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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain

Authors:
Le Bras B, Barallobre MJ, Homman-Ludiye J, Ny A, Wyns S, Tammela T, Haiko P, Karkkainen MJ, Yuan L, Muriel MP, Chatzopoulou E, Breant C, Zalc B, Carmeliet P, Alitalo K, Eichmann A, Thomas JL
Citation:
Nat Neurosci. 2006 Mar;9(3):340-348. Epub 2006 Feb 5
Epub:
Not Epub
Abstract:
Vascular endothelial growth factor C (VEGF-C) was first identified as a regulator of the vascular system, where it is required...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Le Bras B, Barallobre MJ, Homman-Ludiye J, Ny A, Wyns S, Tammela T, Haiko P, Karkkainen MJ, Yuan L, Muriel MP, Chatzopoulou E, Breant C, Zalc B, Carmeliet P, Alitalo K, Eichmann A, Thomas JL. VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain. Nat Neurosci. 2006 Mar;9(3):340-348. Epub 2006 Feb 5.

Xenopus Cyr61 regulates gastrulation movements and modulates Wnt signalling

Authors:
Latinkic BV, Mercurio S, Bennett B, Hirst EM, Xu Q, Lau LF, Mohun TJ, Smith JC
Citation:
Development. 2003 Jun;130(11):2429-41
Epub:
Not Epub
Abstract:
Cyr61 is a secreted, heparin-binding, extracellular matrix-associated protein whose activities include the promotion of...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Latinkic BV, Mercurio S, Bennett B, Hirst EM, Xu Q, Lau LF, Mohun TJ, Smith JC. Xenopus Cyr61 regulates gastrulation movements and modulates Wnt signalling. Development. 2003 Jun;130(11):2429-41.

Zebrafish as a Model Organism for the Identification and Characterization of Drugs and Genes Affecting p53 Signaling

Authors:
Langheinrich U, Hennen E, Stott G, Vacun G
Citation:
Curr Biol. 2002 Dec 10;12(23):2023-8
Epub:
Not Epub
Abstract:
p53 and its main negative regulator, Mdm2, are key players in mammalian cancer development. Activation of the transcription...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Langheinrich U, Hennen E, Stott G, Vacun G. Zebrafish as a Model Organism for the Identification and Characterization of Drugs and Genes Affecting p53 Signaling. Curr Biol. 2002 Dec 10;12(23):2023-8.

Zebrafish embryos express an orthologue of HERG and are sensitive toward a range of QT-prolonging drugs inducing severe arrhythmia.

Authors:
Langheinrich U, Vacun G, Wagner T
Citation:
Toxicol Appl Pharmacol. 2003 Dec 15;193(3):370-82
Epub:
Not Epub
Abstract:
A wide range of drugs has been shown to prolong the QT interval of the electrocardiogram by blocking the pore-forming subunit...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Langheinrich U, Vacun G, Wagner T. Zebrafish embryos express an orthologue of HERG and are sensitive toward a range of QT-prolonging drugs inducing severe arrhythmia.. Toxicol Appl Pharmacol. 2003 Dec 15;193(3):370-82.

ZFPIP/Zfp462 is maternally required for proper early Xenopus laevis development

Authors:
Laurent A, Masse J, Omilli F, Deschamps S, Richard-Parpaillon L, Chartrain I, Pellerin I
Citation:
Dev Biol. 2008 Dec 16. [Epub ahead of print]
Epub:
Not Epub
Abstract:
ZFPIP (Zinc Finger Pbx1 Interacting Protein) has been recently identified in our laboratory in a yeast two hybrid screen using...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Laurent A, Masse J, Omilli F, Deschamps S, Richard-Parpaillon L, Chartrain I, Pellerin I. ZFPIP/Zfp462 is maternally required for proper early Xenopus laevis development. Dev Biol. 2008 Dec 16. [Epub ahead of print].

Protocadherin-18a has a role in cell adhesion, behavior and migration in zebrafish development

Authors:
Aamar E, Dawid IB
Citation:
Dev Biol. 2008 Jun 15;318(2):335-46. Epub 2008 Apr 9.
Epub:
Not Epub
Abstract:
Protocadherin-18a (Pcdh18a) belongs to the delta2-protocadherins, which constitute the largest subgroup within the cadherin...
Organism or Cell Type:
zebrafish
Citation Extract:
Aamar E, Dawid IB. Protocadherin-18a has a role in cell adhesion, behavior and migration in zebrafish development. Dev Biol. 2008 Jun 15;318(2):335-46. Epub 2008 Apr 9..

A histone H3 lysine 27 demethylase regulates animal posterior development

Authors:
Lan F, Bayliss PE, Rinn JL, Whetstine JR, Wang JK, Chen S, Iwase S, Alpatov R, Issaeva I, Canaani E, Roberts TM, Chang HY, Shi Y
Citation:
Nature. 2007 Oct 11;449(7163):689-94. Epub 2007 Sep 12.
Epub:
Not Epub
Abstract:
The recent discovery of a large number of histone demethylases suggests a central role for these enzymes in regulating histone...
Organism or Cell Type:
zebrafish
Citation Extract:
Lan F, Bayliss PE, Rinn JL, Whetstine JR, Wang JK, Chen S, Iwase S, Alpatov R, Issaeva I, Canaani E, Roberts TM, Chang HY, Shi Y. A histone H3 lysine 27 demethylase regulates animal posterior development. Nature. 2007 Oct 11;449(7163):689-94. Epub 2007 Sep 12..

A microtubule-binding Rho-GEF controls cell morphology during convergent extension of Xenopus laevis

Authors:
Kwan KM, Kirschner MW
Citation:
Development. 2005 Oct;132(20):4599-610. Epub 2005 Sep 21
Epub:
Not Epub
Abstract:
During Xenopus development, convergent extension movements mediated by cell intercalation drive axial elongation. While many...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kwan KM, Kirschner MW. A microtubule-binding Rho-GEF controls cell morphology during convergent extension of Xenopus laevis. Development. 2005 Oct;132(20):4599-610. Epub 2005 Sep 21.

A new molecular logic for BMP-mediated dorsoventral patterning in the leech Helobdella

Authors:
Kuo DH, Weisblat DA
Citation:
Curr Biol. 2011 Aug 9;21(15):1282-8. Epub 2011 Jul 21
Epub:
Not Epub
Abstract:
Bone morphogenetic protein (BMP) signaling is broadly implicated in dorsoventral (DV) patterning of bilaterally symmetric...
Delivery Method:
Microinjection
Organism or Cell Type:
Helobdella (leech)
Citation Extract:
Kuo DH, Weisblat DA. A new molecular logic for BMP-mediated dorsoventral patterning in the leech Helobdella. Curr Biol. 2011 Aug 9;21(15):1282-8. Epub 2011 Jul 21.

A novel intellectual disability syndrome caused by GPI anchor deficiency due to homozygous mutations in PIGT

Authors:
Kvarnung M, Nilsson D, Lindstrand A, Korenke GC, Chiang SCC, Blennow E, Bergmann M, Stödberg T, Mäkitie O, Anderlid B-M, Bryceson YT, Nordenskjöld M, Nordgren A
Citation:
J Med Genet. 2013;[Epub ahead of print] doi:10.1136/jmedgenet-2013-101654
Epub:
Not Epub
Abstract:
Purpose To delineate the molecular basis for a novel autosomal recessive syndrome, characterised by distinct facial features...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kvarnung M, Nilsson D, Lindstrand A, Korenke GC, Chiang SCC, Blennow E, Bergmann M, Stödberg T, Mäkitie O, Anderlid B-M, Bryceson YT, Nordenskjöld M, Nordgren A. A novel intellectual disability syndrome caused by GPI anchor deficiency due to homozygous mutations in PIGT. J Med Genet. 2013;[Epub ahead of print] doi:10.1136/jmedgenet-2013-101654.

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