You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis

Authors:
Gao L, Li D, Ma K, Zhang W, Xu T, Fu C, Jing C, Jia X, Wu S, Sun X, Dong M, Deng M, Chen Y, Shu W, Penf J, Wan F, Zhou Y, Zon LI, Pan W
Citation:
PLoS Genet. 2015;11(7): e1005346. doi:10.1371/journal.pgen.1005346
Epub:
Not Epub
Abstract:
In vertebrate definitive hematopoiesis, nascent hematopoietic stem/progenitor cells (HSPCs) migrate to and reside in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gao L, Li D, Ma K, Zhang W, Xu T, Fu C, Jing C, Jia X, Wu S, Sun X, Dong M, Deng M, Chen Y, Shu W, Penf J, Wan F, Zhou Y, Zon LI, Pan W. TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis. PLoS Genet. 2015;11(7): e1005346. doi:10.1371/journal.pgen.1005346.

RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells

Authors:
Hoeppner LH, Sinha S, Wang Y, Bhattacharya R, Dutta S, Gong X, Bedell VM, Suresh S, Chun CZ, Ramchandran R, Ekker SC, Mukhopadhyay D
Citation:
J Cell Sci. 2015;[Epub ahead of print] doi:10.1242/jcs.167601
Epub:
Yes
Abstract:
Vasculogenesis and angiogenesis are controlled by vascular permeability factor/vascular endothelial growth factor A (VEGF)....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish keratocytes
Citation Extract:
Hoeppner LH, Sinha S, Wang Y, Bhattacharya R, Dutta S, Gong X, Bedell VM, Suresh S, Chun CZ, Ramchandran R, Ekker SC, Mukhopadhyay D. RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells. J Cell Sci. 2015;[Epub ahead of print] doi:10.1242/jcs.167601 .

Tinkering signaling pathways by gain and loss of protein isoforms: the case of the EDA pathway regulator EDARADD

Authors:
Sadier A, Lambert E, Chevret P, Décimo D, Sémon M, Tohmé M, Ruggiero F, Ohlmann T, Pantalacci S, Laudet V
Citation:
BMC Evol Bio. 2015;15:129 doi:10.1186/s12862-015-0395-0
Epub:
Not Epub
Abstract:
Background: Only a handful of signaling pathways are major actors of development and responsible for both the conservation and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sadier A, Lambert E, Chevret P, Décimo D, Sémon M, Tohmé M, Ruggiero F, Ohlmann T, Pantalacci S, Laudet V. Tinkering signaling pathways by gain and loss of protein isoforms: the case of the EDA pathway regulator EDARADD. BMC Evol Bio. 2015;15:129 doi:10.1186/s12862-015-0395-0.

Agents Which Inhibit NF-κB Signaling Block Spontaneous Contractile Activity and Negatively Influence Survival of Developing Myotubes

Authors:
Carlson CG, Stein L, Dole E, Potter RM, Bayless D
Citation:
J Cell Physiol. 2015 Jun 30. doi: 10.1002/jcp.25085. [Epub ahead of print]
Epub:
Yes
Abstract:
Inhibiting the NF-κB signaling pathway provides morphological and functional benefits for the mdx mouse, a model for Duchenne...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: murine primary myotubes
Citation Extract:
Carlson CG, Stein L, Dole E, Potter RM, Bayless D. Agents Which Inhibit NF-κB Signaling Block Spontaneous Contractile Activity and Negatively Influence Survival of Developing Myotubes. J Cell Physiol. 2015 Jun 30. doi: 10.1002/jcp.25085. [Epub ahead of print].

The wound inflammatory response exacerbates growth of pre‐neoplastic cells and progression to cancer

Authors:
Antonio N, Bønnelykke‐Behrndtz ML, Ward LC, Collin J, Christensen IJ, Steiniche T, Schmidt H, Feng Y, Martin P
Citation:
EMBO J. 2015;[Epub ahead of print] doi:10.15252/embj.201490147
Epub:
Yes
Abstract:
There is a long‐standing association between wound healing and cancer, with cancer often described as a “wound that does not...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Antonio N, Bønnelykke‐Behrndtz ML, Ward LC, Collin J, Christensen IJ, Steiniche T, Schmidt H, Feng Y, Martin P. The wound inflammatory response exacerbates growth of pre‐neoplastic cells and progression to cancer. EMBO J. 2015;[Epub ahead of print] doi:10.15252/embj.201490147.

Spinal muscular atrophy phenotype is ameliorated in human motor neurons by SMN increase via different novel RNA therapeutic approaches

Authors:
Nizzardo M, Simone C, Dametti S, Salani S, Ulzi G, Pagliarani S, Rizzo F, Frattini E, Pagani F, Bresolin N, Comi G, Corti S
Citation:
Sci Rep. 2015 Jun 30;5:11746. doi: 10.1038/srep11746
Epub:
Not Epub
Abstract:
Spinal muscular atrophy (SMA) is a primary genetic cause of infant mortality due to mutations in the Survival Motor Neuron (SMN...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: motor neurons and induced pluripotent stam cells (iPSC)
Citation Extract:
Nizzardo M, Simone C, Dametti S, Salani S, Ulzi G, Pagliarani S, Rizzo F, Frattini E, Pagani F, Bresolin N, Comi G, Corti S. Spinal muscular atrophy phenotype is ameliorated in human motor neurons by SMN increase via different novel RNA therapeutic approaches. Sci Rep. 2015 Jun 30;5:11746. doi: 10.1038/srep11746.

Neural crest migration is driven by a few trailblazer cells with a unique molecular signature narrowly confined to the invasive front

Authors:
McLennan R, Schumacher LJ, Morrison JA, Teddy JM, Ridenour DA, Box AC, Semerad CL, Li H, McDowell W, Kay D, Maini PK, Baker RE, Kulesa PM
Citation:
Development. 2015 Jun 1;142(11):2014-25. doi: 10.1242/dev.117507. Epub 2015 May 14
Epub:
Not Epub
Abstract:
Neural crest (NC) cell migration is crucial to the formation of peripheral tissues during vertebrate development. However, how...
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
McLennan R, Schumacher LJ, Morrison JA, Teddy JM, Ridenour DA, Box AC, Semerad CL, Li H, McDowell W, Kay D, Maini PK, Baker RE, Kulesa PM. Neural crest migration is driven by a few trailblazer cells with a unique molecular signature narrowly confined to the invasive front. Development. 2015 Jun 1;142(11):2014-25. doi: 10.1242/dev.117507. Epub 2015 May 14.

BMP signalling controls the construction of vertebrate mucociliary epithelia

Authors:
Cibois M, Luxardi G, Chevalier B, Thomé V, Mercey O, Zaragosi LE, Barbry P, Pasini A, Marcet B, Kodjabachian L
Citation:
Development. 2015 Jun 19. pii: dev.118679. [Epub ahead of print]
Epub:
Yes
Abstract:
Despite the importance of mucociliary epithelia in animal physiology, the mechanisms controlling their establishment are poorly...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Cibois M, Luxardi G, Chevalier B, Thomé V, Mercey O, Zaragosi LE, Barbry P, Pasini A, Marcet B, Kodjabachian L. BMP signalling controls the construction of vertebrate mucociliary epithelia. Development. 2015 Jun 19. pii: dev.118679. [Epub ahead of print].

MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell–cell junctions in epithelial cells

Authors:
Breznau EB, Semack AC, Higashi T, Miller AL
Citation:
Mol Biol Cell. 2015;26:13 2439-2455. doi:10.1091/mbc.E14-11-1553
Epub:
Not Epub
Abstract:
Localized activation of Rho GTPases is essential for multiple cellular functions, including cytokinesis and formation and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Breznau EB, Semack AC, Higashi T, Miller AL. MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell–cell junctions in epithelial cells. Mol Biol Cell. 2015;26:13 2439-2455. doi:10.1091/mbc.E14-11-1553.

The Wnt Co-Receptor Lrp5 Is Required for Cranial Neural Crest Cell Migration in Zebrafish

Authors:
Willems B, Tao S, Yu T, Huysseune A, Witten PE, Winkler C
Citation:
PLoS ONE. 2015;10(6):e0131768. doi:10.1371/journal.pone.0131768
Epub:
Not Epub
Abstract:
During vertebrate neurulation, cranial neural crest cells (CNCCs) undergo epithelial to mesenchymal transition (EMT),...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Willems B, Tao S, Yu T, Huysseune A, Witten PE, Winkler C. The Wnt Co-Receptor Lrp5 Is Required for Cranial Neural Crest Cell Migration in Zebrafish. PLoS ONE. 2015;10(6):e0131768. doi:10.1371/journal.pone.0131768.

Pages