extract:
Liu Y, Sinha S, Owens GK.. A TGF-beta control element required for SM alpha -actin expression in vivo also partially mediates GKLF-dependent transcriptional repression.. J Biol Chem. 2003 Nov 28; 278(48): 48004-11. Epub 2003 Sep 10..

A Unique Feature of Toll/IL-1 Receptor Domain-Containing Adaptor Protein Is Partially Responsible for Lipopolysaccharide Insensitivity in Zebrafish with a Highly Conserved Function of Myd88

Authors:
Liu Y, Li M, Fan S, Lin Y, Lin B, Luo F, Zhang C, Chen S, Li Y, Xu A
Citation:
J Immunol. 2010 Aug 11. [Epub ahead of print]
Epub:
Not Epub
Abstract:
MyD88 and Toll/IL-1R domain-containing adaptor protein (TIRAP) are required for the TLR4 response to LPS stimulation in mammals...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu Y, Li M, Fan S, Lin Y, Lin B, Luo F, Zhang C, Chen S, Li Y, Xu A. A Unique Feature of Toll/IL-1 Receptor Domain-Containing Adaptor Protein Is Partially Responsible for Lipopolysaccharide Insensitivity in Zebrafish with a Highly Conserved Function of Myd88. J Immunol. 2010 Aug 11. [Epub ahead of print].

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