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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Antisense oligo-mediated multiple exon skipping in a dog model of duchenne muscular dystrophy

Authors:
Yokota T, Hoffman E, Takeda S
Citation:
Methods Mol Biol. 2011;709:299-312
Epub:
Not Epub
Abstract:
Exon skipping is currently one of the most promising molecular therapies for Duchenne muscular -dystrophy (DMD). We have...
Delivery Method:
Injection
Organism or Cell Type:
Dog, beagle CXMD (DMD model)
Citation Extract:
Yokota T, Hoffman E, Takeda S. Antisense oligo-mediated multiple exon skipping in a dog model of duchenne muscular dystrophy. Methods Mol Biol. 2011;709:299-312.

Antisense targeting of CXXC finger protein 1 inhibits genomic cytosine methylation and primitive hematopoiesis in zebrafish

Authors:
Young SR, Mumaw C, Marrs JA, Skalnik DG
Citation:
J Biol Chem. 2006 Oct 4; [Epub ahead of print]
Epub:
Not Epub
Abstract:
CXXC Finger Protein 1 (CFP1) binds to unmethylated CpG dinucleotides, and is a component of the Set1 histone methyltransferase...
Organism or Cell Type:
zebrafish
Citation Extract:
Young SR, Mumaw C, Marrs JA, Skalnik DG. Antisense targeting of CXXC finger protein 1 inhibits genomic cytosine methylation and primitive hematopoiesis in zebrafish. J Biol Chem. 2006 Oct 4; [Epub ahead of print].

ATM gene regulates oxygen-glucose deprivation-induced nuclear factor-kappaB DNA-binding activity and downstream apoptotic cascade in mouse cerebrovascular endothelial cells

Authors:
Yin KJ, Chen SD, Lee JM, Xu J, Hsu CY
Citation:
Stroke. 2002 Oct;33(10):2471-7
Epub:
Not Epub
Abstract:
BACKGROUND AND PURPOSE: Cells lacking the ATM (ataxia telangectasia mutated) gene are hypersensitive to DNA damage caused by a...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: mouse cerebral endothelial cells
Citation Extract:
Yin KJ, Chen SD, Lee JM, Xu J, Hsu CY. ATM gene regulates oxygen-glucose deprivation-induced nuclear factor-kappaB DNA-binding activity and downstream apoptotic cascade in mouse cerebrovascular endothelial cells. Stroke. 2002 Oct;33(10):2471-7.

Atoh8, a bHLH transcription factor, is required for the development of retina and skeletal muscle in zebrafish

Authors:
Yao J, Zhou J, Liu Q, Lu D, Wang L, Qiao X, Jia W
Citation:
PLoS One. 2010 Jun 3;5(6):e10945
Epub:
Not Epub
Abstract:
BACKGROUND: Math6/atoh8, a bHLH transcription factor, is thought to be indispensable for early embryonic development and likely...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yao J, Zhou J, Liu Q, Lu D, Wang L, Qiao X, Jia W. Atoh8, a bHLH transcription factor, is required for the development of retina and skeletal muscle in zebrafish. PLoS One. 2010 Jun 3;5(6):e10945.

Axial protocadherin (AXPC) regulates cell fate during notochordal morphogenesis

Authors:
Yoder MD, Gumbiner BM
Citation:
Dev. Dyn. 2011;[Epub ahead of print] doi:10.1002/dvdy.22754
Epub:
Not Epub
Abstract:
The separation and specification of mesoderm into the notochord and somites involves members of the non-clustered δ-...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yoder MD, Gumbiner BM. Axial protocadherin (AXPC) regulates cell fate during notochordal morphogenesis. Dev. Dyn. 2011;[Epub ahead of print] doi:10.1002/dvdy.22754.

Bardet-Biedl syndrome genes are important in retrograde intracellular trafficking and Kupffer's vesicle cilia function

Authors:
Yen HJ, Tayeh MK, Mullins RF, Stone EM, Sheffield VC, Slusarski DC
Citation:
Hum Mol Genet. 2006 Mar 1;15(5):667-77. Epub 2006 Jan 6.
Epub:
Not Epub
Abstract:
Bardet-Biedl syndrome (BBS) is characterized by obesity, retinopathy, polydactyly, cognitive impairment, renal and cardiac...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yen HJ, Tayeh MK, Mullins RF, Stone EM, Sheffield VC, Slusarski DC. Bardet-Biedl syndrome genes are important in retrograde intracellular trafficking and Kupffer's vesicle cilia function. Hum Mol Genet. 2006 Mar 1;15(5):667-77. Epub 2006 Jan 6..

bloodthirsty, an RBCC/TRIM gene required for erythropoiesis in zebrafish

Authors:
Yergeau DA, Cornell CN, Parker SK, Zhou Y, Detrich HW 3rd
Citation:
Dev Biol. 2005 Jul 1;283(1):97-112.
Epub:
Not Epub
Abstract:
The Antarctic icefishes (family Channichthyidae, suborder Notothenioidei) constitute the only vertebrate taxon that fails to...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yergeau DA, Cornell CN, Parker SK, Zhou Y, Detrich HW 3rd. bloodthirsty, an RBCC/TRIM gene required for erythropoiesis in zebrafish. Dev Biol. 2005 Jul 1;283(1):97-112..

BMP and non-canonical Wnt signaling are required for inhibition of secondary tail formation in zebrafish

Authors:
Yang Y, Thorpe C
Citation:
Development. 2011 Jun;138(12):2601-11
Epub:
Not Epub
Abstract:
The role of bone morphogenetic protein (BMP) signaling in specifying cell fate in the zebrafish tailbud has been well...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang Y, Thorpe C. BMP and non-canonical Wnt signaling are required for inhibition of secondary tail formation in zebrafish. Development. 2011 Jun;138(12):2601-11.

Ccm3 functions in a manner distinct from Ccm1 and Ccm2 in a zebrafish model of CCM vascular disease

Authors:
Yoruk B, Gillersa BS, Chi NC, Scott IC
Citation:
Dev Biol. 2011;[Epub ahead of print] doi:10.1016/j.ydbio.2011.12.006
Epub:
Not Epub
Abstract:
Cerebral cavernous malformations (CCMs) are vascular anomalies of the central nervous system that arise due to mutations in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yoruk B, Gillersa BS, Chi NC, Scott IC. Ccm3 functions in a manner distinct from Ccm1 and Ccm2 in a zebrafish model of CCM vascular disease. Dev Biol. 2011;[Epub ahead of print] doi:10.1016/j.ydbio.2011.12.006.

Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function

Authors:
Yin H, Moulton HM, Seow Y, Boyd C, Boutilier J, Iverson P, Wood MJ
Citation:
Hum Mol Genet. 2008 Sep 10. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Antisense oligonucleotides (AOs) have the potential to induce functional dystrophin protein expression via exon skipping by...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice, mdx
Citation Extract:
Yin H, Moulton HM, Seow Y, Boyd C, Boutilier J, Iverson P, Wood MJ. Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function. Hum Mol Genet. 2008 Sep 10. [Epub ahead of print].

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