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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling

Authors:
Herhaus L, Al-Salihi MA, Dingwell KS, Cummins TD, Wasmus L, Vogt J, Ewan R, Bruce D, Macartney T, Weidlich S, Smith JC, Sapkota GP
Citation:
Open Biol. 2014 May;4(5). pii: 140065. doi: 10.1098/rsob.140065
Epub:
Not Epub
Abstract:
Protein kinase ALK3/BMPR1A mediates bone morphogenetic protein (BMP) signalling through phosphorylation and activation of SMADs...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Herhaus L, Al-Salihi MA, Dingwell KS, Cummins TD, Wasmus L, Vogt J, Ewan R, Bruce D, Macartney T, Weidlich S, Smith JC, Sapkota GP. USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling. Open Biol. 2014 May;4(5). pii: 140065. doi: 10.1098/rsob.140065.

The dlx5a/dlx6a Genes Play Essential Roles in the Early Development of Zebrafish Median Fin and Pectoral Structures

Authors:
Heude É, Shaikho S, Ekker M
Citation:
PLoS ONE. 2014;9(5):e98505. doi:10.1371/journal.pone.0098505
Epub:
Not Epub
Abstract:
The Dlx5 and Dlx6 genes encode homeodomain transcription factors essential for the proper development of limbs in mammalian...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Heude É, Shaikho S, Ekker M. The dlx5a/dlx6a Genes Play Essential Roles in the Early Development of Zebrafish Median Fin and Pectoral Structures. PLoS ONE. 2014;9(5):e98505. doi:10.1371/journal.pone.0098505.

Endothelin signalling in iridophore development and stripe pattern formation of zebrafish

Authors:
Krauss J, Frohnhöfer HG, Walderich B, Maischein HM, Weiler C, Irion U, Nüsslein-Volhard C
Citation:
Biol Open. 2014 May 23. pii: BIO20148441. doi: 10.1242/bio.20148441. [Epub ahead of print]
Epub:
Yes
Abstract:
Colour patterns of adult fish are composed of several different types of pigment cells distributing in the skin during juvenile...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Krauss J, Frohnhöfer HG, Walderich B, Maischein HM, Weiler C, Irion U, Nüsslein-Volhard C. Endothelin signalling in iridophore development and stripe pattern formation of zebrafish. Biol Open. 2014 May 23. pii: BIO20148441. doi: 10.1242/bio.20148441. [Epub ahead of print].

Lysophosphatidic acid acts as a nutrient-derived developmental cue to regulate early hematopoiesis

Authors:
Li H, Yue R, Wei B, Gao G, Du J, Pei G
Citation:
EMBO J. 2014 2014 Jun 17;33(12):1383-96. doi: 10.15252/embj.201387594. Epub 2014 May 14
Epub:
Not Epub
Abstract:
Primitive hematopoiesis occurs in the yolk sac blood islands during vertebrate embryogenesis, where abundant...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li H, Yue R, Wei B, Gao G, Du J, Pei G. Lysophosphatidic acid acts as a nutrient-derived developmental cue to regulate early hematopoiesis. EMBO J. 2014 2014 Jun 17;33(12):1383-96. doi: 10.15252/embj.201387594. Epub 2014 May 14.

Nanoprobe-based genetic testing

Authors:
Zu Y, Tan M-H, Chowbay B, Lee SC, Yap H, Lee MT, Lu L-S, Chang C-P, Ying JY
Citation:
NanoToday. 2014;[Epub ahead of print] doi:10.1016/j.nantod.2014.04.003
Epub:
Yes
Abstract:
Plasmonic nanoprobes functionalized with morpholino oligos have been developed for genotyping of single-nucleotide...
Citation Extract:
Zu Y, Tan M-H, Chowbay B, Lee SC, Yap H, Lee MT, Lu L-S, Chang C-P, Ying JY. Nanoprobe-based genetic testing. NanoToday. 2014;[Epub ahead of print] doi:10.1016/j.nantod.2014.04.003.

Recessive mutations in PCBD1 cause a new type of early-onset diabetes

Authors:
Simaite D, Kofent J, Gong M, Rüschendorf F, Jia S, Arn P, Bentler K, Ellaway C, Kühnen P, Hoffmann GF, Blau N, Spagnoli FM, Hübner N, Raile K
Citation:
Diabetes. 2014;[Epub ahead of print] doi:10.2337/db13-1784 1939-327X
Epub:
Yes
Abstract:
Mutations in several genes cause non-autoimmune diabetes, but numerous patients still have unclear genetic defects, hampering...
Organism or Cell Type:
Xenopus
Citation Extract:
Simaite D, Kofent J, Gong M, Rüschendorf F, Jia S, Arn P, Bentler K, Ellaway C, Kühnen P, Hoffmann GF, Blau N, Spagnoli FM, Hübner N, Raile K. Recessive mutations in PCBD1 cause a new type of early-onset diabetes. Diabetes. 2014;[Epub ahead of print] doi:10.2337/db13-1784 1939-327X .

Silencing of GRA10 protein expression inhibits Toxoplasma gondii intracellular growth and development

Authors:
Witola WH, Bauman B, McHugh M, Matthews K
Citation:
Parasitol Int. 2014 May 13. pii: S1383-5769(14)00059-2. doi: 10.1016/j.parint.2014.05.001. [Epub ahead of print]
Epub:
Yes
Abstract:
Toxoplasma gondii dense granule proteins (GRAs) are secreted abundantly in both the tachyzoite and bradyzoite stages of the...
Delivery Method:
peptide-linked
Organism or Cell Type:
Toxoplasma gondii
Citation Extract:
Witola WH, Bauman B, McHugh M, Matthews K. Silencing of GRA10 protein expression inhibits Toxoplasma gondii intracellular growth and development. Parasitol Int. 2014 May 13. pii: S1383-5769(14)00059-2. doi: 10.1016/j.parint.2014.05.001. [Epub ahead of print].

Gtpbp2 Is required for BMP signaling and mesoderm patterning in Xenopus embryos

Authors:
Kirmizitas A, Gillis WQ, Zhu H, Thomsen GH
Citation:
Dev Biol. 2014;[Epub ahead of print] doi:10.1016/j.ydbio.2014.05.008
Epub:
Yes
Abstract:
Smad proteins convey canonical intracellular signals for activated receptors in the TGFβ superfamily, but the activity of Smads...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kirmizitas A, Gillis WQ, Zhu H, Thomsen GH. Gtpbp2 Is required for BMP signaling and mesoderm patterning in Xenopus embryos. Dev Biol. 2014;[Epub ahead of print] doi:10.1016/j.ydbio.2014.05.008.

spiel ohne grenzen/pou2 is required during establishment of the zebrafish midbrain-hindbrain boundary organizer

Authors:
Belting HG, Hauptmann G, Meyer D, Abdelilah-Seyfried S, Chitnis A, Eschbach C, Söll I, Thisse C, Thisse B, Artinger KB, Lunde K, Driever W
Citation:
Development. 2001 Nov;128(21):4165-76
Epub:
Not Epub
Abstract:
The vertebrate midbrain-hindbrain boundary (MHB) organizes patterning and neuronal differentiation in the midbrain and anterior...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Belting HG, Hauptmann G, Meyer D, Abdelilah-Seyfried S, Chitnis A, Eschbach C, Söll I, Thisse C, Thisse B, Artinger KB, Lunde K, Driever W. spiel ohne grenzen/pou2 is required during establishment of the zebrafish midbrain-hindbrain boundary organizer. Development. 2001 Nov;128(21):4165-76.

Homeobox transcription factor VentX regulates differentiation and maturation of human dendritic cells

Authors:
Wu X, Gao H, Bleday R, Zhu Z
Citation:
J Biol Chem. 2014 May 23;289(21):14633-43. doi: 10.1074/jbc.M113.509158. Epub 2014 Apr 4
Epub:
Not Epub
Abstract:
Dendritic cells (DCs) are specialized antigen presentation cells that play critical roles in the initiation and regulation of...
Delivery Method:
electroporation
Organism or Cell Type:
Cell culture: human primary monocytes
Citation Extract:
Wu X, Gao H, Bleday R, Zhu Z. Homeobox transcription factor VentX regulates differentiation and maturation of human dendritic cells. J Biol Chem. 2014 May 23;289(21):14633-43. doi: 10.1074/jbc.M113.509158. Epub 2014 Apr 4.

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