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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Inhibition of Respiratory Syncytial Virus Infections With Morpholino Oligomers in Cell Cultures and in Mice

Authors:
Lai SH, Stein DA, Guerrero-Plata A, Liao SL, Ivanciuc T, Hong C, Iversen PL, Casola A, Garofalo RP
Citation:
Mol Ther. 2008 Apr 29; [Epub ahead of print]
Epub:
Not Epub
Abstract:
Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infection in infants, young children, and high-...
Delivery Method:
Peptide-coupled intranasal
Organism or Cell Type:
mice and cell culture
Citation Extract:
Lai SH, Stein DA, Guerrero-Plata A, Liao SL, Ivanciuc T, Hong C, Iversen PL, Casola A, Garofalo RP. Inhibition of Respiratory Syncytial Virus Infections With Morpholino Oligomers in Cell Cultures and in Mice. Mol Ther. 2008 Apr 29; [Epub ahead of print] .

Involvement of calcitonin and its receptor in the control of calcium regulating-genes and calcium homeostasis in zebrafish (Danio rerio)

Authors:
Lafont AG, Wang YF, Chen GD, Liao BK, Tseng YC, Huang CJ, Hwang PP
Citation:
J Bone Miner Res. 2010 Nov 23. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Calcitonin (CT) is one of the hormones involved in the vertebrate calcium regulation. It was proposed to act as a hypocalcemic...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lafont AG, Wang YF, Chen GD, Liao BK, Tseng YC, Huang CJ, Hwang PP. Involvement of calcitonin and its receptor in the control of calcium regulating-genes and calcium homeostasis in zebrafish (Danio rerio). J Bone Miner Res. 2010 Nov 23. [Epub ahead of print].

Loss of Lrp2 in zebrafish disrupts pronephric tubular clearance but not forebrain development

Authors:
Kur E, Christa A, Veth KN, Gajera CR, Andrade-Navarro MA, Zhang J, Willer JR, Gregg RG, Abdelilah-Seyfried S, Bachmann S, Link BA, Hammes A, Willnow TE
Citation:
Dev Dyn. 2011 Jun;240(6):1567-77. doi: 10.1002/dvdy.22624. Epub 2011 Mar 31.
Epub:
Not Epub
Abstract:
Low-density lipoprotein receptor-related protein 2 (LRP2) is a multifunctional cell surface receptor conserved from nematodes...
Organism or Cell Type:
zebrafish
Citation Extract:
Kur E, Christa A, Veth KN, Gajera CR, Andrade-Navarro MA, Zhang J, Willer JR, Gregg RG, Abdelilah-Seyfried S, Bachmann S, Link BA, Hammes A, Willnow TE. Loss of Lrp2 in zebrafish disrupts pronephric tubular clearance but not forebrain development. Dev Dyn. 2011 Jun;240(6):1567-77. doi: 10.1002/dvdy.22624. Epub 2011 Mar 31..

MCTP2 is a dosage sensitive gene required for cardiac outflow tract development

Authors:
Lalani SR, Ware SM, Wang X, Zapata G, Tian Q, Franco L, Jiang Z, Bucasas K, Scott DA, Campeau PM, Hanchard N, Umaña L, Cast A, Patel A, Cheung SW, McBride KL, Bray M, Chinault AC, Boggs BA, Huang M, Baker MR, Hamilton S, Towbin J, Jefferies JL, Fernbach SD, Potocki L, Belmont JW
Citation:
Hum Mol Genet. 2013 Jun 16. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Coarctation of the aorta (CoA) and hypoplastic left heart syndrome (HLHS) have been reported in rare individuals with large...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Lalani SR, Ware SM, Wang X, Zapata G, Tian Q, Franco L, Jiang Z, Bucasas K, Scott DA, Campeau PM, Hanchard N, Umaña L, Cast A, Patel A, Cheung SW, McBride KL, Bray M, Chinault AC, Boggs BA, Huang M, Baker MR, Hamilton S, Towbin J, Jefferies JL, Fernbach SD, Potocki L, Belmont JW. MCTP2 is a dosage sensitive gene required for cardiac outflow tract development. Hum Mol Genet. 2013 Jun 16. [Epub ahead of print].

Mesendodermal signals required for otic induction: Bmp-antagonists cooperate with Fgf and can facilitate formation of ectopic otic tissue

Authors:
Kwon HJ, Riley BB
Citation:
Dev Dyn. 2009 May 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Induction of otic placodes requires Fgf from surrounding tissues. We tested the hypothesis that mesendodermally derived Bmp-...
Organism or Cell Type:
zebrafish
Citation Extract:
Kwon HJ, Riley BB. Mesendodermal signals required for otic induction: Bmp-antagonists cooperate with Fgf and can facilitate formation of ectopic otic tissue. Dev Dyn. 2009 May 4. [Epub ahead of print].

MicroRNA-23 Restricts Cardiac Valve Formation by Inhibiting Has2 and Extracellular Hyaluronic Acid Production

Authors:
Lagendijk AK, Goumans MJ, Burkhard SB, Bakkers J
Citation:
Circ Res. 2011 Sep 2;109(6):649-57. Epub 2011 Jul 21
Epub:
Not Epub
Abstract:
Rationale: Since their discovery almost 20 years ago, microRNAs have been shown to perform essential roles during tissue...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lagendijk AK, Goumans MJ, Burkhard SB, Bakkers J. MicroRNA-23 Restricts Cardiac Valve Formation by Inhibiting Has2 and Extracellular Hyaluronic Acid Production. Circ Res. 2011 Sep 2;109(6):649-57. Epub 2011 Jul 21.

Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm induction

Authors:
Kunwar PS, Zimmerman S, Bennett JT, Chen Y, Whitman M, Schier AF
Citation:
Development. 2003 Dec;130(23):5589-99. Epub 2003 Oct 1
Epub:
Not Epub
Abstract:
Transcription factors belonging to the FoxH1 and Mixer families are required for facets of Nodal signaling during vertebrate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kunwar PS, Zimmerman S, Bennett JT, Chen Y, Whitman M, Schier AF. Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm induction. Development. 2003 Dec;130(23):5589-99. Epub 2003 Oct 1.

Molecular target validation, antimicrobial delivery, and potential treatment of Toxoplasma gondii infections

Authors:
Lai BS, Witola WH, El Bissati KE, Zhou Y, Mui E, Fomovska A, McLeod R
Citation:
PNAS. 2012;[Epub ahead of print] doi:10.1073/pnas.1208775109
Epub:
Not Epub
Abstract:
Toxoplasma gondii persistently infects over two billion people worldwide. It can cause substantial morbidity and mortality....
Delivery Method:
peptide-coupled and Vivo-Morpholino
Organism or Cell Type:
Toxoplasma gondii
Citation Extract:
Lai BS, Witola WH, El Bissati KE, Zhou Y, Mui E, Fomovska A, McLeod R. Molecular target validation, antimicrobial delivery, and potential treatment of Toxoplasma gondii infections. PNAS. 2012;[Epub ahead of print] doi:10.1073/pnas.1208775109.

Netrin-4 acts as a pro-angiogenic factor during zebrafish development

Authors:
Lambert E, Coissieux MM, Laudet V, Mehlen P
Citation:
J Biol Chem. 2011 Dec 16. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Netrins form an heterogeneous family of laminin related molecules with multifunctional activities. Netrin-4, the most distant...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lambert E, Coissieux MM, Laudet V, Mehlen P. Netrin-4 acts as a pro-angiogenic factor during zebrafish development. J Biol Chem. 2011 Dec 16. [Epub ahead of print].

Netrin/DCC Signaling Guides Olfactory Sensory Axons to Their Correct Location in the Olfactory Bulb

Authors:
Lakhina V, Marcaccio CL, Shao X, Lush ME, Jain RA, Fujimoto E, Bonkowsky JL, Granato M, Raper JA
Citation:
J Neurosci. 2012;32(13):4440-4456. doi:10.1523/JNEUROSCI.4442-11.2012
Epub:
Not Epub
Abstract:
Olfactory sensory neurons expressing particular olfactory receptors project to specific reproducible locations within the bulb...
Organism or Cell Type:
zebrafish
Citation Extract:
Lakhina V, Marcaccio CL, Shao X, Lush ME, Jain RA, Fujimoto E, Bonkowsky JL, Granato M, Raper JA. Netrin/DCC Signaling Guides Olfactory Sensory Axons to Their Correct Location in the Olfactory Bulb. J Neurosci. 2012;32(13):4440-4456. doi:10.1523/JNEUROSCI.4442-11.2012 .

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