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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Chemical genetics: adding to the developmental biology toolbox
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Citation:
Dev Cell. 2003 Jul;5(1):11-9. Review Epub:
Not Epub Abstract:
Recent advances in cell and molecular biology have generated important tools to probe developmental questions. In addition, new... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Yeh JR, Crews CM. Chemical genetics: adding to the developmental biology toolbox. Dev Cell. 2003 Jul;5(1):11-9. Review. |
Coding region polyadenylation generates a truncated tRNA synthetase that counters translation repression
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Citation:
Cell. 2012 Mar 30;149(1):88-100. doi: 10.1016/j.cell.2012.02.018. Epub 2012 Mar 1 Epub:
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Posttranscriptional regulatory mechanisms superimpose \"fine-tuning\" control upon \"on-off\" switches... Delivery Method:
Electroporation Organism or Cell Type:
cell culture: U937 and human PBM Citation Extract: Yao P, Potdar AA, Arif A, Ray PS, Mukhopadhyay R, Willard B, Xu Y, Yan J, Saidel GM, Fox PL. Coding region polyadenylation generates a truncated tRNA synthetase that counters translation repression. Cell. 2012 Mar 30;149(1):88-100. doi: 10.1016/j.cell.2012.02.018. Epub 2012 Mar 1. |
Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency
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Citation:
Mol Ther Nucleic Acids. 2013 Sep 24;2:e124. doi: 10.1038/mtna.2013.51 Epub:
Not Epub Abstract:
We have recently reported that cell-penetrating peptides (CPPs) and novel chimeric peptides containing CPP (referred as B... Delivery Method:
peptide-coupled Organism or Cell Type:
mice, mdx Citation Extract: Yin H, Boisguerin P, Moulton HM, Betts C, Seow Y, Boutilier J, Wang Q, Walsh A, Lebleu B, Wood MJ. Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency. Mol Ther Nucleic Acids. 2013 Sep 24;2:e124. doi: 10.1038/mtna.2013.51. |
CPP-Directed Oligonucleotide Exon Skipping in Animal Models of Duchenne Muscular Dystrophy
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Citation:
Methods Mol Biol. 2011;683:321-38 Epub:
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Antisense oligonucleotides (AOs) are effective splice switching agents and have potential as therapeutics via the exclusion or... Delivery Method:
peptide-coupled Citation Extract: Yin H, Moulton H, Betts C, Wood M. CPP-Directed Oligonucleotide Exon Skipping in Animal Models of Duchenne Muscular Dystrophy. Methods Mol Biol. 2011;683:321-38. |
Cross-talk between bone morphogenetic protein and transforming growth factor-beta signaling is essential for exendin-4-induced insulin-positive differentiation of AR42J cells
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Citation:
J Biol Chem. 2005 Sep 16;280(37):32209-17. Epub 2005 Jul 14 Epub:
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A key goal of cellular engineering is to manipulate progenitor cells to become beta-cells, allowing cell replacement therapy to... Delivery Method:
Scrape Delivery Organism or Cell Type:
Cell culture: rat AR42J Citation Extract: Yew KH, Hembree M, Prasadan K, Preuett B, McFall C, Benjes C, Crowley A, Sharp S, Tulachan S, Mehta S, Tei E, Gittes G. Cross-talk between bone morphogenetic protein and transforming growth factor-beta signaling is essential for exendin-4-induced insulin-positive differentiation of AR42J cells. J Biol Chem. 2005 Sep 16;280(37):32209-17. Epub 2005 Jul 14. |
Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish
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Dev Cell. 2010 Feb 16;18(2):226-36 Epub:
Not Epub Abstract:
Cell polarity is crucial for directed migration. Here we show that phosphoinositide 3-kinase (PI(3)K) mediates neutrophil... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Yoo SK, Deng Q, Cavnar PJ, Wu YI, Hahn KM, Huttenlocher A. Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish. Dev Cell. 2010 Feb 16;18(2):226-36. |
Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors
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Citation:
Mol Cell. 2012 Feb 10;45(3):330-43. doi: 10.1016/j.molcel.2011.11.032 Epub:
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Polycomb repressive complexes (PRCs) play key roles in developmental epigenetic regulation. Yet the mechanisms that target PRCs... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Yu M, Mazor T, Huang H, Huang HT, Kathrein KL, Woo AJ, Chouinard CR, Labadorf A, Akie TE, Moran TB, Xie H, Zacharek S, Taniuchi I, Roeder RG, Kim CF, Zon LI, Fraenkel E, Cantor AB. Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. Mol Cell. 2012 Feb 10;45(3):330-43. doi: 10.1016/j.molcel.2011.11.032. |
Early redox, Src family kinase, and calcium signaling integrate wound responses and tissue regeneration in zebrafish
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Citation:
J Cell Biol. 2012;[Epub ahead of print] doi:10.1083/jcb.201203154 Epub:
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Tissue injury can lead to scar formation or tissue regeneration. How regenerative animals sense initial tissue injury and... Organism or Cell Type:
zebrafish Citation Extract: Yoo SK, Freisinger CM, LeBert DC, Huttenlocher A. Early redox, Src family kinase, and calcium signaling integrate wound responses and tissue regeneration in zebrafish. J Cell Biol. 2012;[Epub ahead of print] doi:10.1083/jcb.201203154 . |
Effects of light illumination and the expression of wee1 on tissue regeneration in adult zebrafish
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Citation:
Biochem Biophys Res Commun. 2012 Oct 10. pii: S0006-291X(12)01958-4. doi: 10.1016/j.bbrc.2012.10.021. [Epub ahead of print] Epub:
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The zebrafish exhibits an enhanced capability of regenerating most of its adult tissues. In this study, we examine the roles of... Delivery Method:
Injection Organism or Cell Type:
zebrafish Citation Extract: Ye Q, Chen D, Xi Y, Li J, Shao J, Li L. Effects of light illumination and the expression of wee1 on tissue regeneration in adult zebrafish. Biochem Biophys Res Commun. 2012 Oct 10. pii: S0006-291X(12)01958-4. doi: 10.1016/j.bbrc.2012.10.021. [Epub ahead of print]. |
Efficacy of systemic morpholino exon-skipping in duchenne dystrophy dogs
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Citation:
Ann Neurol. 2009 Jun;65(6):667-76. doi: 10.1002/ana.21627. Epub:
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OBJECTIVE: Duchenne muscular dystrophy (DMD) is caused by the inability to produce dystrophin protein at the myofiber membrane... Delivery Method:
in vivo: injection Organism or Cell Type:
Dog, beagle CXMD (DMD model) Citation Extract: Yokota T, Lu QL, Partridge T, Kobayashi M, Nakamura A, Takeda S, Hoffman E. Efficacy of systemic morpholino exon-skipping in duchenne dystrophy dogs. Ann Neurol. 2009 Jun;65(6):667-76. doi: 10.1002/ana.21627.. |