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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Microinjection of mRNA or morpholinos for reverse genetic analysis in the starlet sea anemone, Nematostella vectensis

Authors:
Layden MJ, Röttinger E, Wolenski FS, Gilmore TD, Martindale MQ
Citation:
Nat Protoc. 2013 Apr 11;8(5):924-34. doi: 10.1038/nprot.2013.009. Epub 2013 Apr 11
Epub:
Not Epub
Abstract:
We describe a protocol for microinjection of embryos for an emerging model system, the cnidarian sea anemone, Nematostella...
Delivery Method:
Microinjection
Organism or Cell Type:
Nematostella vectensis (cnidarian)
Citation Extract:
Layden MJ, Röttinger E, Wolenski FS, Gilmore TD, Martindale MQ. Microinjection of mRNA or morpholinos for reverse genetic analysis in the starlet sea anemone, Nematostella vectensis. Nat Protoc. 2013 Apr 11;8(5):924-34. doi: 10.1038/nprot.2013.009. Epub 2013 Apr 11.

MicroRNA-125b is a novel negative regulator of p53

Authors:
Le MT, Teh C, Shyh-Chang N, Xie H, Zhou B, Korzh V, Lodish HF, Lim B
Citation:
Genes Dev. 2009 Apr 1;23(7):862-76. Epub 2009 Mar 17
Epub:
Not Epub
Abstract:
The p53 transcription factor is a key tumor suppressor and a central regulator of the stress response. To ensure a robust and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Le MT, Teh C, Shyh-Chang N, Xie H, Zhou B, Korzh V, Lodish HF, Lim B. MicroRNA-125b is a novel negative regulator of p53. Genes Dev. 2009 Apr 1;23(7):862-76. Epub 2009 Mar 17.

Mutation in sodium-calcium exchanger 1 (NCX1) causes cardiac fibrillation in zebrafish

Authors:
Langenbacher AD, Dong Y, Shu X, Choi J, Nicoll DA, Goldhaber JI, Philipson KD, Chen JN
Citation:
Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17699-704. Epub 2005 Nov 28
Epub:
Not Epub
Abstract:
Cardiac fibrillation, a form of cardiac arrhythmia, is the most common cause of embolic stroke and death associated with heart...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Langenbacher AD, Dong Y, Shu X, Choi J, Nicoll DA, Goldhaber JI, Philipson KD, Chen JN. Mutation in sodium-calcium exchanger 1 (NCX1) causes cardiac fibrillation in zebrafish. Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17699-704. Epub 2005 Nov 28.

Nematostella vectensis achaete-scute homolog NvashA regulates embryonic ectodermal neurogenesis and represents an ancient component of the metazoan neural specification pathway

Authors:
Layden MJ, Boekhout M, Martindale MQ
Citation:
Development. 2012;139:1013-1022. doi:10.1242/dev.073221
Epub:
Not Epub
Abstract:
achaete-scute homologs (ash) regulate neural development in all bilaterian model animals indicating that they represent a...
Delivery Method:
Microinjection
Organism or Cell Type:
Nematostella vectensis (cnidarian)
Citation Extract:
Layden MJ, Boekhout M, Martindale MQ. Nematostella vectensis achaete-scute homolog NvashA regulates embryonic ectodermal neurogenesis and represents an ancient component of the metazoan neural specification pathway. Development. 2012;139:1013-1022. doi:10.1242/dev.073221.

Origins and unconventional behavior of neutrophils in developing zebrafish

Authors:
Le Guyader D, Redd MJ, Colucci-Guyon E, Murayama E, Kissa K, Briolat V, Mordelet E, Zapata A, Shinomiya H, Herbomel P
Citation:
Blood. 2008 Jan 1;111(1):132-41. Epub 2007 Sep 17
Epub:
Not Epub
Abstract:
The first leukocytes that arise in the development of vertebrate embryos are the primitive macrophages, which differentiate in...
Organism or Cell Type:
zebrafish
Citation Extract:
Le Guyader D, Redd MJ, Colucci-Guyon E, Murayama E, Kissa K, Briolat V, Mordelet E, Zapata A, Shinomiya H, Herbomel P. Origins and unconventional behavior of neutrophils in developing zebrafish. Blood. 2008 Jan 1;111(1):132-41. Epub 2007 Sep 17.

Otx but Not Mitf Transcription Factors Are Required for Zebrafish Retinal Pigment Epithelium Development

Authors:
Lane BM, Lister JA
Citation:
PLoS ONE. 2012;7(11):e49357. doi:10.1371/journal.pone.0049357
Epub:
Not Epub
Abstract:
Otx and Mitf transcription factors have been implicated in the development of the retinal pigmented epithelium (RPE), but the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lane BM, Lister JA. Otx but Not Mitf Transcription Factors Are Required for Zebrafish Retinal Pigment Epithelium Development. PLoS ONE. 2012;7(11):e49357. doi:10.1371/journal.pone.0049357.

Patterning of the Dorsal-Ventral Axis in Echinoderms: Insights into the Evolution of the BMP-Chordin Signaling Network

Authors:
Lapraz F, Besnardeau L, Lepage T
Citation:
PLoS Biol. 2009 Nov;7(11):e1000248. Epub 2009 Nov 24
Epub:
Not Epub
Abstract:
Formation of the dorsal-ventral axis of the sea urchin embryo relies on cell interactions initiated by the TGFbeta Nodal....
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Paracentrotus lividus
Citation Extract:
Lapraz F, Besnardeau L, Lepage T. Patterning of the Dorsal-Ventral Axis in Echinoderms: Insights into the Evolution of the BMP-Chordin Signaling Network. PLoS Biol. 2009 Nov;7(11):e1000248. Epub 2009 Nov 24.

phospholipase C gamma-1 is required downstream of vascular endothelial growth factor during arterial development

Authors:
Lawson ND, Mugford JW, Diamond BA, Weinstein BM
Citation:
Genes Dev. 2003 Jun 1;17(11):1346-51
Epub:
Not Epub
Abstract:
In this study, we utilize transgenic zebrafish with fluorescently labeled blood vessels to identify and characterize a mutant (...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lawson ND, Mugford JW, Diamond BA, Weinstein BM. phospholipase C gamma-1 is required downstream of vascular endothelial growth factor during arterial development. Genes Dev. 2003 Jun 1;17(11):1346-51.

Polycefin, a New Prototype of a Multifunctional Nanoconjugate Based on Poly(beta-l-malic acid) for Drug Delivery

Authors:
Lee BS, Fujita M, Khazenzon NM, Wawrowsky KA, Wachsmann-Hogiu S, Farkas DL, Black KL, Ljubimova JY, Holler E
Citation:
Bioconjug Chem. 2006 Mar 15;17(2):317-326
Epub:
Not Epub
Abstract:
A new prototype of nanoconjugate, Polycefin, was synthesized for targeted delivery of antisense oligonucleotides and monoclonal...
Delivery Method:
Polycefin: poly(malic acid) from Physarum polycephalum
Organism or Cell Type:
Cell culture: human glioma U87MG & T98G and in vivo
Citation Extract:
Lee BS, Fujita M, Khazenzon NM, Wawrowsky KA, Wachsmann-Hogiu S, Farkas DL, Black KL, Ljubimova JY, Holler E. Polycefin, a New Prototype of a Multifunctional Nanoconjugate Based on Poly(beta-l-malic acid) for Drug Delivery. Bioconjug Chem. 2006 Mar 15;17(2):317-326.

PTB Regulates the Processing of a 3'-Terminal Exon by Repressing both Splicing and Polyadenylation

Authors:
Le Sommer C, Lesimple M, Mereau A, Menoret S, Allo MR, Hardy S
Citation:
Mol Cell Biol. 2005 Nov;25(21):9595-607
Epub:
Not Epub
Abstract:
The polypyrimidine tract binding protein (PTB) has been described as a global repressor of regulated exons. To investigate PTB...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Le Sommer C, Lesimple M, Mereau A, Menoret S, Allo MR, Hardy S. PTB Regulates the Processing of a 3'-Terminal Exon by Repressing both Splicing and Polyadenylation. Mol Cell Biol. 2005 Nov;25(21):9595-607.

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