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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Drug screening in a zebrafish model of Duchenne muscular dystrophy
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Citation:
Proc Natl Acad Sci U S A. 2011 Mar 29;108(13):5331-6. Epub 2011 Mar 14 Epub:
Not Epub Abstract:
Two known zebrafish dystrophin mutants, sapje and sapje-like (sap(c/100)), represent excellent small-animal models of human... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Kawahara G, Karpf JA, Myers JA, Alexander MS, Guyon JR, Kunkel LM. Drug screening in a zebrafish model of Duchenne muscular dystrophy. Proc Natl Acad Sci U S A. 2011 Mar 29;108(13):5331-6. Epub 2011 Mar 14. |
Dynamic glucoregulation and mammalian-like responses to metabolic and developmental disruption in zebrafish
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Citation:
Gen Comp Endocrinol. 2011 January 15; 170(2): 334–345. Epub:
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Zebrafish embryos are emerging as models of glucose metabolism. However, patterns of endogenous glucose levels, and the role of... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Jurczyk A, Roy N, Bajwa R, Gut P, Lipson K, Yang C, Covassin L, Racki WJ, Rossini AA, Phillips N, Stainier DY, Greiner DL, Brehm MA, Bortell R, Diiorio P. Dynamic glucoregulation and mammalian-like responses to metabolic and developmental disruption in zebrafish. Gen Comp Endocrinol. 2011 January 15; 170(2): 334–345. . |
Evolutionarily conserved gene family important for fat storage
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Citation:
Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):94-9. Epub 2007 Dec 26 Epub:
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The ability to store fat in the form of cytoplasmic triglyceride droplets is conserved from Saccharomyces cerevisiae to humans... Delivery Method:
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zebrafish Citation Extract: Kadereit B, Kumar P, Wang WJ, Miranda D, Snapp EL, Severina N, Torregroza I, Evans T, Silver DL. Evolutionarily conserved gene family important for fat storage. Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):94-9. Epub 2007 Dec 26. |
Expression of ROCK-1 in Human Pancreatic Cancer: Its Down-Regulation by Morpholino Oligo Antisense Can Reduce the Migration of Pancreatic Cancer Cells In Vitro
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Citation:
Pancreas. 2002 Apr;24(3):251-7 Epub:
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INTRODUCTION: Invasion and metastasis of cancer cells require cell motility and adhesion. The small GTPase Rho and one of its... Delivery Method:
culture: Incubation & free uptake Organism or Cell Type:
Cell Culture: human pancreatic cell: MIA PaCa-2, and Panc-1 Citation Extract: Kaneko K, Satoh K, Masamune A, Satoh A, Shimosegawa T. Expression of ROCK-1 in Human Pancreatic Cancer: Its Down-Regulation by Morpholino Oligo Antisense Can Reduce the Migration of Pancreatic Cancer Cells In Vitro. Pancreas. 2002 Apr;24(3):251-7. |
Fgf signaling controls pharyngeal taste bud formation through miR-200 and Delta-Notch activity
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Citation:
Development. 2011;138:3473-84. doi:10.1242/dev.058669 Epub:
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Taste buds, the taste sensory organs, are conserved in vertebrates and composed of distinct cell types, including taste... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Kapsimali M, Kaushik A-L, Gibon G, Dirian L, Ernest S, Rosa FM. Fgf signaling controls pharyngeal taste bud formation through miR-200 and Delta-Notch activity. Development. 2011;138:3473-84. doi:10.1242/dev.058669. |
FUS and TARDBP but Not SOD1 Interact in Genetic Models of Amyotrophic Lateral Sclerosis
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PLoS Genet. 2011;7(8): e1002214 Epub:
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Mutations in the SOD1 and TARDBP genes have been commonly identified in Amyotrophic Lateral Sclerosis (ALS). Recently,... Delivery Method:
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zebrafish Citation Extract: Kabashi E, Bercier V, Lissouba A, Liao M, Brustein E, Rouleau GA, Drapeau P. FUS and TARDBP but Not SOD1 Interact in Genetic Models of Amyotrophic Lateral Sclerosis. PLoS Genet. 2011;7(8): e1002214. |
Gadd45a and Gadd45g regulate neural development and exit from pluripotency in Xenopus
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Citation:
Mech Dev. 2011 Sep-Dec;128(7-10):401-11. doi: 10.1016/j.mod.2011.08.002. Epub 2011 Aug 10. Epub:
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Gadd45 genes encode a small family of multifunctional stress response proteins, mediating cell proliferation, apoptosis, DNA... Organism or Cell Type:
Xenopus Citation Extract: Kaufmann LT, Niehrs C. Gadd45a and Gadd45g regulate neural development and exit from pluripotency in Xenopus. Mech Dev. 2011 Sep-Dec;128(7-10):401-11. doi: 10.1016/j.mod.2011.08.002. Epub 2011 Aug 10.. |
Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo
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Citation:
Hum Mol Genet. 2010 Feb 15;19(4):671-83. Epub 2009 Dec 3. Erratum in: Hum Mol Genet. 2010 Aug 1;19(15):3102 Epub:
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TDP-43 has been found in inclusion bodies of multiple neurological disorders, including amyotrophic lateral sclerosis,... Delivery Method:
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zebrafish Citation Extract: Kabashi E, Lin L, Tradewell ML, Dion PA, Bercier V, Bourgouin P, Rochefort D, Bel Hadj S, Durham HD, Vande Velde C, Rouleau GA, Drapeau P. Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo. Hum Mol Genet. 2010 Feb 15;19(4):671-83. Epub 2009 Dec 3. Erratum in: Hum Mol Genet. 2010 Aug 1;19(15):3102. |
Gelsolin is a dorsalizing factor in zebrafish
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Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3287-92 Epub:
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The gene for gelsolin (an actin-binding, cytoskeletal regulatory protein) was shown earlier to be specialized for high corneal... Delivery Method:
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zebrafish Citation Extract: Kanungo J, Kozmik Z, Swamynathan SK, Piatigorsky J. Gelsolin is a dorsalizing factor in zebrafish. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3287-92. |
Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development
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Citation:
Development 2003 Apr 15;130(8):1549-1564 Epub:
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Gli proteins regulate the transcription of Hedgehog (Hh) target genes. Genetic studies in mouse have shown that Gli1 is not... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Karlstrom RO, Tyurina OV, Kawakami A, Nishioka N, Talbot WS, Sasaki H, Schier AF. Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. Development 2003 Apr 15;130(8):1549-1564. |