Successful Knockdown of Aquaporin 1 (AQP1) Protein Expression in American Eel (Anguilla rostrata) Gastrointestinal Tract Using Direct-Infusions of Vivo-Morpholinos

Vivo-morpholinos are artificial nucleic acids that can block the protein production from a particular gene. Direct intestinal infusions of vivo-morpholinos were used to ‘knockdown’ (reduce) the amount of aquaporin 1 water channel protein to be able to see differences in function with or without the protein.