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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
A Novel Anti-Tumor Inhibitor Identified by Virtual Screen with PLK1 Structure and Zebrafish Assay
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Citation:
PLoS ONE. 2013;8(4):e53317. doi:10.1371/journal.pone.0053317 Epub:
Not Epub Abstract:
Polo-like kinase 1 (PLK1), one of the key regulators of mitosis, is a target for cancer therapy due to its abnormally high... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Lu J, Xin S, Meng H, Veldman M, Schoenfeld D, Che C, Yan R, Zhong H, Li S, Lin S. A Novel Anti-Tumor Inhibitor Identified by Virtual Screen with PLK1 Structure and Zebrafish Assay. PLoS ONE. 2013;8(4):e53317. doi:10.1371/journal.pone.0053317. |
A novel antisense inhibitor of MMP-9 attenuates angiogenesis, human prostate cancer cell invasion and tumorigenicity
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Citation:
Cancer Gene Ther. 2003 Nov;10(11):823-32 Epub:
Not Epub Abstract:
Androgen deprivation therapy causes a paradoxical elevation of matrix metalloproteinases (MMPs) including MMP-9 resulting in... Delivery Method:
culture: scrape loading and syringe loading; mouse: IP injection Organism or Cell Type:
in vitro: cell culture: HeLa and DU 145 cell ; in vivo: mice nude Citation Extract: London CA, Sekhon HS, Arora V, Stein DA, Iversen PL, Devi GR. A novel antisense inhibitor of MMP-9 attenuates angiogenesis, human prostate cancer cell invasion and tumorigenicity. Cancer Gene Ther. 2003 Nov;10(11):823-32. |
A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development
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Citation:
Genes Dev. 2007 Apr 1;21(7):784-96. Epub 2007 Mar 20 Epub:
Not Epub Abstract:
Mitochondria play a central role in the regulation of programmed cell death signaling. Here, we report the finding of a... Organism or Cell Type:
zebrafish Citation Extract: Lu G, Ren S, Korge P, Choi J, Dong Y, Weiss J, Koehler C, Chen JN, Wang Y. A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development. Genes Dev. 2007 Apr 1;21(7):784-96. Epub 2007 Mar 20. |
A TGF-beta control element required for SM alpha -actin expression in vivo also partially mediates GKLF-dependent transcriptional repression.
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Citation:
J Biol Chem. 2003 Nov 28; 278(48): 48004-11. Epub 2003 Sep 10. Epub:
Not Epub Abstract:
We previously demonstrated that a conserved TGF-beta control element (TCE) within the 5 region of the smooth muscle cell (SMC)... Delivery Method:
Special Delivery Organism or Cell Type:
cell culture: rat aortic smooth muscle cells Citation Extract: Liu Y, Sinha S, Owens GK.. A TGF-beta control element required for SM alpha -actin expression in vivo also partially mediates GKLF-dependent transcriptional repression.. J Biol Chem. 2003 Nov 28; 278(48): 48004-11. Epub 2003 Sep 10.. |
A Unique Feature of Toll/IL-1 Receptor Domain-Containing Adaptor Protein Is Partially Responsible for Lipopolysaccharide Insensitivity in Zebrafish with a Highly Conserved Function of Myd88
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Citation:
J Immunol. 2010 Aug 11. [Epub ahead of print] Epub:
Not Epub Abstract:
MyD88 and Toll/IL-1R domain-containing adaptor protein (TIRAP) are required for the TLR4 response to LPS stimulation in mammals... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu Y, Li M, Fan S, Lin Y, Lin B, Luo F, Zhang C, Chen S, Li Y, Xu A. A Unique Feature of Toll/IL-1 Receptor Domain-Containing Adaptor Protein Is Partially Responsible for Lipopolysaccharide Insensitivity in Zebrafish with a Highly Conserved Function of Myd88. J Immunol. 2010 Aug 11. [Epub ahead of print]. |
A zebrafish model of intrahepatic cholangiocarcinoma by dual expression of hepatitis B virus X and hepatitis C virus core protein in liver
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Citation:
Hepatology. 2012 Dec;56(6):2268-76. doi: 10.1002/hep.25914. PMID: 22729936 Epub:
Not Epub Abstract:
The mechanisms that mediate the initiation and development of intrahepatic cholangiocarcinoma (ICC) associated with hepatitis B... Organism or Cell Type:
zebrafish Citation Extract: Liu W, Chen JR, Hsu CH, Li YH, Chen YM, Lin CY, Huang SJ, Chang ZK, Chen YC, Lin CH, Gong HY, Lin CC, Kawakami K, Wu JL. A zebrafish model of intrahepatic cholangiocarcinoma by dual expression of hepatitis B virus X and hepatitis C virus core protein in liver. Hepatology. 2012 Dec;56(6):2268-76. doi: 10.1002/hep.25914. PMID: 22729936. |
Amino acid variations resulting in functional and nonfunctional zebrafish P2X(1) and P2X (5.1) receptors
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Citation:
Purinergic Signal. 2008 Dec;4(4):383-92. Epub 2008 Oct 11 Epub:
Not Epub Abstract:
Several zebrafish P2X receptors (zP2X(1), zP2X(2), and zP2X(5.1)) have been reported to produce little or no current although... Organism or Cell Type:
zebrafish Citation Extract: Low SE, Kuwada JY, Hume RI. Amino acid variations resulting in functional and nonfunctional zebrafish P2X(1) and P2X (5.1) receptors. Purinergic Signal. 2008 Dec;4(4):383-92. Epub 2008 Oct 11. |
Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration
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Citation:
Nat Cell Biol. 2013;[Epub ahead of print] doi:/10.1038/ncb2659 Epub:
Not Epub Abstract:
Understanding the molecular mechanisms that promote successful tissue regeneration is critical for continued advancements in... Organism or Cell Type:
Xenopus Citation Extract: Love NR, Chen Y, Ishibashi S, Kritsiligkou P, Lea R, Koh Y, Gallop JL, Dorey K, Amaya E. Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration. Nat Cell Biol. 2013;[Epub ahead of print] doi:/10.1038/ncb2659. |
An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin
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Citation:
Nat Neurosci.2012 May;15(5):713-21. Epub:
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The Huntington's disease gene product, huntingtin, is indispensable for neural tube formation, but its role is obscure. We... Organism or Cell Type:
zebrafish Citation Extract: Lo Sardo V, Zuccato C, Gaudenzi G, Vitali B, Ramos C, Tartari M, Myre MA, Walker JA, Pistocchi A, Conti L, Valenza M, Drung B, Schmidt B, Gusella J, Zeitlin S, Cotelli F, Cattaneo E. An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin. Nat Neurosci.2012 May;15(5):713-21.. |
Araf kinase antagonizes Nodal-Smad2 activity in mesendoderm development by directly phosphorylating the Smad2 linker region
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Citation:
Nat Commun. 2013;[Epub ahead of print] doi:10.1038/ncomms2762 Epub:
Not Epub Abstract:
Smad2/3-mediated transforming growth factor β signalling and the Ras-Raf-Mek-Erk cascade have important roles in stem cell and... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu X, Xiong C, Jia S, Zhang Y, Chen Y-G, Wang Q, Meng A. Araf kinase antagonizes Nodal-Smad2 activity in mesendoderm development by directly phosphorylating the Smad2 linker region. Nat Commun. 2013;[Epub ahead of print] doi:10.1038/ncomms2762. |