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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

The F-box protein Ppa is a common regulator of core EMT factors Twist, Snail, Slug, and Sip1

Authors:
Lander R, Nordin K, Carole LaBonne C
Citation:
J Cell Biol. 2011;[Epub July 4] doi:10.1083/jcb.201012085
Epub:
Not Epub
Abstract:
A small group of core transcription factors, including Twist, Snail, Slug, and Sip1, control epithelial–mesenchymal transitions...
Citation Extract:
Lander R, Nordin K, Carole LaBonne C. The F-box protein Ppa is a common regulator of core EMT factors Twist, Snail, Slug, and Sip1. J Cell Biol. 2011;[Epub July 4] doi:10.1083/jcb.201012085 .

The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity

Authors:
Laue K, Daujat S, Crump JG, Plaster N, Roehl HH; Tübingen 2000 Screen Consortium, Kimmel CB, Schneider R, Hammerschmidt M
Citation:
Development. 2008 Jun;135(11):1935-46
Epub:
Not Epub
Abstract:
The Trithorax group (TrxG) is composed of diverse, evolutionary conserved proteins that form chromatin-associated complexes...
Organism or Cell Type:
zebrafish
Citation Extract:
Laue K, Daujat S, Crump JG, Plaster N, Roehl HH; Tübingen 2000 Screen Consortium, Kimmel CB, Schneider R, Hammerschmidt M. The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity. Development. 2008 Jun;135(11):1935-46.

The PAF1 complex differentially regulates cardiomyocyte specification

Authors:
Langenbacher AD, Nguyen CT, Cavanaugh AM, Huang J, Lu F, Chen JN
Citation:
Dev Biol. 2011 May 1;353(1):19-28. Epub 2011 Feb 19
Epub:
Not Epub
Abstract:
The specification of an appropriate number of cardiomyocytes from the lateral plate mesoderm requires a careful balance of both...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Langenbacher AD, Nguyen CT, Cavanaugh AM, Huang J, Lu F, Chen JN. The PAF1 complex differentially regulates cardiomyocyte specification. Dev Biol. 2011 May 1;353(1):19-28. Epub 2011 Feb 19.

The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway

Authors:
Lawn RM, Wade DP, Garvin MR, Wang X, Schwartz K, Porter JG, Seilhamer JJ, Vaughan AM, Oram JF
Citation:
J Clin Invest 1999; 104: R25-R31
Epub:
Not Epub
Abstract:
The ABC1 transporter was identified as the defect in Tangier disease by a combined strategy of gene expression microarray...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: human fibroblasts
Citation Extract:
Lawn RM, Wade DP, Garvin MR, Wang X, Schwartz K, Porter JG, Seilhamer JJ, Vaughan AM, Oram JF. The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway. J Clin Invest 1999; 104: R25-R31.

The zebrafish Iroquois gene iro7 positions the r4/r5 boundary and controls neurogenesis in the rostral hindbrain

Authors:
Lecaudey V, Anselme I, Rosa F, Schneider-Maunoury S
Citation:
Development. 2004 Jul;131(13):3121-31.
Epub:
Not Epub
Abstract:
Early brain regionalisation involves the activation of genes coding for transcription factors in distinct domains of the neural...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lecaudey V, Anselme I, Rosa F, Schneider-Maunoury S. The zebrafish Iroquois gene iro7 positions the r4/r5 boundary and controls neurogenesis in the rostral hindbrain. Development. 2004 Jul;131(13):3121-31..

VEGF receptor 2 endocytic trafficking regulates arterial morphogenesis

Authors:
Lanahan AA, Hermans K, Claes F, Kerley-Hamilton JS, Zhuang ZW, Giordano FJ, Carmeliet P, Simons M
Citation:
Dev Cell. 2010 May 18;18(5):713-24. Epub 2010 May 6
Epub:
Not Epub
Abstract:
VEGF is the key growth factor regulating arterial morphogenesis. However, molecular events involved in this process have not...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lanahan AA, Hermans K, Claes F, Kerley-Hamilton JS, Zhuang ZW, Giordano FJ, Carmeliet P, Simons M. VEGF receptor 2 endocytic trafficking regulates arterial morphogenesis. Dev Cell. 2010 May 18;18(5):713-24. Epub 2010 May 6.

VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain

Authors:
Le Bras B, Barallobre MJ, Homman-Ludiye J, Ny A, Wyns S, Tammela T, Haiko P, Karkkainen MJ, Yuan L, Muriel MP, Chatzopoulou E, Breant C, Zalc B, Carmeliet P, Alitalo K, Eichmann A, Thomas JL
Citation:
Nat Neurosci. 2006 Mar;9(3):340-348. Epub 2006 Feb 5
Epub:
Not Epub
Abstract:
Vascular endothelial growth factor C (VEGF-C) was first identified as a regulator of the vascular system, where it is required...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Le Bras B, Barallobre MJ, Homman-Ludiye J, Ny A, Wyns S, Tammela T, Haiko P, Karkkainen MJ, Yuan L, Muriel MP, Chatzopoulou E, Breant C, Zalc B, Carmeliet P, Alitalo K, Eichmann A, Thomas JL. VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain. Nat Neurosci. 2006 Mar;9(3):340-348. Epub 2006 Feb 5.

Xenopus Cyr61 regulates gastrulation movements and modulates Wnt signalling

Authors:
Latinkic BV, Mercurio S, Bennett B, Hirst EM, Xu Q, Lau LF, Mohun TJ, Smith JC
Citation:
Development. 2003 Jun;130(11):2429-41
Epub:
Not Epub
Abstract:
Cyr61 is a secreted, heparin-binding, extracellular matrix-associated protein whose activities include the promotion of...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Latinkic BV, Mercurio S, Bennett B, Hirst EM, Xu Q, Lau LF, Mohun TJ, Smith JC. Xenopus Cyr61 regulates gastrulation movements and modulates Wnt signalling. Development. 2003 Jun;130(11):2429-41.

Zebrafish as a Model Organism for the Identification and Characterization of Drugs and Genes Affecting p53 Signaling

Authors:
Langheinrich U, Hennen E, Stott G, Vacun G
Citation:
Curr Biol. 2002 Dec 10;12(23):2023-8
Epub:
Not Epub
Abstract:
p53 and its main negative regulator, Mdm2, are key players in mammalian cancer development. Activation of the transcription...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Langheinrich U, Hennen E, Stott G, Vacun G. Zebrafish as a Model Organism for the Identification and Characterization of Drugs and Genes Affecting p53 Signaling. Curr Biol. 2002 Dec 10;12(23):2023-8.

Zebrafish embryos express an orthologue of HERG and are sensitive toward a range of QT-prolonging drugs inducing severe arrhythmia.

Authors:
Langheinrich U, Vacun G, Wagner T
Citation:
Toxicol Appl Pharmacol. 2003 Dec 15;193(3):370-82
Epub:
Not Epub
Abstract:
A wide range of drugs has been shown to prolong the QT interval of the electrocardiogram by blocking the pore-forming subunit...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Langheinrich U, Vacun G, Wagner T. Zebrafish embryos express an orthologue of HERG and are sensitive toward a range of QT-prolonging drugs inducing severe arrhythmia.. Toxicol Appl Pharmacol. 2003 Dec 15;193(3):370-82.

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