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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

ITGBL1 modulates integrin activity to promote cartilage formation and protect against arthritis

Authors:
Song EK, Jeon J, Jang DG, Kim HE, Sim HJ, Kwon KY, Medina-Ruiz S, Jang H-J, Lee AR, Rho JG, Lee H-S, Kim SJ, Park CY, Myung K, Kim W, Kwon T, Yang S, Park TJ
Citation:
Sci Translat Med. 2018;10(462):eaam7486 doi:10.1126/scitranslmed.aam7486
Epub:
Not Epub
Abstract:
Developing and mature chondrocytes constantly interact with and remodel the surrounding extracellular matrix (ECM). Recent...
Link:
http://stm.sciencemag.org/content/10/462/eaam7486
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Song EK, Jeon J, Jang DG, Kim HE, Sim HJ, Kwon KY, Medina-Ruiz S, Jang H-J, Lee AR, Rho JG, Lee H-S, Kim SJ, Park CY, Myung K, Kim W, Kwon T, Yang S, Park TJ. ITGBL1 modulates integrin activity to promote cartilage formation and protect against arthritis. Sci Translat Med. 2018;10(462):eaam7486 doi:10.1126/scitranslmed.aam7486 .

Evaluation of the estrogen receptor alpha as a possible target of bifenthrin effects in the estrogenic and dopaminergic signaling pathways in zebrafish embryos

Authors:
Becker Bertotto L, Dasgupta S, Vliet S, Dudley S, Gan J, Volz DC, Schlenk D
Citation:
Sci Total Environ. 2019;651(pt.2):2424-2431. doi:10.1016/j.scitotenv.2018.10.079
Epub:
Not Epub
Abstract:
Bifenthrin (BF) is a pyrethroid insecticide widely used in urban and agricultural applications. Previous studies in embryos of...
Link:
https://www.sciencedirect.com/science/article/pii/S0048969718339524
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Becker Bertotto L, Dasgupta S, Vliet S, Dudley S, Gan J, Volz DC, Schlenk D. Evaluation of the estrogen receptor alpha as a possible target of bifenthrin effects in the estrogenic and dopaminergic signaling pathways in zebrafish embryos. Sci Total Environ. 2019;651(pt.2):2424-2431. doi:10.1016/j.scitotenv.2018.10.079.

CAV1 regulates primordial follicle formation via the Notch2 signalling pathway and is associated with premature ovarian insufficiency in humans

Authors:
Huang K, Dang Y, Zhang P, Shen C, Sui X, Xia G, Qin Y, Jiao X, Wang C, Huo R, Chen Z-J
Citation:
Hum Reprod. 2018;dey299. doi:10.1093/humrep/dey299
Epub:
Not Epub
Abstract:
STUDY QUESTION: What is the function of CAV1 in folliculogenesis and female reproduction? SUMMARY ANSWER: CAV1 regulates...
Link:
https://academic.oup.com/humrep/advance-article-abstract/doi/10.1093/humrep/dey299/5124569
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse ovary
Citation Extract:
Huang K, Dang Y, Zhang P, Shen C, Sui X, Xia G, Qin Y, Jiao X, Wang C, Huo R, Chen Z-J. CAV1 regulates primordial follicle formation via the Notch2 signalling pathway and is associated with premature ovarian insufficiency in humans. Hum Reprod. 2018;dey299. doi:10.1093/humrep/dey299.

The Ric-8A/Gα13/FAK signaling cascade controls focal adhesion formation during neural crest cell migration

Authors:
Toro-Tapia G, Villaseca S, Beyer A, Roycroft A, Marcellini S, Mayor R, Torrejón M
Citation:
Development. 2018 Oct 8. pii: dev.164269. doi: 10.1242/dev.164269. [Epub ahead of print]
Epub:
Yes
Abstract:
Ric-8A is a pleiotropic guanine nucleotide exchange factor involved the activation of various heterotrimeric G protein pathways...
Link:
http://dev.biologists.org/content/early/2018/10/05/dev.164269.long
Citation Extract:
Toro-Tapia G, Villaseca S, Beyer A, Roycroft A, Marcellini S, Mayor R, Torrejón M. The Ric-8A/Gα13/FAK signaling cascade controls focal adhesion formation during neural crest cell migration. Development. 2018 Oct 8. pii: dev.164269. doi: 10.1242/dev.164269. [Epub ahead of print].

Generation of animal form by the Chordin/Tolloid/BMP gradient: 100 years after D'Arcy Thompson

Authors:
De Robertis EM, Moriyama Y, Colozza G
Citation:
Dev Growth Differ. 2017 Sep;59(7):580-592. doi: 10.1111/dgd.12388. Epub 2017 Aug 16
Epub:
Not Epub
Abstract:
The classic book "On Growth and Form" by naturalist D'Arcy Thompson was published 100 years ago. To celebrate...
Link:
https://onlinelibrary.wiley.com/doi/pdf/10.1111/dgd.12388
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
De Robertis EM, Moriyama Y, Colozza G. Generation of animal form by the Chordin/Tolloid/BMP gradient: 100 years after D'Arcy Thompson. Dev Growth Differ. 2017 Sep;59(7):580-592. doi: 10.1111/dgd.12388. Epub 2017 Aug 16.

The Evolutionarily Conserved Cassette Exon 7b Drives ERG's Oncogenic Properties

Authors:
Jumbe SL, Porazinski SR, Oltean S, Mansell JP, Vahabi B, Wilson ID, Ladomery MR
Citation:
Transl Oncol. 2018;12(1):134-42. doi:10.1016/j.tranon.2018.09.001
Epub:
Not Epub
Abstract:
The oncogene ERG encodes an ETS family transcription factor and is implicated in blood, vascular, and bone development and in...
Link:
https://www.sciencedirect.com/science/article/pii/S1936523318303553
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: MG63 ( human osteoblast-like osteosarcoma) and VCaP (human prostate cancer vertebral metastasis)
Citation Extract:
Jumbe SL, Porazinski SR, Oltean S, Mansell JP, Vahabi B, Wilson ID, Ladomery MR. The Evolutionarily Conserved Cassette Exon 7b Drives ERG's Oncogenic Properties. Transl Oncol. 2018;12(1):134-42. doi:10.1016/j.tranon.2018.09.001.

Intestinal microbiome adjusts the innate immune setpoint during colonization through negative regulation of MyD88

Authors:
Koch BEV, Yang S, Lamers G, Stougaard J, Spaink HP
Citation:
Nat Commun. 2018 Oct 5;9(1):4099. doi: 10.1038/s41467-018-06658-4
Epub:
Not Epub
Abstract:
Host pathways mediating changes in immune states elicited by intestinal microbial colonization are incompletely characterized....
Link:
https://www.nature.com/articles/s41467-018-06658-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Koch BEV, Yang S, Lamers G, Stougaard J, Spaink HP. Intestinal microbiome adjusts the innate immune setpoint during colonization through negative regulation of MyD88. Nat Commun. 2018 Oct 5;9(1):4099. doi: 10.1038/s41467-018-06658-4.

Fam46a regulates BMP-dependent pre-placodal ectoderm differentiation in Xenopus

Authors:
Watanabe T, Yamamoto T, Tsukano K, Hirano S, Horikawa A, Michiue T
Citation:
Development. 2018:dev.166710 doi: 10.1242/dev.166710
Epub:
Not Epub
Abstract:
The pre-placodal ectoderm (PPE) is a specialized ectodermal region which gives rise to the sensory organs and other systems....
Link:
dev.biologists.org/content/early/2018/10/04/dev.166710
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Watanabe T, Yamamoto T, Tsukano K, Hirano S, Horikawa A, Michiue T. Fam46a regulates BMP-dependent pre-placodal ectoderm differentiation in Xenopus. Development. 2018:dev.166710 doi: 10.1242/dev.166710.

4.1Ba is necessary for glutamatergic synapse formation in the sensorimotor circuit of developing zebrafish

Authors:
Fierro J Jr, Haynes DR, Washbourne P
Citation:
PLoS One. 2018 Oct 4;13(10):e0205255. doi: 10.1371/journal.pone.0205255
Epub:
Not Epub
Abstract:
During the process of synapse formation, thousands of proteins assemble at prospective sites of cell-cell communication....
Link:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205255
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fierro J Jr, Haynes DR, Washbourne P. 4.1Ba is necessary for glutamatergic synapse formation in the sensorimotor circuit of developing zebrafish. PLoS One. 2018 Oct 4;13(10):e0205255. doi: 10.1371/journal.pone.0205255.

CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii

Authors:
Lykins JD, Filippova EV, Halavaty AS, Minasov G, Zhou Y, Dubrovska I, Flores KJ, Ludmilla A Shuvalova LA, Ruan J, El Bissati K, Dovgin S, Roberts CW, Woods S, Moulton JD, Moulton H, McPhillie M, Muench SP, Fishwick CWG, Sabini E, Shanmugam D, Roos DS, McLeod R, Anderson WF, Ngô H
Citation:
Front Cell Infect Microbiol. 2018;[Epub] doi:10.3389/fcimb.2018.00352
Epub:
Yes
Abstract:
Toxoplasma gondii, an Apicomplexan parasite, causes significant morbidity and mortality, including severe disease in...
Link:
https://www.frontiersin.org/articles/10.3389/fcimb.2018.00352/full
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Toxoplasma gondii (Apicomplexan)
Citation Extract:
Lykins JD, Filippova EV, Halavaty AS, Minasov G, Zhou Y, Dubrovska I, Flores KJ, Ludmilla A Shuvalova LA, Ruan J, El Bissati K, Dovgin S, Roberts CW, Woods S, Moulton JD, Moulton H, McPhillie M, Muench SP, Fishwick CWG, Sabini E, Shanmugam D, Roos DS, McLeod R, Anderson WF, Ngô H. CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii. Front Cell Infect Microbiol. 2018;[Epub] doi:10.3389/fcimb.2018.00352.

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