Citation:
Dev Cell. 2015;32(1)7-8. doi:10.1016/j.devcel.2014.12.012
Abstract:
The morpholino anti-sense technology has been used extensively to test gene function. The zebrafish model allows a detailed comparison of knockdown (anti-sense) and knockout (mutation) effects. Recent studies reveal that these two approaches can often lead to surprisingly different phenotypes, thus raising a number of important questions.
Epub:
Not Epub
Link to Publication:
http://www.cell.com/developmental-cell/abstract/S1534-5807%2814%2900833-8