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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Deletion of Dystrophin In-Frame Exon 5 Leads to a Severe Phenotype: Guidance for Exon Skipping Strategies

Authors:
Toh ZY, Thandar Aung-Htut M, Pinniger G, Adams AM, Krishnaswarmy S, Wong BL, Fletcher S, Wilton SD
Citation:
PLoS One. 2016 Jan 8;11(1):e0145620. doi: 10.1371/journal.pone.0145620. eCollection 2016
Epub:
Not Epub
Abstract:
Duchenne and Becker muscular dystrophy severity depends upon the nature and location of the DMD gene lesion and generally...
Delivery Method:
peptide-linked
Organism or Cell Type:
mice
Citation Extract:
Toh ZY, Thandar Aung-Htut M, Pinniger G, Adams AM, Krishnaswarmy S, Wong BL, Fletcher S, Wilton SD. Deletion of Dystrophin In-Frame Exon 5 Leads to a Severe Phenotype: Guidance for Exon Skipping Strategies. PLoS One. 2016 Jan 8;11(1):e0145620. doi: 10.1371/journal.pone.0145620. eCollection 2016.

Identifying Regulators of Morphogenesis Common to Vertebrate Neural Tube Closure and Caenorhabditis elegans Gastrulation

Authors:
Sullivan-Brown JL, Tandon P, Bird KE, Dickinson DJ, Tintori SC, Heppert JK, Meserve JH, Trogden KP, Orlowski SK, Conlon FL, Goldstein B
Citation:
Genetics. 2016 Jan;202(1):123-39. doi: 10.1534/genetics.115.183137. Epub 2015 Oct 4
Epub:
Not Epub
Abstract:
Neural tube defects including spina bifida are common and severe congenital disorders. In mice, mutations in more than 200...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Sullivan-Brown JL, Tandon P, Bird KE, Dickinson DJ, Tintori SC, Heppert JK, Meserve JH, Trogden KP, Orlowski SK, Conlon FL, Goldstein B. Identifying Regulators of Morphogenesis Common to Vertebrate Neural Tube Closure and Caenorhabditis elegans Gastrulation. Genetics. 2016 Jan;202(1):123-39. doi: 10.1534/genetics.115.183137. Epub 2015 Oct 4.

PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress

Authors:
Kuo ML, Lee MB, Tang M, den Besten W, Hu S, Sweredoski MJ, Hess S, Chou CM, Changou CA, Su M, Jia W, Su L, Yen Y
Citation:
Sci Rep. 2016 Jan 6;6:18846. doi: 10.1038/srep18846
Epub:
Not Epub
Abstract:
Ribonucleotide reductase small subunit B (RRM2B) is a stress response protein that protects normal human fibroblasts from...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kuo ML, Lee MB, Tang M, den Besten W, Hu S, Sweredoski MJ, Hess S, Chou CM, Changou CA, Su M, Jia W, Su L, Yen Y. PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress. Sci Rep. 2016 Jan 6;6:18846. doi: 10.1038/srep18846.

Visualization of Assembly Intermediates and Budding Vacuoles of Singapore Grouper Iridovirus in Grouper Embryonic Cells

Authors:
Liu Y, Tran BN, Wang F, Ounjai P, Wu J, Hew CL
Citation:
Sci Rep. 2016 Jan 4;6:18696. doi: 10.1038/srep18696
Epub:
Not Epub
Abstract:
Iridovirid infection is associated with the catastrophic loss in aquaculture industry and the population decline of wild...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: Grouper embryonic cells (GECs) from Epinephelus tauvina
Citation Extract:
Liu Y, Tran BN, Wang F, Ounjai P, Wu J, Hew CL. Visualization of Assembly Intermediates and Budding Vacuoles of Singapore Grouper Iridovirus in Grouper Embryonic Cells. Sci Rep. 2016 Jan 4;6:18696. doi: 10.1038/srep18696.

Cdx4 and Retinoic Acid Interact to Position the Hindbrain-Spinal Cord Transition

Authors:
Chang J, Skromne I, Ho RK
Citation:
Dev Biol. 2016;[Epub ahead of print] doi:10.1016/j.ydbio.2015.12.025
Epub:
Yes
Abstract:
The sub-division of the posterior-most territory of the neural plate results in the formation of two distinct neural structures...
Organism or Cell Type:
zebrafish
Citation Extract:
Chang J, Skromne I, Ho RK. Cdx4 and Retinoic Acid Interact to Position the Hindbrain-Spinal Cord Transition. Dev Biol. 2016;[Epub ahead of print] doi:10.1016/j.ydbio.2015.12.025.

The AP-1 transcription factor component Fosl2 potentiates the rate of myocardial differentiation from the zebrafish second heart field

Authors:
Jahangiri L, Sharpe M, Novikov N, González-Rosa JM, Borikova A, Nevis K, Paffett-Lugassy N, Zhao L, Adams M, Guner-Ataman B, Burns CE, Burns CG
Citation:
Development. 2016 Jan 1;143(1):113-22. doi: 10.1242/dev.126136
Epub:
Not Epub
Abstract:
The vertebrate heart forms through successive phases of cardiomyocyte differentiation. Initially, cardiomyocytes derived from...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jahangiri L, Sharpe M, Novikov N, González-Rosa JM, Borikova A, Nevis K, Paffett-Lugassy N, Zhao L, Adams M, Guner-Ataman B, Burns CE, Burns CG. The AP-1 transcription factor component Fosl2 potentiates the rate of myocardial differentiation from the zebrafish second heart field. Development. 2016 Jan 1;143(1):113-22. doi: 10.1242/dev.126136.

A co-culture assay of embryonic zebrafish hearts to assess migration of epicardial cells in vitro

Authors:
Yue MS, Plavicki JS, Li XY, Peterson RE, Heideman W
Citation:
BMC Dev Biol. 2015 Dec 29;15(1):50. doi: 10.1186/s12861-015-0100-y
Epub:
Not Epub
Abstract:
BACKGROUND: The vertebrate heart consists of three cell layers: the innermost endothelium, the contractile myocardium and the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yue MS, Plavicki JS, Li XY, Peterson RE, Heideman W. A co-culture assay of embryonic zebrafish hearts to assess migration of epicardial cells in vitro. BMC Dev Biol. 2015 Dec 29;15(1):50. doi: 10.1186/s12861-015-0100-y.

Methyl-CpG Binding Protein 2 (Mecp2) Regulates Sensory Function Through Sema5b and Robo2

Authors:
Leong WY, Lim ZH, Korzh V, Pietri T, Goh EL
Citation:
Front Cell Neurosci. 2015 Dec 21;9:481. doi: 10.3389/fncel.2015.00481. eCollection 2015
Epub:
Not Epub
Abstract:
Mutations in the gene encoding the MECP2 underlies Rett syndrome, a neurodevelopmental disorder in young females. Although...
Organism or Cell Type:
zebrafish
Citation Extract:
Leong WY, Lim ZH, Korzh V, Pietri T, Goh EL. Methyl-CpG Binding Protein 2 (Mecp2) Regulates Sensory Function Through Sema5b and Robo2. Front Cell Neurosci. 2015 Dec 21;9:481. doi: 10.3389/fncel.2015.00481. eCollection 2015.

Regulatory circuit rewiring and functional divergence of the duplicate admp genes in dorsoventral axial patterning

Authors:
Chang YC, Pai CY, Chen YC, Ting HC, Martinez P, Telford MJ, Yu JK, Su YH
Citation:
Dev Biol. 2015 Dec 21. pii: S0012-1606(15)30365-1. doi: 10.1016/j.ydbio.2015.12.015. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The spatially opposed expression of Antidorsalizing morphogenetic protein (Admp) and BMP signals controls dorsoventral (DV)...
Organism or Cell Type:
Sea urchin
Citation Extract:
Chang YC, Pai CY, Chen YC, Ting HC, Martinez P, Telford MJ, Yu JK, Su YH. Regulatory circuit rewiring and functional divergence of the duplicate admp genes in dorsoventral axial patterning. Dev Biol. 2015 Dec 21. pii: S0012-1606(15)30365-1. doi: 10.1016/j.ydbio.2015.12.015. [Epub ahead of print].

Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression

Authors:
Anderson H, Patch TC, Reddy PN, Hagedorn EJ, Kim PG, Soltis KA, Chen MJ, Tamplin OJ, Frye M, MacLean GA, Hübner K, Bauer DE, Kanki JP, Vogin G, Huston NC, Nguyen M, Fujiwara Y, Paw BH, Vestweber D, Zon LI, Orkin SH, Daley GQ, Shah DI
Citation:
Blood. 2015 Dec 24;126(26):2811-20. doi: 10.1182/blood-2015-07-659276. Epub 2015 Sep 18
Epub:
Not Epub
Abstract:
Rare endothelial cells in the aorta-gonad-mesonephros (AGM) transition into hematopoietic stem cells (HSCs) during embryonic...
Organism or Cell Type:
zebrafish
Citation Extract:
Anderson H, Patch TC, Reddy PN, Hagedorn EJ, Kim PG, Soltis KA, Chen MJ, Tamplin OJ, Frye M, MacLean GA, Hübner K, Bauer DE, Kanki JP, Vogin G, Huston NC, Nguyen M, Fujiwara Y, Paw BH, Vestweber D, Zon LI, Orkin SH, Daley GQ, Shah DI. Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression. Blood. 2015 Dec 24;126(26):2811-20. doi: 10.1182/blood-2015-07-659276. Epub 2015 Sep 18.

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