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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Functional analysis of splicing mutations in the IDS gene and the use of antisense oligonucleotides to exploit an alternative therapy for MPS II
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Citation:
Biochim Biophys Acta. 2015 Sep 23. pii: S0925-4439(15)00283-5. doi: 10.1016/j.bbadis.2015.09.011. [Epub ahead of print] Epub:
Yes Abstract:
Mucopolysaccharidosis II is a lysosomal storage disorder caused by mutations in the IDS gene, including exonic alterations... Organism or Cell Type:
cell culture: human primary cells Citation Extract: Matos L, Gonçalves V, Pinto E, Laranjeira F, Prata MJ, Jordan P, Desviat LR, Pérez B, Alves S. Functional analysis of splicing mutations in the IDS gene and the use of antisense oligonucleotides to exploit an alternative therapy for MPS II. Biochim Biophys Acta. 2015 Sep 23. pii: S0925-4439(15)00283-5. doi: 10.1016/j.bbadis.2015.09.011. [Epub ahead of print]. |
Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function
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Citation:
Nat Commun. 2015 Sep 25;6:8391. doi: 10.1038/ncomms9391 Epub:
Not Epub Abstract:
Membrane proteins are crucial to heart function and development. Here we combine cationic silica-bead coating with shotgun... Organism or Cell Type:
zebrafish Citation Extract: Sharma P, Abbasi C, Lazic S, Teng AC, Wang D, Dubois N, Ignatchenko V, Wong V, Liu J, Araki T, Tiburcy M, Ackerley C, Zimmermann WH, Hamilton R, Sun Y, Liu PP, Keller G, Stagljar I, Scott IC, Kislinger T, Gramolini AO. Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function. Nat Commun. 2015 Sep 25;6:8391. doi: 10.1038/ncomms9391. |
HDAC3 Is Required for Posterior Lateral Line Development in Zebrafish
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Citation:
Mol Neurobiol. 2015 Sep 22. [Epub ahead of print] Epub:
Not Epub Abstract:
Histone deacetylases (HDACs) are involved in multiple developmental processes, but their functions in the development of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: He Y, Wang Z, Sun S, Tang D, Li W, Chai R, Li H. HDAC3 Is Required for Posterior Lateral Line Development in Zebrafish. Mol Neurobiol. 2015 Sep 22. [Epub ahead of print]. |
Lnx2 ubiquitin ligase is essential for exocrine cell differentiation in the early zebrafish pancreas
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Citation:
Proc Natl Acad Sci U S A. 2015 Sep 21. pii: 201517033. [Epub ahead of print] Epub:
Yes Abstract:
The gene encoding the E3 ubiquitin ligase Ligand of Numb protein-X (Lnx)2a is expressed in the ventral-anterior pancreatic bud... Organism or Cell Type:
zebrafish Citation Extract: Won M, Ro H, Dawid IB. Lnx2 ubiquitin ligase is essential for exocrine cell differentiation in the early zebrafish pancreas. Proc Natl Acad Sci U S A. 2015 Sep 21. pii: 201517033. [Epub ahead of print]. |
The Role of ARF6 in Biliary Atresia
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Citation:
PLoS One. 2015 Sep 17;10(9):e0138381. doi: 10.1371/journal.pone.0138381. eCollection 2015 Epub:
Not Epub Abstract:
BACKGROUND & AIMS: Altered extrahepatic bile ducts, gut, and cardiovascular anomalies constitute the variable phenotype of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ningappa M, So J, Glessner J, Ashokkumar C, Ranganathan S, Min J, Higgs BW, Sun Q, Haberman K, Schmitt L, Vilarinho S, Mistry PK, Vockley G, Dhawan A, Gittes GK, Hakonarson H, Jaffe R, Subramaniam S, Shin D, Sindhi R. The Role of ARF6 in Biliary Atresia. PLoS One. 2015 Sep 17;10(9):e0138381. doi: 10.1371/journal.pone.0138381. eCollection 2015. |
Knockdown of Tmem234 in zebrafish results in proteinuria
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Citation:
Am J Physiol Renal Physiol. 2015 Sep 16:ajprenal.00525.2014. doi: 10.1152/ajprenal.00525.2014. [Epub ahead of print] Epub:
Yes Abstract:
Podocytes are highly specialized epithelial cells located at the outer aspects of the glomerular capillary tuft and critical... Organism or Cell Type:
zebrafish Citation Extract: Rodriguez PQ, Oddsson A, Ebarasi L, He B, Hultenby K, Wernerson A, Betsholtz C, Tryggvason K, Patrakka J. Knockdown of Tmem234 in zebrafish results in proteinuria. Am J Physiol Renal Physiol. 2015 Sep 16:ajprenal.00525.2014. doi: 10.1152/ajprenal.00525.2014. [Epub ahead of print]. |
Solute Carrier Family 26 Member a2 (slc26a2) Regulates Otic Development and Hair Cell Survival in Zebrafish
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Citation:
PLoS One. 2015 Sep 16;10(9):e0136832. doi: 10.1371/journal.pone.0136832. eCollection 2015 Epub:
Not Epub Abstract:
Hearing loss is one of the most prevalent human birth defects. Genetic factors contribute to the pathogenesis of deafness. It... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu F, Xia W, Hu J, Wang Y, Yang F, Sun S, Zhang J, Jiang N, Wang H, Tian W, Wang X, Ma D. Solute Carrier Family 26 Member a2 (slc26a2) Regulates Otic Development and Hair Cell Survival in Zebrafish. PLoS One. 2015 Sep 16;10(9):e0136832. doi: 10.1371/journal.pone.0136832. eCollection 2015. |
Spiroindolone That Inhibits PfATPase4 Is a Potent, Cidal Inhibitor of Toxoplasma gondii Tachyzoites In Vitro and In Vivo
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Citation:
Antimicrob Agents Chemother. 2014;58(3):1789-92. doi: 10.1128/AAC.02225-13. Epub 2013 Dec 23. PMID: 24366743 Epub:
Not Epub Abstract:
Here, we show that spiroindolone, an effective treatment for plasmodia, is also active against Toxoplasma gondii tachyzoites.... Delivery Method:
peptide-linked Organism or Cell Type:
Toxoplasma gondii Citation Extract: Zhou Y, Fomovska A, Muench S, Lai BS, Mui E, McLeod R. Spiroindolone That Inhibits PfATPase4 Is a Potent, Cidal Inhibitor of Toxoplasma gondii Tachyzoites In Vitro and In Vivo. Antimicrob Agents Chemother. 2014;58(3):1789-92. doi: 10.1128/AAC.02225-13. Epub 2013 Dec 23. PMID: 24366743 . |
Genetic Defects in TAPT1 Disrupt Ciliogenesis and Cause a Complex Lethal Osteochondrodysplasia
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Citation:
Am J Hum Genet. 2015 Sep 9. pii: S0002-9297(15)00331-6. doi: 10.1016/j.ajhg.2015.08.009. [Epub ahead of print] Epub:
Yes Abstract:
The evolutionarily conserved transmembrane anterior posterior transformation 1 protein, encoded by TAPT1, is involved in murine... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Symoens S, Barnes AM, Gistelinck C, Malfait F, Guillemyn B, Steyaert W, Syx D, D'hondt S, Biervliet M, De Backer J, Witten EP, Leikin S, Makareeva E, Gillessen-Kaesbach G, Huysseune A, Vleminckx K, Willaert A, De Paepe A, Marini JC, Coucke PJ. Genetic Defects in TAPT1 Disrupt Ciliogenesis and Cause a Complex Lethal Osteochondrodysplasia. Am J Hum Genet. 2015 Sep 9. pii: S0002-9297(15)00331-6. doi: 10.1016/j.ajhg.2015.08.009. [Epub ahead of print]. |
Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation
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Citation:
Stem Cell Reports. 2015 Sep 9. pii: S2213-6711(15)00244-1. doi: 10.1016/j.stemcr.2015.08.010. [Epub ahead of print] Epub:
Yes Abstract:
Hematopoietic stem and progenitor cells (HSPCs) are born from hemogenic endothelium in the dorsal aorta. Specification of this... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cortes M, Liu SY, Kwan W, Alexa K, Goessling W, North TE. Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation. Stem Cell Reports. 2015 Sep 9. pii: S2213-6711(15)00244-1. doi: 10.1016/j.stemcr.2015.08.010. [Epub ahead of print]. |