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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
A Boolean Function for Neural Induction Reveals a Critical Role of Direct Intercellular Interactions in Patterning the Ectoderm of the Ascidian Embryo
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Citation:
PLoS Comput Biol. 2015 Dec 29;11(12):e1004687. doi: 10.1371/journal.pcbi.1004687. eCollection 2015 Dec Epub:
Not Epub Abstract:
A complex system of multiple signaling molecules often produce differential gene expression patterns in animal embryos. In the... Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis (ascidian) Citation Extract: Ohta N, Waki K, Mochizuki A, Satou Y. A Boolean Function for Neural Induction Reveals a Critical Role of Direct Intercellular Interactions in Patterning the Ectoderm of the Ascidian Embryo. PLoS Comput Biol. 2015 Dec 29;11(12):e1004687. doi: 10.1371/journal.pcbi.1004687. eCollection 2015 Dec. |
Deltex1 is inhibited by the Notch-Hairy/E(Spl) signaling pathway and induces neuronal and glial differentiation
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Citation:
Neural Dev. 2015 Dec 30;10(1):28. doi: 10.1186/s13064-015-0055-5 Epub:
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BACKGROUND: Notch signaling has been conserved throughout evolution and plays a fundamental role in various neural... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cheng YC, Huang YC, Yeh TH, Shih HY, Lin CY, Lin SJ, Chiu CC, Huang CW, Jiang YJ. Deltex1 is inhibited by the Notch-Hairy/E(Spl) signaling pathway and induces neuronal and glial differentiation. Neural Dev. 2015 Dec 30;10(1):28. doi: 10.1186/s13064-015-0055-5. |
A novel role for ASCL1 in the regulation of mesendoderm formation via HDAC-dependent antagonism of VegT function
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Development. 2015;[Epub ahead of print] doi:10.1242/dev.126292 Epub:
Yes Abstract:
Maternally expressed proteins function in vertebrates to establish the major body axes of the embryo, and to establish a pre-... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Gao L, Zhu X, Chen G, Ma X, Zhang Y, Khand AA, Shi H, Gu F, Lin H, Chen Y, Zhang H, He L, Tao Q. A novel role for ASCL1 in the regulation of mesendoderm formation via HDAC-dependent antagonism of VegT function. Development. 2015;[Epub ahead of print] doi:10.1242/dev.126292 . |
Recessive mutations in the α3 (VI) collagen gene COL6A3 cause early-onset isolated dystonia
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Citation:
Am J Hum Genet. 2015 Jun 4;96(6):883-93. doi: 10.1016/j.ajhg.2015.04.010. Epub 2015 May 21 Epub:
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Isolated dystonia is a disorder characterized by involuntary twisting postures arising from sustained muscle contractions.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zech M, Lam DD, Francescatto L, Schormair B, Salminen AV, Jochim A, Wieland T, Lichtner P, Peters A, Gieger C, Lochmüller H, Strom TM, Haslinger B, Katsanis N, Winkelmann J. Recessive mutations in the α3 (VI) collagen gene COL6A3 cause early-onset isolated dystonia. Am J Hum Genet. 2015 Jun 4;96(6):883-93. doi: 10.1016/j.ajhg.2015.04.010. Epub 2015 May 21. |
Genetic pathways for differentiation of the peripheral nervous system in ascidians
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Nat Commun. 2015 Oct 30;6:8719. doi: 10.1038/ncomms9719 Epub:
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Ascidians belong to tunicates, the sister group of vertebrates. Peripheral nervous systems (PNSs) including epidermal sensory... Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis (ascidian) Citation Extract: Waki K, Imai KS, Satou Y. Genetic pathways for differentiation of the peripheral nervous system in ascidians. Nat Commun. 2015 Oct 30;6:8719. doi: 10.1038/ncomms9719. |
Discovery, Synthesis, and Optimization of Diarylisoxazole-3-carboxamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore
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ChemMedChem. 2015 Oct;10(10):1655-71. doi: 10.1002/cmdc.201500284. Epub 2015 Aug 18 Epub:
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The mitochondrial permeability transition pore (mtPTP) is a Ca2+-requiring mega-channel which, under pathological conditions,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Roy S, Šileikytė J, Schiavone M, Neuenswander B, Argenton F, Aubé J, Hedrick MP, Chung TD, Forte MA, Bernardi P, Schoenen FJ. Discovery, Synthesis, and Optimization of Diarylisoxazole-3-carboxamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore. ChemMedChem. 2015 Oct;10(10):1655-71. doi: 10.1002/cmdc.201500284. Epub 2015 Aug 18. |
A susceptibility locus rs7099208 is associated with non-obstructive azoospermia via reduction in the expression of FAM160B1
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Citation:
J Biomed Res. 2015 Nov;29(6):491-500. doi: 10.7555/JBR.29.20150034. Epub 2015 Aug 8. Erratum in: J Biomed Res. 2015 Nov;29(6):518 Epub:
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Non-obstructive azoospermia (NOA) is a severe defect in male reproductive health that occurs in 1% of adult men. In a previous... Organism or Cell Type:
cell culture: mouse spermatocyte GC2-spd Citation Extract: Zhang Y, Qian J, Wu M, Liu M, Zhang K, Lin Y, Guo X, Zhou Z, Hu Z, Sha J. A susceptibility locus rs7099208 is associated with non-obstructive azoospermia via reduction in the expression of FAM160B1. J Biomed Res. 2015 Nov;29(6):491-500. doi: 10.7555/JBR.29.20150034. Epub 2015 Aug 8. Erratum in: J Biomed Res. 2015 Nov;29(6):518. |
ZBTB42 mutation defines a novel lethal congenital contracture syndrome (LCCS6)
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Citation:
Hum Mol Genet. 2014 Dec 15;23(24):6584-93. doi: 10.1093/hmg/ddu384. Epub 2014 Jul 23 Epub:
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Lethal congenital contracture syndrome (LCCS) is a lethal autosomal recessive form of arthrogryposis multiplex congenita (AMC... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Patel N, Smith LL, Faqeih E, Mohamed J, Gupta VA, Alkuraya FS. ZBTB42 mutation defines a novel lethal congenital contracture syndrome (LCCS6). Hum Mol Genet. 2014 Dec 15;23(24):6584-93. doi: 10.1093/hmg/ddu384. Epub 2014 Jul 23. |
The PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway
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Citation:
J Biol Chem. 2015 Dec 18;290(51):30562-72. doi: 10.1074/jbc.M115.697615. Epub 2015 Oct 23 Epub:
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The non-canonical WNT/planar cell polarity (WNT/PCP) pathway plays important roles in morphogenetic processes in vertebrates.... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Martinez S, Scerbo P, Giordano M, Daulat AM, Lhoumeau AC, Thomé V, Kodjabachian L, Borg JP. The PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway. J Biol Chem. 2015 Dec 18;290(51):30562-72. doi: 10.1074/jbc.M115.697615. Epub 2015 Oct 23. |
Safety and pharmacokinetic profile of eteplirsen, SRP-4045, and SRP-4053, three phosphorodiamidate morpholino oligomers (PMOs) for the treatment of patients with Duchenne muscular dystrophy (DMD)
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Citation:
Neuromusc Dis. 2014. 24(9-10):828. doi:10.1016/j.nmd.2014.06.124 Epub:
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Eteplirsen, SRP-4045 and SRP-4053 are three PMOs developed as treatments for DMD. DMD is mostly caused by mutations in the... Delivery Method:
iv infusion Organism or Cell Type:
Nonhuman primate, human Citation Extract: Sazani P, Magee T, Charleston JS, Shanks C, Zhang J, Carver M, Rodino-Klapac L, Sahenk Z, Roush K, Bird L, Lowes LP, Alfano L, Gomez AM, Lewis S, Malik V, Shontz K, Flanigan K, Shilling C, Bhalli J, Kaur H, Walisser J, Forget J, Saoud J, Mendell JR, Kaye E
. Safety and pharmacokinetic profile of eteplirsen, SRP-4045, and SRP-4053, three phosphorodiamidate morpholino oligomers (PMOs) for the treatment of patients with Duchenne muscular dystrophy (DMD). Neuromusc Dis. 2014. 24(9-10):828. doi:10.1016/j.nmd.2014.06.124. |