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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Hsp47 mediates Cx43-dependent skeletal growth and patterning in the regenerating fin

Authors:
Bhadra J, Iovine MK
Citation:
Mech Dev. 2015 Jun 20. pii: S0925-4773(15)00048-9. doi: 10.1016/j.mod.2015.06.004. [Epub ahead of print]
Epub:
Yes
Abstract:
Skeletal morphogenesis describes how bones achieve their correct shape and size and appropriately position joints. We use the...
Link:
http://www.sciencedirect.com/science/article/pii/S0925477315000489
Organism or Cell Type:
zebrafish
Citation Extract:
Bhadra J, Iovine MK. Hsp47 mediates Cx43-dependent skeletal growth and patterning in the regenerating fin. Mech Dev. 2015 Jun 20. pii: S0925-4773(15)00048-9. doi: 10.1016/j.mod.2015.06.004. [Epub ahead of print].

Response to Nodal morphogen gradient is determined by the kinetics of target gene induction

Authors:
Dubrulle J, Jordan BM, Akhmetova L, Farrell JA, Kim SH, Solnica-Krezel L, Schier AF
Citation:
Elife. 2015 Apr 14;4. doi: 10.7554/eLife.05042
Epub:
Not Epub
Abstract:
Morphogen gradients expose cells to different signal concentrations and induce target genes with different ranges of expression...
Link:
http://elifesciences.org/content/4/e05042
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dubrulle J, Jordan BM, Akhmetova L, Farrell JA, Kim SH, Solnica-Krezel L, Schier AF. Response to Nodal morphogen gradient is determined by the kinetics of target gene induction. Elife. 2015 Apr 14;4. doi: 10.7554/eLife.05042.

MiR-204 is responsible for inherited retinal dystrophy associated with ocular coloboma

Authors:
Conte I, Hadfield KD, Barbato S, Carrella S, Pizzo M, Bhat RS, Carissimo A, Karali M, Porter LF, Urquhart J, Hateley S, O'Sullivan J, Manson FD, Neuhauss SC, Banfi S, Black GC
Citation:
Proc Natl Acad Sci U S A. 2015 Jun 8. pii: 201401464. [Epub ahead of print]
Epub:
Yes
Abstract:
Ocular developmental disorders, including the group classified as microphthalmia, anophthalmia, and coloboma (MAC) and...
Link:
http://www.pnas.org/content/112/25/E3236.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Conte I, Hadfield KD, Barbato S, Carrella S, Pizzo M, Bhat RS, Carissimo A, Karali M, Porter LF, Urquhart J, Hateley S, O'Sullivan J, Manson FD, Neuhauss SC, Banfi S, Black GC. MiR-204 is responsible for inherited retinal dystrophy associated with ocular coloboma. Proc Natl Acad Sci U S A. 2015 Jun 8. pii: 201401464. [Epub ahead of print].

Shared regulatory programs suggest retention of blastula-stage potential in neural crest cells

Authors:
Buitrago-Delgado E, Nordin K, Rao A, Geary L, LaBonne C
Citation:
Science. 2015 Jun 19;348(6241):1332-5. doi: 10.1126/science.aaa3655. Epub 2015 Apr 30
Epub:
Not Epub
Abstract:
Neural crest cells, which are specific to vertebrates, arise in the ectoderm but can generate cell types that are typically...
Link:
http://www.sciencemag.org/content/348/6241/1332.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Buitrago-Delgado E, Nordin K, Rao A, Geary L, LaBonne C. Shared regulatory programs suggest retention of blastula-stage potential in neural crest cells. Science. 2015 Jun 19;348(6241):1332-5. doi: 10.1126/science.aaa3655. Epub 2015 Apr 30.

Zic1 controls placode progenitor formation non-cell autonomously by regulating retinoic acid production and transport

Authors:
Jaurena MB, Juraver-Geslin H, Devotta A, Saint-Jeannet J-P
Citation:
Nat Comm. 2015;6:7476. doi:10.1038/ncomms8476
Epub:
Not Epub
Abstract:
All cranial placode progenitors arise from a common precursor field anterior to the neural plate, the pre-placodal region (PPR...
Link:
http://www.nature.com/ncomms/2015/150623/ncomms8476/full/ncomms8476.html
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Jaurena MB, Juraver-Geslin H, Devotta A, Saint-Jeannet J-P. Zic1 controls placode progenitor formation non-cell autonomously by regulating retinoic acid production and transport. Nat Comm. 2015;6:7476. doi:10.1038/ncomms8476.

Dendritic Nanoconjugates for Intracellular Delivery of Neutral Oligonucleotides

Authors:
Ming X, Wu L, Carver K, Yuan A, Min Y
Citation:
Nanoscale. 2015;[Epub ahead of print] doi:10.1039/C5NR01665G
Epub:
Yes
Abstract:
Dendrimer-based gene delivery has been constrained by intrinsic toxicity and suboptimal nanostructure. Conjugation of neutral...
Link:
http://pubs.rsc.org/en/content/articlelanding/2015/nr/c5nr01665g#!divAbstract
Delivery Method:
PAMAM-linked
Organism or Cell Type:
cell culture: cancer cells
Citation Extract:
Ming X, Wu L, Carver K, Yuan A, Min Y. Dendritic Nanoconjugates for Intracellular Delivery of Neutral Oligonucleotides. Nanoscale. 2015;[Epub ahead of print] doi:10.1039/C5NR01665G.

Zdhhc15b Regulates Differentiation of Diencephalic Dopaminergic Neurons in Zebrafish

Authors:
Wang F, Chen X, Shi W, Yao L, Gao M, Yang Y, Hao A
Citation:
J Cell Biochem. 2015 Jun 11. doi: 10.1002/jcb.25256. [Epub ahead of print]
Epub:
Yes
Abstract:
The aspartate-histidine-histidine-cysteine (DHHC) protein family shares a 50-amino acid cysteine-rich domain with a conserved...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/jcb.25256/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang F, Chen X, Shi W, Yao L, Gao M, Yang Y, Hao A. Zdhhc15b Regulates Differentiation of Diencephalic Dopaminergic Neurons in Zebrafish. J Cell Biochem. 2015 Jun 11. doi: 10.1002/jcb.25256. [Epub ahead of print].

Ca2+ enrichment in culture medium potentiates effect of oligonucleotides

Authors:
Hori S-i, Yamamoto T, Waki R, Wada S, Wada F, Noda M, Obika S
Citation:
Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv626
Epub:
Yes
Abstract:
Antisense and RNAi-related oligonucleotides have gained attention as laboratory tools and therapeutic agents based on their...
Link:
http://nar.oxfordjournals.org/content/early/2015/06/22/nar.gkv626.full
Delivery Method:
CaCl2, Endo-Porter
Organism or Cell Type:
cell culture: Huh-7 cells
Citation Extract:
Hori S-i, Yamamoto T, Waki R, Wada S, Wada F, Noda M, Obika S. Ca2+ enrichment in culture medium potentiates effect of oligonucleotides. Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv626.

The use of urinary and kidney SILAM proteomics to monitor kidney response to high dose morpholino oligonucleotides in the mdx mouse

Authors:
Zhang A, Uaesoontrachoon K, Shaughnessy C, Das JR, Rayavarapu S, Brown KJ, Ray PE, Nagaraju K, van den Anker JN, Hoffman EP, Hathout Y
Citation:
Tox Rep. 2015;2:838-49. doi:10.1016/j.toxrep.2015.05.008
Epub:
Not Epub
Abstract:
Phosphorodiamidate morpholino oligonucleotides (PMO) are used as a promising exon-skipping gene therapy for Duchenne muscular...
Link:
http://www.sciencedirect.com/science/article/pii/S2214750015300019
Delivery Method:
injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Zhang A, Uaesoontrachoon K, Shaughnessy C, Das JR, Rayavarapu S, Brown KJ, Ray PE, Nagaraju K, van den Anker JN, Hoffman EP, Hathout Y. The use of urinary and kidney SILAM proteomics to monitor kidney response to high dose morpholino oligonucleotides in the mdx mouse. Tox Rep. 2015;2:838-49. doi:10.1016/j.toxrep.2015.05.008.

miR-181a/b control the assembly of visual circuitry by regulating retinal axon specification and growth

Authors:
Carrella S, D'Agostino Y, Barbato S, Huber-Reggi SP, Salierno FG, Manfredi A, Neuhauss SC, Banfi S, Conte I
Citation:
Dev Neurobiol. 2015 Feb 27. doi: 10.1002/dneu.22282. [Epub ahead of print]
Epub:
Yes
Abstract:
Connectivity and function of neuronal circuitry require the correct specification and growth of axons and dendrites. Here we...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dneu.22282/full
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Carrella S, D'Agostino Y, Barbato S, Huber-Reggi SP, Salierno FG, Manfredi A, Neuhauss SC, Banfi S, Conte I. miR-181a/b control the assembly of visual circuitry by regulating retinal axon specification and growth. Dev Neurobiol. 2015 Feb 27. doi: 10.1002/dneu.22282. [Epub ahead of print].

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