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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Proteomic Identification Reveals the Role of Ciliary Extracellular‐Like Vesicle in Cardiovascular Function

Authors:
Mohieldin AM, Pala R, Sherpa RT, Alanazi M, Alanazi A, Shamloo K, Ahsan A, AbouAlaiwi WA, Moresco JJ. Yates JR III, Nauli SM
Citation:
Adv Sci. 2020;[Early epub] doi:10.1002/advs.201903140
Epub:
Yes
Abstract:
Primary cilia are shown to have membrane swelling, also known as ciliary bulbs. However, the role of these structures and their...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mohieldin AM, Pala R, Sherpa RT, Alanazi M, Alanazi A, Shamloo K, Ahsan A, AbouAlaiwi WA, Moresco JJ. Yates JR III, Nauli SM. Proteomic Identification Reveals the Role of Ciliary Extracellular‐Like Vesicle in Cardiovascular Function. Adv Sci. 2020;[Early epub] doi:10.1002/advs.201903140.

TPC2-mediated Ca2+ signaling is required for axon extension in caudal primary motor neurons in zebrafish embryos

Authors:
Guo C, Webb SE, Chan CM, Miller AL
Citation:
J Cell Sci. 2020;[Epub ahead of print] doi:10.1242/jcs.244780
Epub:
Not Epub
Abstract:
The role of TPC2-mediated Ca2+ release was recently characterized in zebrafish during the establishment of the early spinal...
Organism or Cell Type:
zebrafish
Citation Extract:
Guo C, Webb SE, Chan CM, Miller AL. TPC2-mediated Ca2+ signaling is required for axon extension in caudal primary motor neurons in zebrafish embryos. J Cell Sci. 2020;[Epub ahead of print] doi:10.1242/jcs.244780.

Whole-Mount In Situ Hybridization in Zebrafish Embryos and Tube Formation Assay in iPSC-ECs to Study the Role of Endoglin in Vascular Development

Authors:
Wang Y, Zhang D, Zhou F, Zhou M, Li Q, Chen J, Yang J
Citation:
J Vis Exp. 2020 May 28;(159). doi: 10.3791/60498
Epub:
Not Epub
Abstract:
Vascular development is determined by the sequential expression of specific genes, which can be studied by performing in situ...
Organism or Cell Type:
zebrafish
Citation Extract:
Wang Y, Zhang D, Zhou F, Zhou M, Li Q, Chen J, Yang J. Whole-Mount In Situ Hybridization in Zebrafish Embryos and Tube Formation Assay in iPSC-ECs to Study the Role of Endoglin in Vascular Development. J Vis Exp. 2020 May 28;(159). doi: 10.3791/60498.

Connexin43 gap junctional intercellular communication inhibits evx1 expression and joint formation in regenerating fins

Authors:
Bhattacharya S, Hyland C, Falk MM, Iovine MK
Citation:
Development. 2020;[Epub ahead of print] doi:10.1242/dev.190512
Epub:
Yes
Abstract:
The gap junction protein Connexin43 (Cx43) contributes to cell fate decisions that determine the location of fin ray joints...
Organism or Cell Type:
zebrafish
Citation Extract:
Bhattacharya S, Hyland C, Falk MM, Iovine MK. Connexin43 gap junctional intercellular communication inhibits evx1 expression and joint formation in regenerating fins. Development. 2020;[Epub ahead of print] doi:10.1242/dev.190512.

Comparative exome sequencing reveals novel candidate genes for retinitis pigmentosa

Authors:
Yi Z, Ouyang J, Sun W, Li S, Xiao X, Zhang Q
Citation:
EBioMedicine. 2020;56:102792. doi:10.1016/j.ebiom.2020.102792
Epub:
Not Epub
Abstract:
Background: Retinitis pigmentosa (RP) is the most common form of inherited retinal degeneration, but genetic defects in nearly...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yi Z, Ouyang J, Sun W, Li S, Xiao X, Zhang Q. Comparative exome sequencing reveals novel candidate genes for retinitis pigmentosa. EBioMedicine. 2020;56:102792. doi:10.1016/j.ebiom.2020.102792.

Requirement of Irf6 and Esrp1/2 in frontonasal and palatal epithelium to regulate craniofacial and palate morphogenesis in mouse and zebrafish

Authors:
Carroll SH, Trevino CM, Li EB-H, Kawasaki K, Alhazmi N, Hallett S, Cotney J, Carstens RP, Liao EC
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.06.14.149773
Epub:
Not Epub
Abstract:
Orofacial clefts are among the most common congenital structural anomalies. From genome-wide association studies over a decade...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Carroll SH, Trevino CM, Li EB-H, Kawasaki K, Alhazmi N, Hallett S, Cotney J, Carstens RP, Liao EC. Requirement of Irf6 and Esrp1/2 in frontonasal and palatal epithelium to regulate craniofacial and palate morphogenesis in mouse and zebrafish. bioRxiv. 2020;[preprint] doi:10.1101/2020.06.14.149773 .

A polo-like kinase modulates cytokinesis and flagella biogenesis in Giardia lamblia

Authors:
Park E-A, Kim J, Shin MY, Park S-J
Citation:
Research Square. 2020;[preprint]. doi:10.21203/rs.3.rs-34665/v1
Epub:
Not Epub
Abstract:
Background: Polo-like kinases (PLKs) are conserved serine/threonine kinase, regulating cell cycle. Giardia lamblia PLK (GlPLK)...
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Park E-A, Kim J, Shin MY, Park S-J. A polo-like kinase modulates cytokinesis and flagella biogenesis in Giardia lamblia. Research Square. 2020;[preprint]. doi:10.21203/rs.3.rs-34665/v1.

Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos

Authors:
Otten ABC, Kamps R, Lindsey P, Gerards M, Pendeville-Samain H, Muller M, van Tienen FHJ, Smeets HJM
Citation:
Front Cell Dev Biol. 2020;8:831. doi:10.3389/fcell.2020.00381
Epub:
Not Epub
Abstract:
High mitochondrial DNA (mtDNA) copy numbers are essential for oogenesis and embryogenesis and correlate with fertility of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Otten ABC, Kamps R, Lindsey P, Gerards M, Pendeville-Samain H, Muller M, van Tienen FHJ, Smeets HJM. Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos. Front Cell Dev Biol. 2020;8:831. doi:10.3389/fcell.2020.00381.

Use Of Non-Ablative Dose Of Radiation To Enhance Delivery Of Unmodified Morpholino Oligonucleotides In A Brain Tumor Model To Silence MGMT And Enhance The Efficacy Of Chemo-Radiation (4281)

Authors:
Ambady P, Wu J, Walker J, Kersch C, Morris DA, Bills J, Holland S, Pagel M, Muldoon L, Neuwelt E
Citation:
Neurology. 2020;94 (15 Supplement)
Epub:
Not Epub
Abstract:
Objective: Non-ablative Ionizing radiation ( XRT) is well known to alter neuro-vascular unit (NVU) permeability. We evaluate...
Delivery Method:
injection and ionizing radiation
Organism or Cell Type:
Intracranial tumor bearing athymic nude rats
Citation Extract:
Ambady P, Wu J, Walker J, Kersch C, Morris DA, Bills J, Holland S, Pagel M, Muldoon L, Neuwelt E. Use Of Non-Ablative Dose Of Radiation To Enhance Delivery Of Unmodified Morpholino Oligonucleotides In A Brain Tumor Model To Silence MGMT And Enhance The Efficacy Of Chemo-Radiation (4281). Neurology. 2020;94 (15 Supplement).

Energy and nitrogenous waste from glutamate/glutamine catabolism facilitates acute osmotic adjustment in non-neuroectodermal branchial cells

Authors:
Huang P, Liu T, Hu MY, Casties I, Tseng Y-C
Citation:
Sci Rep. 2020;10:9460. doi:10.1038/s41598-020-65913-1
Epub:
Not Epub
Abstract:
Maintenance of homeostasis is one of the most important physiological responses for animals upon osmotic perturbations....
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Huang P, Liu T, Hu MY, Casties I, Tseng Y-C. Energy and nitrogenous waste from glutamate/glutamine catabolism facilitates acute osmotic adjustment in non-neuroectodermal branchial cells. Sci Rep. 2020;10:9460. doi:10.1038/s41598-020-65913-1.

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