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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Phosphorylation of heterogeneous nuclear ribonucleoprotein K at an extracellular signal-regulated kinase phosphorylation site promotes neurofilament-medium protein expression and axon outgrowth in Xenopus

Authors:
Hutchins EJ, Belrose JL, Szaro BG
Citation:
Neurosci Lett. 2015 Sep 26;607:59-65. doi: 10.1016/j.neulet.2015.09.027. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Post-transcriptional control of cytoskeletal genes fine-tunes the supply of structural materials to growing axons in response...
Link:
http://www.sciencedirect.com/science/article/pii/S0304394015301531
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Hutchins EJ, Belrose JL, Szaro BG. Phosphorylation of heterogeneous nuclear ribonucleoprotein K at an extracellular signal-regulated kinase phosphorylation site promotes neurofilament-medium protein expression and axon outgrowth in Xenopus. Neurosci Lett. 2015 Sep 26;607:59-65. doi: 10.1016/j.neulet.2015.09.027. [Epub ahead of print].

Gene Editing Versus Morphants

Authors:
Morcos PA, Vincent AC, Moulton JD
Citation:
Zebrafish. 2015 Oct;12(5):319. doi: 10.1089/zeb.2015.1114
Epub:
Not Epub
Abstract:
No abstract available.
Link:
http://online.liebertpub.com/doi/10.1089/zeb.2015.1114
Organism or Cell Type:
zebrafish
Citation Extract:
Morcos PA, Vincent AC, Moulton JD. Gene Editing Versus Morphants. Zebrafish. 2015 Oct;12(5):319. doi: 10.1089/zeb.2015.1114.

MMP21 is mutated in human heterotaxy and is required for normal left-right asymmetry in vertebrates

Authors:
Guimier A, Gabriel GC, Bajolle F, Tsang M, Liu H, Noll A, Schwartz M, El Malti R, Smith LD, Klena NT, Jimenez G, Miller NA, Oufadem M, Moreau de Bellaing A, Yagi H, Saunders CJ, Baker CN, Di Filippo S, Peterson KA, Thiffault I, Bole-Feysot C, Cooley LD, Farrow EG, Masson C, Schoen P, Deleuze JF, Nitschké P, Lyonnet S, de Pontual L, Murray SA, Bonnet D, Kingsmore SF, Amiel J, Bouvagnet P, Lo CW, Gordon CT
Citation:
Nat Genet. 2015 Oct 5. doi: 10.1038/ng.3376. [Epub ahead of print]
Epub:
Yes
Abstract:
Heterotaxy results from a failure to establish normal left-right asymmetry early in embryonic development. By whole-exome...
Link:
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3376.html
Organism or Cell Type:
zebrafish
Citation Extract:
Guimier A, Gabriel GC, Bajolle F, Tsang M, Liu H, Noll A, Schwartz M, El Malti R, Smith LD, Klena NT, Jimenez G, Miller NA, Oufadem M, Moreau de Bellaing A, Yagi H, Saunders CJ, Baker CN, Di Filippo S, Peterson KA, Thiffault I, Bole-Feysot C, Cooley LD, Farrow EG, Masson C, Schoen P, Deleuze JF, Nitschké P, Lyonnet S, de Pontual L, Murray SA, Bonnet D, Kingsmore SF, Amiel J, Bouvagnet P, Lo CW, Gordon CT. MMP21 is mutated in human heterotaxy and is required for normal left-right asymmetry in vertebrates. Nat Genet. 2015 Oct 5. doi: 10.1038/ng.3376. [Epub ahead of print].

The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway

Authors:
Luehders K, Sasai N, Davaapil H, Kurosawa-Yoshida M, Hiura H, Brah T, Ohnuma S
Citation:
Development. 2015 Oct 1;142(19):3351-61. doi: 10.1242/dev.124438
Epub:
Not Epub
Abstract:
Small leucine-rich repeat proteoglycan (SLRP) family proteins play important roles in a number of biological events. Here, we...
Link:
http://dev.biologists.org/content/142/19/3351
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Luehders K, Sasai N, Davaapil H, Kurosawa-Yoshida M, Hiura H, Brah T, Ohnuma S. The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway. Development. 2015 Oct 1;142(19):3351-61. doi: 10.1242/dev.124438.

Peptide Nucleic Acid Promotes Systemic Dystrophin Expression and Functional Rescue in Dystrophin-deficient mdx Mice

Authors:
Gao X, Shen X, Dong X, Ran N, Han G, Cao L, Gu B, Yin H
Citation:
Mol Ther Nucleic Acids. 2015 Oct 6;4:e255. doi: 10.1038/mtna.2015.27
Epub:
Not Epub
Abstract:
Antisense oligonucleotide (AO)-mediated exon-skipping therapeutics shows great promise for Duchenne muscular dystrophy (DMD)...
Link:
http://www.nature.com/mtna/journal/v4/n10/full/mtna201527a.html
Delivery Method:
injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Gao X, Shen X, Dong X, Ran N, Han G, Cao L, Gu B, Yin H. Peptide Nucleic Acid Promotes Systemic Dystrophin Expression and Functional Rescue in Dystrophin-deficient mdx Mice. Mol Ther Nucleic Acids. 2015 Oct 6;4:e255. doi: 10.1038/mtna.2015.27.

Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish

Authors:
Pauli A, Montague TG, Lennox KA, Behlke MA, Schier AF
Citation:
PLoS One. 2015 Oct 5;10(10):e0139504. doi: 10.1371/journal.pone.0139504. eCollection 2015
Epub:
Not Epub
Abstract:
Antisense oligonucleotides (ASOs) are synthetic, single-strand RNA-DNA hybrids that induce catalytic degradation of...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139504
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pauli A, Montague TG, Lennox KA, Behlke MA, Schier AF. Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish. PLoS One. 2015 Oct 5;10(10):e0139504. doi: 10.1371/journal.pone.0139504. eCollection 2015.

Limb body wall complex, amniotic band sequence, or new syndrome caused by mutation in IQ Motif containing K (IQCK)?

Authors:
Kruszka P, Uwineza A, Mutesa L, Martinez AF, Abe Y, Zackai EH, Ganetzky R, Chung B, Stevenson RE, Adelstein RS, Ma X, Mullikin JC, Hong SK, Muenke M
Citation:
Mol Genet Genomic Med. 2015 Sep;3(5):424-32. doi: 10.1002/mgg3.153. Epub 2015 May 6
Epub:
Not Epub
Abstract:
Limb body wall complex (LBWC) and amniotic band sequence (ABS) are multiple congenital anomaly conditions with craniofacial,...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/mgg3.153/abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Kruszka P, Uwineza A, Mutesa L, Martinez AF, Abe Y, Zackai EH, Ganetzky R, Chung B, Stevenson RE, Adelstein RS, Ma X, Mullikin JC, Hong SK, Muenke M. Limb body wall complex, amniotic band sequence, or new syndrome caused by mutation in IQ Motif containing K (IQCK)?. Mol Genet Genomic Med. 2015 Sep;3(5):424-32. doi: 10.1002/mgg3.153. Epub 2015 May 6.

Developmental toxicity of the PBDE metabolite 6-OH-BDE-47 in zebrafish and the potential role of thyroid receptor β

Authors:
Macaulay LJ, Chen A, Rock KD, Dishaw LV, Dong W, Hinton DE, Stapleton HM
Citation:
Aquat Toxicol. 2015 Sep 24;168:38-47. doi: 10.1016/j.aquatox.2015.09.007. [Epub ahead of print]
Epub:
Not Epub
Abstract:
6-hydroxy-2,2',4,4'-tetrabromodiphenyl ether (6-OH-BDE-47) is both a polybrominated diphenyl ether (PBDE) flame...
Link:
http://www.sciencedirect.com/science/article/pii/S0166445X15300473
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Macaulay LJ, Chen A, Rock KD, Dishaw LV, Dong W, Hinton DE, Stapleton HM. Developmental toxicity of the PBDE metabolite 6-OH-BDE-47 in zebrafish and the potential role of thyroid receptor β. Aquat Toxicol. 2015 Sep 24;168:38-47. doi: 10.1016/j.aquatox.2015.09.007. [Epub ahead of print].

Growth-Arrest-Specific 7 Gene Regulates Neural Crest Formation and Craniofacial Development in Zebrafish

Authors:
Hung FC, Shih HY, Cheng YC, Chao C
Citation:
Stem Cells Dev. 2015 Sep 28. [Epub ahead of print]
Epub:
Yes
Abstract:
Growth-arrest-specific 7 (Gas7) is preferentially expressed in the nervous system and plays an important role during...
Link:
http://online.liebertpub.com/doi/10.1089/scd.2015.0146
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hung FC, Shih HY, Cheng YC, Chao C. Growth-Arrest-Specific 7 Gene Regulates Neural Crest Formation and Craniofacial Development in Zebrafish. Stem Cells Dev. 2015 Sep 28. [Epub ahead of print].

Biallelic Mutations in Nuclear Pore Complex Subunit NUP107 Cause Early-Childhood-Onset Steroid-Resistant Nephrotic Syndrome

Authors:
Miyake N, Tsukaguchi H, Koshimizu E, Shono A, Matsunaga S, Shiina M, Mimura Y, Imamura S, Hirose T, Okudela K, Nozu K, Akioka Y, Hattori M, Yoshikawa N, Kitamura A, Cheong HI, Kagami S, Yamashita M, Fujita A, Miyatake S, Tsurusaki Y, Nakashima M, Saitsu H, Ohashi K, Imamoto N, Ryo A, Ogata K, Iijima K, Matsumoto N
Citation:
Am J Hum Genet. 2015 Sep 22. pii: S0002-9297(15)00363-8. doi: 10.1016/j.ajhg.2015.08.013. [Epub ahead of print]
Epub:
Yes
Abstract:
The nuclear pore complex (NPC) is a huge protein complex embedded in the nuclear envelope. It has central functions in...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297%2815%2900363-8
Organism or Cell Type:
zebrafish
Citation Extract:
Miyake N, Tsukaguchi H, Koshimizu E, Shono A, Matsunaga S, Shiina M, Mimura Y, Imamura S, Hirose T, Okudela K, Nozu K, Akioka Y, Hattori M, Yoshikawa N, Kitamura A, Cheong HI, Kagami S, Yamashita M, Fujita A, Miyatake S, Tsurusaki Y, Nakashima M, Saitsu H, Ohashi K, Imamoto N, Ryo A, Ogata K, Iijima K, Matsumoto N. Biallelic Mutations in Nuclear Pore Complex Subunit NUP107 Cause Early-Childhood-Onset Steroid-Resistant Nephrotic Syndrome. Am J Hum Genet. 2015 Sep 22. pii: S0002-9297(15)00363-8. doi: 10.1016/j.ajhg.2015.08.013. [Epub ahead of print].

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