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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
TMPRSS2 is the major activating protease of influenza A virus in primary human airway cells and influenza B virus in human type II pneumocytes
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Citation:
J Virol. 2019 Oct 15;93(21):e00649-19. doi: 10.1128/JVI.00649-19. PMID: 31391268; PMCID: PMC6803253 Epub:
Yes Abstract:
Cleavage of influenza virus hemagglutinin (HA) by host cell proteases is essential for virus infectivity and spread. We... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: primary human bronchial epithelial cells (HBEC), primary type II alveolar epithelial cells (AECII) and Calu-3 cells Citation Extract: Limburg H, Harbig A, Bestle D, Stein DA, Moulton HM, Jaeger J, Janga H, Hardes K, Koepke J, Schulte L, Koczulla AR, Schmeck B, Klenk HD, Böttcher-Friebertshäuser E. TMPRSS2 is the major activating protease of influenza A virus in primary human airway cells and influenza B virus in human type II pneumocytes. J Virol. 2019 Oct 15;93(21):e00649-19. doi: 10.1128/JVI.00649-19. PMID: 31391268; PMCID: PMC6803253. |
Zebrafish Dynamin is required for maintenance of enveloping layer integrity and the progression of epiboly
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Citation:
Dev Biol. 2014 Jan 1;385(1):52-66. doi: 10.1016/j.ydbio.2013.10.015. Epub 2013 Oct 24 Epub:
Not Epub Abstract:
Epiboly, the first morphogenetic cell movement that occurs in the zebrafish embryo, is the process by which the blastoderm... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lepage SE, Tada M, Bruce AE. Zebrafish Dynamin is required for maintenance of enveloping layer integrity and the progression of epiboly. Dev Biol. 2014 Jan 1;385(1):52-66. doi: 10.1016/j.ydbio.2013.10.015. Epub 2013 Oct 24. |
Efficient generation of zebrafish maternal-zygotic mutants through transplantation of ectopically induced and Cas9/gRNA targeted PGCs
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Citation:
bioRxiv. 2019:[preprint] doi:10.1101/693853 Epub:
Not Epub Abstract:
The CRISPR/Cas9 technology has been widely utilized for knocking out genes involved in various biological processes in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang F, Li X, He M, Ye D, Xiong F, Amin G, Zhu Z, Sun Y. Efficient generation of zebrafish maternal-zygotic mutants through transplantation of ectopically induced and Cas9/gRNA targeted PGCs. bioRxiv. 2019:[preprint] doi:10.1101/693853 . |
Evolution of abbreviated development in Heliocidaris erythrogramma dramatically re-wired the highly conserved sea urchin developmental gene regulatory network to decouple signaling center function from ultimate fate
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Citation:
bioRxiv. 2019:[preprint] doi:10.1101/712216 Epub:
Not Epub Abstract:
Developmental gene regulatory networks (GRNs) describe the interactions among gene products that drive the differential... Delivery Method:
microinjection Organism or Cell Type:
Heliocidaris erythrogramma (sea urchin) Citation Extract: Edgar A, Byrnev M, McClay DR, Wray GA. Evolution of abbreviated development in Heliocidaris erythrogramma dramatically re-wired the highly conserved sea urchin developmental gene regulatory network to decouple signaling center function from ultimate fate. bioRxiv. 2019:[preprint] doi:10.1101/712216. |
Gclc deletion in surface-ectoderm tissues induces microphthalmia
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Citation:
bioRxiv. 2019:[preprint]. doi:10.1101/700591 Epub:
Not Epub Abstract:
Glutamate cysteine ligase catalytic subunit (Gclc) is the catalytic subunit for the glutamate-cysteine ligase (Gcl) enzyme. Gcl... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Thompson B, Chen Y, Philippe J, Anderson D, Golla JP, Davidson E, Apostolopoulos N, Schey K, Katsanis N, Orlicky DJ, Thompson D, Vasiliou V. Gclc deletion in surface-ectoderm tissues induces microphthalmia. bioRxiv. 2019:[preprint]. doi:10.1101/700591. |
Planar Polarization of Cilia in the Zebrafish Floor Plate Involves Par3-Mediated Posterior Localization of Highly Motile Basal Bodies
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Citation:
bioRxiv. 2019:[preprint] doi:10.1101/702282 Epub:
Not Epub Abstract:
To produce a directional flow, ciliated epithelia display a uniform orientation of ciliary beating. Oriented beating requires... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Donati A, Schneider-Maunoury S, Vesque C. Planar Polarization of Cilia in the Zebrafish Floor Plate Involves Par3-Mediated Posterior Localization of Highly Motile Basal Bodies. bioRxiv. 2019:[preprint] doi:10.1101/702282. |
Greb1 is required for axial elongation and segmentation in vertebrate embryos
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Citation:
bioRxiv. 2019:[preprint] doi:10.1101/692095 Epub:
Not Epub Abstract:
During vertebrate embryonic development, the formation of axial structures is driven by a population of stem-like cells that... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Prajapati RS, Mitter R, Vezzaro A, Ish-Horowicz D. Greb1 is required for axial elongation and segmentation in vertebrate embryos. bioRxiv. 2019:[preprint] doi:10.1101/692095. |
Histone code dictates fate biasing of neural crest cells to melanocyte lineage
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Citation:
bioRxiv. 2019;[preprint]. doi:10.1101/702332 Epub:
Not Epub Abstract:
In the neural crest lineage, progressive fate-restriction and stem cell assignment are critical for both development and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Raja DA, Subramaniam Y, Gotherwal V, Tanwar J, Motiani R, Sivasubbu S, Gokhale RS, Natarajan VT. Histone code dictates fate biasing of neural crest cells to melanocyte lineage. bioRxiv. 2019;[preprint]. doi:10.1101/702332 . |
Intracellular enhancement of BMP signaling by LIM-domain protein FHL3 controls spatiotemporal emergence of the neural crest driven by WNT signaling
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/711192 Epub:
Not Epub Abstract:
How multiple morphogen signals are coordinated in space and time to position key embryonic tissues remains elusive. During... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Alkobtawi M, Pla P, Monsoro-Burq AH. Intracellular enhancement of BMP signaling by LIM-domain protein FHL3 controls spatiotemporal emergence of the neural crest driven by WNT signaling. bioRxiv. 2019;[preprint] doi:10.1101/711192. |
Deficiency in the endocytic adaptor protein PHETA1/2 impairs renal and craniofacial development
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/727578 Epub:
Not Epub Abstract:
A critical barrier in the treatment of endosomal and lysosomal diseases is the lack of understanding of the in vivo functions... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ates KM, Wang T, Moreland T, Veeranan-Karmegam R, Anand P, Wenzel W, Kim H-G, Wolfe LA, Stephen JA, Adams DR, Markello T, Tifft CJ, Gahl WA, Gonsalvez GB, May Christine Malicdan, Flanagan-Steet H, Pan Y. Deficiency in the endocytic adaptor protein PHETA1/2 impairs renal and craniofacial development. bioRxiv. 2019;[preprint] doi:10.1101/727578. |