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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

RAPGEF5 Regulates Nuclear Translocation of β-Catenin

Authors:
Griffin JN, del Viso F, Duncan AR, Robson A, Hwang W, Kulkarni S, Liu KJ, Khokha MK
Citation:
Dev Cell. 2017;[Epub ahead of print] doi:10.1016/j.devcel.2017.12.001
Epub:
Yes
Abstract:
Canonical Wnt signaling coordinates many critical aspects of embryonic development, while dysregulated Wnt signaling...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Griffin JN, del Viso F, Duncan AR, Robson A, Hwang W, Kulkarni S, Liu KJ, Khokha MK. RAPGEF5 Regulates Nuclear Translocation of β-Catenin. Dev Cell. 2017;[Epub ahead of print] doi:10.1016/j.devcel.2017.12.001.

The Vertebrate Protein Dead End Maintains Primordial Germ Cell Fate by Inhibiting Somatic Differentiation

Authors:
Gross-Thebing T, Yigit S, Pfeiffer J, Reichman-Fried M, Bandemer J, Ruckert C, Rathmer C, Goudarzi M, Stehling M, Tarbashevich K, Seggewiss J, Raz E
Citation:
Dev Cell. 2017 Dec 18;43(6):704-715.e5. doi: 10.1016/j.devcel.2017.11.019
Epub:
Not Epub
Abstract:
Maintaining cell fate relies on robust mechanisms that prevent the differentiation of specified cells into other cell types....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gross-Thebing T, Yigit S, Pfeiffer J, Reichman-Fried M, Bandemer J, Ruckert C, Rathmer C, Goudarzi M, Stehling M, Tarbashevich K, Seggewiss J, Raz E. The Vertebrate Protein Dead End Maintains Primordial Germ Cell Fate by Inhibiting Somatic Differentiation. Dev Cell. 2017 Dec 18;43(6):704-715.e5. doi: 10.1016/j.devcel.2017.11.019.

Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways

Authors:
Sigg MA, Menchen T, Lee C, Johnson J, Jungnickel MK, Choksi SP, Garcia G 3rd, Busengdal H, Dougherty GW, Pennekamp P, Werner C, Rentzsch F, Florman HM, Krogan N, Wallingford JB, Omran H, Reiter JF
Citation:
Dev Cell. 2017 Dec 18;43(6):744-762.e11. doi: 10.1016/j.devcel.2017.11.014
Epub:
Not Epub
Abstract:
Cilia are organelles specialized for movement and signaling. To infer when during evolution signaling pathways became...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Sigg MA, Menchen T, Lee C, Johnson J, Jungnickel MK, Choksi SP, Garcia G 3rd, Busengdal H, Dougherty GW, Pennekamp P, Werner C, Rentzsch F, Florman HM, Krogan N, Wallingford JB, Omran H, Reiter JF. Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways. Dev Cell. 2017 Dec 18;43(6):744-762.e11. doi: 10.1016/j.devcel.2017.11.014.

Long-Range Signaling Activation and Local Inhibition Separate the Mesoderm and Endoderm Lineages

Authors:
van Boxtel AL, Economou AD, Heliot C, Hill CS
Citation:
Dev Cell. 2017 Dec 20. pii: S1534-5807(17)30982-6. doi: 10.1016/j.devcel.2017.11.021. [Epub ahead of print]
Epub:
Yes
Abstract:
Specification of the three germ layers by graded Nodal signaling has long been seen as a paradigm for patterning through a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
van Boxtel AL, Economou AD, Heliot C, Hill CS. Long-Range Signaling Activation and Local Inhibition Separate the Mesoderm and Endoderm Lineages. Dev Cell. 2017 Dec 20. pii: S1534-5807(17)30982-6. doi: 10.1016/j.devcel.2017.11.021. [Epub ahead of print].

Role of the Visual Experience-Dependent Nascent Proteome in Neuronal Plasticity

Authors:
Liu H-H, McClatchy DB, Schiapparelli L, Shen W, Yates JR III, Cline HT
Citation:
bioRxiv. 2017. doi:10.1101/240119
Epub:
Yes
Abstract:
Experience-dependent synaptic plasticity refines brain circuits during development. To identify novel protein synthesis-...
Delivery Method:
intracerebroventricular injection then electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Liu H-H, McClatchy DB, Schiapparelli L, Shen W, Yates JR III, Cline HT. Role of the Visual Experience-Dependent Nascent Proteome in Neuronal Plasticity. bioRxiv. 2017. doi:10.1101/240119.

Long-Term Pulmonary Function in Duchenne Muscular Dystrophy: Comparison of Eteplirsen-Treated Patients to Natural History

Authors:
Kinane TB, Mayer OH, Duda PW, Lowes LP, Moody SL, Mendell JR
Citation:
J Neuromusc Dis. 2017;[Epub ahead of print] doi:10.3233/JND-170272
Epub:
Not Epub
Abstract:
Background: Duchenne muscular dystrophy (DMD) is a rare, degenerative, X-linked genetic disease that results in progressive...
Delivery Method:
i.v. infusion
Organism or Cell Type:
human
Citation Extract:
Kinane TB, Mayer OH, Duda PW, Lowes LP, Moody SL, Mendell JR. Long-Term Pulmonary Function in Duchenne Muscular Dystrophy: Comparison of Eteplirsen-Treated Patients to Natural History. J Neuromusc Dis. 2017;[Epub ahead of print] doi:10.3233/JND-170272.

Rnf152 Is Essential for NeuroD Expression and Delta-Notch Signaling in the Zebrafish Embryos

Authors:
Kumar A, Huh TL, Choe J, Rhee M
Citation:
Mol Cells. 2017 Dec 22. doi: 10.14348/molcells.2017.0216. [Epub ahead of print]
Epub:
Yes
Abstract:
We report the biological functions of a zebrafish homologue of RING-finger protein 152 (rnf152) during embryogenesis. rnf152...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kumar A, Huh TL, Choe J, Rhee M. Rnf152 Is Essential for NeuroD Expression and Delta-Notch Signaling in the Zebrafish Embryos. Mol Cells. 2017 Dec 22. doi: 10.14348/molcells.2017.0216. [Epub ahead of print].

Whole-exome sequencing reveals POC5 as a novel gene associated with autosomal recessive retinitis pigmentosa

Authors:
Weisz Hubshman M, Broekman S, van Wijk E, Cremers F, Abu-Diab A, Samer K, Tzur S, Lagovsky I, Smirin-Yosef P, Sharon D, Haer-Wigman L, Banin E, Basel-Vanagaite L, de Vrieze E
Citation:
Hum Mol Genet. 2017 Dec 19. doi: 10.1093/hmg/ddx428. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Retinitis pigmentosa (RP), the most common form of inherited retinal degeneration, is associated with different groups of genes...
Organism or Cell Type:
zebrafish
Citation Extract:
Weisz Hubshman M, Broekman S, van Wijk E, Cremers F, Abu-Diab A, Samer K, Tzur S, Lagovsky I, Smirin-Yosef P, Sharon D, Haer-Wigman L, Banin E, Basel-Vanagaite L, de Vrieze E. Whole-exome sequencing reveals POC5 as a novel gene associated with autosomal recessive retinitis pigmentosa. Hum Mol Genet. 2017 Dec 19. doi: 10.1093/hmg/ddx428. [Epub ahead of print].

G protein-coupled receptor gpr34l mutation affects thrombocyte function in zebrafish

Authors:
Kim S, Alsrhani A, Zafreen L, Khandekar G, Marlow FL, Abrams EW, Mullins MC, Jagadeeswaran P
Citation:
Br J Haematol. 2017 Dec 21. doi: 10.1111/bjh.15046. [Epub ahead of print]
Epub:
Yes
Abstract:
Haemostasis is a defence mechanism that has evolved to protect organisms from losing their circulating fluid. We have...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Kim S, Alsrhani A, Zafreen L, Khandekar G, Marlow FL, Abrams EW, Mullins MC, Jagadeeswaran P. G protein-coupled receptor gpr34l mutation affects thrombocyte function in zebrafish. Br J Haematol. 2017 Dec 21. doi: 10.1111/bjh.15046. [Epub ahead of print].

RNA helicase Mov10 is essential for gastrulation and CNS development

Authors:
Skariah G, Perry KJ, Drnevich J, Henry JJ, Ceman S
Citation:
Dev Dyn. 2017 Dec 21. doi: 10.1002/dvdy.24615. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Mov10 is an RNA helicase that modulates access of Argonaute 2 to microRNA recognition elements in mRNAs. We...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Skariah G, Perry KJ, Drnevich J, Henry JJ, Ceman S. RNA helicase Mov10 is essential for gastrulation and CNS development. Dev Dyn. 2017 Dec 21. doi: 10.1002/dvdy.24615. [Epub ahead of print].

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