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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Knock-down of Cathepsin D in zebrafish fertilized eggs determines congenital myopathy

Authors:
Follo C, Ozzano M, Montalenti C, Santoro MM, Isidoro C
Citation:
Biosci Rep. 2013;[Epub ahead of print] doi:10.1042/BSR20120100
Epub:
Not Epub
Abstract:
Cathepsin D (CD) is an ubiquitous lysosomal hydrolase involved in a variety of pathophysiological functions, including protein...
Organism or Cell Type:
zebrafish
Citation Extract:
Follo C, Ozzano M, Montalenti C, Santoro MM, Isidoro C. Knock-down of Cathepsin D in zebrafish fertilized eggs determines congenital myopathy. Biosci Rep. 2013;[Epub ahead of print] doi:10.1042/BSR20120100.

Kruppel-like factor 4 is a mediator of proinflammatory signaling in macrophages

Authors:
Feinberg MW, Cao Z, Wara AK, Lebedeva MA, Senbanerjee S, Jain MK
Citation:
J Biol Chem. 2005 Nov 18;280(46):38247-58. Epub 2005 Sep 16
Epub:
Not Epub
Abstract:
Activation of macrophages is important in chronic inflammatory disease states such as atherosclerosis. Proinflammatory...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: RAW 264.7 cells
Citation Extract:
Feinberg MW, Cao Z, Wara AK, Lebedeva MA, Senbanerjee S, Jain MK. Kruppel-like factor 4 is a mediator of proinflammatory signaling in macrophages. J Biol Chem. 2005 Nov 18;280(46):38247-58. Epub 2005 Sep 16.

Lefty antagonism of squint is essential for normal gastrulation

Authors:
Feldman B, Concha ML, Saude L, Parsons MJ, Adams RJ, Wilson SW, Stemple DL
Citation:
Curr Biol. 2002 Dec 23;12(24):2129-35
Epub:
Not Epub
Abstract:
Activities of a variety of signaling proteins that regulate embryogenesis are limited by endogenous antagonists. The zebrafish...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Feldman B, Concha ML, Saude L, Parsons MJ, Adams RJ, Wilson SW, Stemple DL. Lefty antagonism of squint is essential for normal gastrulation. Curr Biol. 2002 Dec 23;12(24):2129-35.

Live Imaging of Innate Immune Cell Sensing of Transformed Cells in Zebrafish Larvae: Parallels between Tumor Initiation and Wound Inflammation

Authors:
Feng Y, Santoriello C, Mione M, Hurlstone A, Martin P
Citation:
PLoS Biol. 2010 Dec 14;8(12):e1000562
Epub:
Not Epub
Abstract:
It has not previously been possible to live image the earliest interactions between the host environment and oncogene-...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Feng Y, Santoriello C, Mione M, Hurlstone A, Martin P. Live Imaging of Innate Immune Cell Sensing of Transformed Cells in Zebrafish Larvae: Parallels between Tumor Initiation and Wound Inflammation. PLoS Biol. 2010 Dec 14;8(12):e1000562.

Live Imaging of Tumor Initiation in Zebrafish Larvae Reveals a Trophic Role for Leukocyte-Derived PGE(2)

Authors:
Feng Y, Renshaw S, Martin P
Citation:
Curr Biol. 2012 Jul 10;22(13):1253-9. Epub 2012 May 31
Epub:
Not Epub
Abstract:
Epidemiology studies and clinical trials have suggested that the use of non-steroidal anti-inflammatory drugs (NSAIDs),...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Feng Y, Renshaw S, Martin P. Live Imaging of Tumor Initiation in Zebrafish Larvae Reveals a Trophic Role for Leukocyte-Derived PGE(2). Curr Biol. 2012 Jul 10;22(13):1253-9. Epub 2012 May 31.

Local In Vivo GSK3β Knockdown Promotes Pancreatic β Cell and Acinar Cell Regeneration in 90% Pancreatectomized Rat

Authors:
Figeac F, Ilias A, Bailbe D, Portha B, Movassat J
Citation:
Mol Ther. 2012;[Epub ahead of print] doi:10.1038/mt.2012.112
Epub:
Not Epub
Abstract:
Endocrine and exocrine insufficiencies are associated with serious diseases such as diabetes and pancreatitis, respectively....
Organism or Cell Type:
Rat
Citation Extract:
Figeac F, Ilias A, Bailbe D, Portha B, Movassat J. Local In Vivo GSK3β Knockdown Promotes Pancreatic β Cell and Acinar Cell Regeneration in 90% Pancreatectomized Rat. Mol Ther. 2012;[Epub ahead of print] doi:10.1038/mt.2012.112.

MicroRNAs are essential for development and function of inner ear hair cells in vertebrates

Authors:
Friedman LM, Dror AA, Mor E, Tenne T, Toren G, Satoh T, Biesemeier DJ, Shomron N, Fekete DM, Hornstein E, Avraham KB
Citation:
Proc Natl Acad Sci U S A. 2009 Apr 28. [Epub ahead of print]
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) inhibit the translation of target mRNAs and affect, directly or indirectly, the expression of a large...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Friedman LM, Dror AA, Mor E, Tenne T, Toren G, Satoh T, Biesemeier DJ, Shomron N, Fekete DM, Hornstein E, Avraham KB. MicroRNAs are essential for development and function of inner ear hair cells in vertebrates. Proc Natl Acad Sci U S A. 2009 Apr 28. [Epub ahead of print] .

miR-126 regulates angiogenic signaling and vascular integrity

Authors:
Fish JE, Santoro MM, Morton SU, Yu S, Yeh RF, Wythe JD, Ivey KN, Bruneau BG, Stainier DY, Srivastava D
Citation:
Dev Cell. 2008 Aug;15(2):272-84
Epub:
Not Epub
Abstract:
Precise regulation of the formation, maintenance, and remodeling of the vasculature is required for normal development, tissue...
Organism or Cell Type:
zebrafish
Citation Extract:
Fish JE, Santoro MM, Morton SU, Yu S, Yeh RF, Wythe JD, Ivey KN, Bruneau BG, Stainier DY, Srivastava D. miR-126 regulates angiogenic signaling and vascular integrity. Dev Cell. 2008 Aug;15(2):272-84.

miR-8 microRNAs regulate the response to osmotic stress in zebrafish embryos

Authors:
Flynt AS, Thatcher EJ, Burkewitz K, Li N, Liu Y, Patton JG
Citation:
J Cell Biol. 2009 Mar 30. [Epub ahead of print]
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are highly conserved small RNAs that act as translational regulators of gene expression, exerting their...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Flynt AS, Thatcher EJ, Burkewitz K, Li N, Liu Y, Patton JG. miR-8 microRNAs regulate the response to osmotic stress in zebrafish embryos. J Cell Biol. 2009 Mar 30. [Epub ahead of print].

Mismatched single stranded antisense oligonucleotides can induce efficient dystrophin splice switching

Authors:
Fragall CT, Adams AM, Johnsen RD, Kole R, Fletcher S, Wilton SD
Citation:
BMC Med Genet. 2011 Oct 20;12(1):141. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Antisense oligomer induced exon skipping aims to reduce the severity of Duchenne muscular dystrophy by redirecting...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: human myoblasts from fibroblasts
Citation Extract:
Fragall CT, Adams AM, Johnsen RD, Kole R, Fletcher S, Wilton SD. Mismatched single stranded antisense oligonucleotides can induce efficient dystrophin splice switching. BMC Med Genet. 2011 Oct 20;12(1):141. [Epub ahead of print].

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