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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

RASA1 functions in EPHB4 signaling pathway to suppress endothelial mTORC1 activity

Authors:
Kawasaki J, Aegerter S, Fevurly RD, Mammoto A, Mammoto T, Sahin M, Mably JD, Fishman SJ, Chan J
Citation:
J Clin Invest. 2014 May 16. pii: 67084. doi: 10.1172/JCI67084. [Epub ahead of print]
Epub:
Yes
Abstract:
Vascular malformations are linked to mutations in RAS p21 protein activator 1 (RASA1, also known as p120RasGAP); however, due...
Organism or Cell Type:
zebrafish
Citation Extract:
Kawasaki J, Aegerter S, Fevurly RD, Mammoto A, Mammoto T, Sahin M, Mably JD, Fishman SJ, Chan J. RASA1 functions in EPHB4 signaling pathway to suppress endothelial mTORC1 activity. J Clin Invest. 2014 May 16. pii: 67084. doi: 10.1172/JCI67084. [Epub ahead of print].

The arginine methyltransferase NDUFAF7 is essential for complex I assembly and early vertebrate embryogenesis

Authors:
Zurita O, Silva Neiva L, Sasarman F, Shoubridge EA
Citation:
Hum Mol Genet. 2014 May 16. pii: ddu239. [Epub ahead of print]
Epub:
Yes
Abstract:
Complex I of the mitochondrial respiratory chain is a large multi-subunit enzyme that assembles from nuclear and mtDNA-encoded...
Organism or Cell Type:
zebrafish
Citation Extract:
Zurita O, Silva Neiva L, Sasarman F, Shoubridge EA. The arginine methyltransferase NDUFAF7 is essential for complex I assembly and early vertebrate embryogenesis. Hum Mol Genet. 2014 May 16. pii: ddu239. [Epub ahead of print].

NIM811, a cyclophilin inhibitor without immunosuppressive activity, is beneficial in collagen VI congenital muscular dystrophy models

Authors:
Zulian A, Rizzo E, Schiavone M, Palma E, Tagliavini F, Blaauw B, Merlini L, Maraldi NM, Sabatelli P, Braghetta P, Bonaldo P, Argenton F, Bernardi P
Citation:
Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu254
Epub:
Yes
Abstract:
Ullrich Congenital Muscular Dystrophy (UCMD) and Bethlem Myopathy (BM) are inherited muscle diseases due to mutations in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zulian A, Rizzo E, Schiavone M, Palma E, Tagliavini F, Blaauw B, Merlini L, Maraldi NM, Sabatelli P, Braghetta P, Bonaldo P, Argenton F, Bernardi P. NIM811, a cyclophilin inhibitor without immunosuppressive activity, is beneficial in collagen VI congenital muscular dystrophy models. Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu254 .

Local cell interactions and self-amplifying individual cell ingression drive amniote gastrulation

Authors:
Voiculescu O, Bodenstein L, Lau I-J, Stern CD
Citation:
eLife. 2014;3:e01817 doi:10.7554/eLife.01817
Epub:
Not Epub
Abstract:
Gastrulation generates three layers of cells (ectoderm, mesoderm, endoderm) from a single sheet, while large scale cell...
Delivery Method:
electroporation
Organism or Cell Type:
chick
Citation Extract:
Voiculescu O, Bodenstein L, Lau I-J, Stern CD. Local cell interactions and self-amplifying individual cell ingression drive amniote gastrulation. eLife. 2014;3:e01817 doi:10.7554/eLife.01817.

Thrombin receptor regulates hematopoiesis and endothelial-to-hematopoietic transition

Authors:
Yue R, Li H, Liu H, Li Y, Wei B, Gao G, Jin Y, Liu T, Wei L, Du J, Pei G
Citation:
Dev Cell. 2012 May 15;22(5):1092-100. doi: 10.1016/j.devcel.2012.01.025. Epub 2012 Apr 19
Epub:
Not Epub
Abstract:
Hematopoietic development and vascular development are closely related physiological processes during vertebrate embryogenesis...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yue R, Li H, Liu H, Li Y, Wei B, Gao G, Jin Y, Liu T, Wei L, Du J, Pei G. Thrombin receptor regulates hematopoiesis and endothelial-to-hematopoietic transition. Dev Cell. 2012 May 15;22(5):1092-100. doi: 10.1016/j.devcel.2012.01.025. Epub 2012 Apr 19.

SCUBE3 (Signal Peptide-CUB-EGF Domain-containing Protein 3) Modulates Fibroblast Growth Factor Signaling during Fast Muscle Development

Authors:
Tu C-F, Tsao K-C, Lee S-J, Yang R-B
Citation:
J Biol Chem. 2014;[Epub ahead of print] doi:10.1074/jbc.M114.551929
Epub:
Yes
Abstract:
SCUBE3 (signal peptide CUB-EGF-like domain-containing protein 3) belongs to a newly identified secreted and cell membrane-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tu C-F, Tsao K-C, Lee S-J, Yang R-B. SCUBE3 (Signal Peptide-CUB-EGF Domain-containing Protein 3) Modulates Fibroblast Growth Factor Signaling during Fast Muscle Development. J Biol Chem. 2014;[Epub ahead of print] doi:10.1074/jbc.M114.551929 .

The Hippo Pathway Controls a Switch between Retinal Progenitor Cell Proliferation and Photoreceptor Cell Differentiation in Zebrafish

Authors:
Asaoka Y, Hata S, Namae M, Furutani-Seiki M, Nishina H
Citation:
PLoS ONE. 2014;9(5):e97365. doi:10.1371/journal.pone.0097365
Epub:
Not Epub
Abstract:
The precise regulation of numbers and types of neurons through control of cell cycle exit and terminal differentiation is an...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Asaoka Y, Hata S, Namae M, Furutani-Seiki M, Nishina H. The Hippo Pathway Controls a Switch between Retinal Progenitor Cell Proliferation and Photoreceptor Cell Differentiation in Zebrafish. PLoS ONE. 2014;9(5):e97365. doi:10.1371/journal.pone.0097365.

Transmission from the dominant input shapes the stereotypic ratio of photoreceptor inputs onto horizontal cells

Authors:
Yoshimatsu T, Williams PR, D'Orazi FD, Suzuki SC, Fadool JM, Allison WT, Raymond PA, Wong RO
Citation:
Nat Commun. 2014 May 15;5:3699. doi: 10.1038/ncomms4699
Epub:
Not Epub
Abstract:
Many neurons receive synapses in stereotypic proportions from converging but functionally distinct afferents. However,...
Organism or Cell Type:
zebrafish
Citation Extract:
Yoshimatsu T, Williams PR, D'Orazi FD, Suzuki SC, Fadool JM, Allison WT, Raymond PA, Wong RO. Transmission from the dominant input shapes the stereotypic ratio of photoreceptor inputs onto horizontal cells. Nat Commun. 2014 May 15;5:3699. doi: 10.1038/ncomms4699.

Characterization of Microtubule-Binding and Dimerization Activity of Giardia lamblia End-Binding 1 Protein

Authors:
Kim J, Nagami S, Lee K-H, Park S-J
Citation:
PLoS ONE. 2014;9(5):e97850. doi:10.1371/journal.pone.0097850
Epub:
Not Epub
Abstract:
End-binding 1 (EB1) proteins are evolutionarily conserved components of microtubule (MT) plus-end tracking protein that...
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Kim J, Nagami S, Lee K-H, Park S-J. Characterization of Microtubule-Binding and Dimerization Activity of Giardia lamblia End-Binding 1 Protein. PLoS ONE. 2014;9(5):e97850. doi:10.1371/journal.pone.0097850.

Use of antagonists and morpholinos in loss-of-function analyses: estrogen receptor ESR2a mediates the effects of 17alpha-ethinylestradiol on primordial germ cell distribution in zebrafish

Authors:
Hu J, Sun S, Guo M, Song H
Citation:
Reprod Biol Endocrinol. 2014;12:40 doi:10.1186/1477-7827-12-40
Epub:
Not Epub
Abstract:
Background: Various chemicals released into the aquatic environment adversely affect the reproductive system of fish,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu J, Sun S, Guo M, Song H. Use of antagonists and morpholinos in loss-of-function analyses: estrogen receptor ESR2a mediates the effects of 17alpha-ethinylestradiol on primordial germ cell distribution in zebrafish. Reprod Biol Endocrinol. 2014;12:40 doi:10.1186/1477-7827-12-40.

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