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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Repair of a Splicing Defect in Erythroid Cells from Patients with beta-Thalassemia/HbE Disorder

Authors:
Suwanmanee T, Sierakowska H, Fucharoen S, Kole R
Citation:
Mol Ther. 2002 Dec;6(6):718-26.
Epub:
Not Epub
Abstract:
A HeLa cell line stably expressing the human beta-globin gene carrying thalassemic mutations beta(E)/IVS1-6 served as a...
Delivery Method:
scrape loading and syringe loading
Organism or Cell Type:
cell culture: C2C12 cells
Citation Extract:
Suwanmanee T, Sierakowska H, Fucharoen S, Kole R. Repair of a Splicing Defect in Erythroid Cells from Patients with beta-Thalassemia/HbE Disorder. Mol Ther. 2002 Dec;6(6):718-26..

Restoration of Human beta-Globin Gene Expression in Murine and Human IVS2-654 Thalassemic Erythroid Cells by Free Uptake of Antisense Oligonucleotides

Authors:
Suwanmanee T, Sierakowska H, Lacerra G, Svasti S, Kirby S, Walsh CE, Fucharoen S, Kole R
Citation:
Mol Pharmacol. 2002 Sep;62(3):545-53.
Epub:
Not Epub
Abstract:
Correct human beta-globin mRNA has been restored in erythroid cells from transgenic mice carrying the human gene with beta-...
Delivery Method:
syringe loading and free uptake
Organism or Cell Type:
cell culture: Hela and human erythroid precursor cells
Citation Extract:
Suwanmanee T, Sierakowska H, Lacerra G, Svasti S, Kirby S, Walsh CE, Fucharoen S, Kole R. Restoration of Human beta-Globin Gene Expression in Murine and Human IVS2-654 Thalassemic Erythroid Cells by Free Uptake of Antisense Oligonucleotides. Mol Pharmacol. 2002 Sep;62(3):545-53..

Retinoids signal directly to zebrafish endoderm to specify insulin-expressing beta-cells

Authors:
Stafford D, White RJ, Kinkel MD, Linville A, Schilling TF, Prince VE
Citation:
Development. 2006 Mar;133(5):949-56. Epub 2006 Feb 1
Epub:
Not Epub
Abstract:
During vertebrate development, the endodermal germ layer becomes regionalized along its anteroposterior axis to give rise to a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stafford D, White RJ, Kinkel MD, Linville A, Schilling TF, Prince VE. Retinoids signal directly to zebrafish endoderm to specify insulin-expressing beta-cells. Development. 2006 Mar;133(5):949-56. Epub 2006 Feb 1.

Retinol dehydrogenase 10 is a feedback regulator of retinoic acid signalling during axis formation and patterning of the central nervous system

Authors:
Strate I, Min TH, Iliev D, Pera EM
Citation:
Development. 2009 Feb;136(3):461-72
Epub:
Not Epub
Abstract:
Retinoic acid (RA) is an important morphogen that regulates many biological processes, including the development of the central...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Strate I, Min TH, Iliev D, Pera EM. Retinol dehydrogenase 10 is a feedback regulator of retinoic acid signalling during axis formation and patterning of the central nervous system. Development. 2009 Feb;136(3):461-72.

RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice

Authors:
Svasti S, Suwanmanee T, Fucharoen S, Moulton HM, Nelson MH, Maeda N, Smithies O, Kole R
Citation:
Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1205-10. Epub 2009 Jan 21
Epub:
Not Epub
Abstract:
Repair of beta-globin pre-mRNA rendered defective by a thalassemia-causing splicing mutation, IVS2-654, in intron 2 of the...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mouse: IVS2-654
Citation Extract:
Svasti S, Suwanmanee T, Fucharoen S, Moulton HM, Nelson MH, Maeda N, Smithies O, Kole R. RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice. Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1205-10. Epub 2009 Jan 21.

Sdf1a patterns zebrafish melanophores and links the somite and melanophore pattern defects in choker mutants

Authors:
Svetic V, Hollway GE, Elworthy S, Chipperfield TR, Davison C, Adams RJ, Eisen JS, Ingham PW, Currie PD, Kelsh RN
Citation:
Development. 2007 Mar;134(5):1011-22. Epub 2007 Jan 31.
Epub:
Not Epub
Abstract:
Pigment pattern formation in zebrafish presents a tractable model system for studying the morphogenesis of neural crest...
Organism or Cell Type:
zebrafish
Citation Extract:
Svetic V, Hollway GE, Elworthy S, Chipperfield TR, Davison C, Adams RJ, Eisen JS, Ingham PW, Currie PD, Kelsh RN. Sdf1a patterns zebrafish melanophores and links the somite and melanophore pattern defects in choker mutants. Development. 2007 Mar;134(5):1011-22. Epub 2007 Jan 31..

Sfrp5 Modulates Both Wnt and BMP Signaling and Regulates Gastrointestinal Organogensis in the Zebrafish, Danio rerio

Authors:
Stuckenholz C, Lu L, Thakur PC, Choi T-Y, Shin D, Bahary N
Citation:
PLoS ONE. 2013;8(4):e62470. doi:10.1371/journal.pone.0062470
Epub:
Not Epub
Abstract:
Sfrp5 belongs to the family of secreted frizzled related proteins (Sfrp), secreted inhibitors of Wingless-MMTV Integration Site...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stuckenholz C, Lu L, Thakur PC, Choi T-Y, Shin D, Bahary N. Sfrp5 Modulates Both Wnt and BMP Signaling and Regulates Gastrointestinal Organogensis in the Zebrafish, Danio rerio. PLoS ONE. 2013;8(4):e62470. doi:10.1371/journal.pone.0062470.

Sonic hedgehog is indirectly required for intraretinal axon pathfinding by regulating chemokine expression in the optic stalk

Authors:
Stacher Hörndli C, Chien CB
Citation:
Development. 2012 Jul;139(14):2604-13. doi: 10.1242/dev.077594. Epub 2012 Jun 13
Epub:
Not Epub
Abstract:
Successful axon pathfinding requires both correct patterning of tissues, which will later harbor axonal tracts, and precise...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stacher Hörndli C, Chien CB. Sonic hedgehog is indirectly required for intraretinal axon pathfinding by regulating chemokine expression in the optic stalk. Development. 2012 Jul;139(14):2604-13. doi: 10.1242/dev.077594. Epub 2012 Jun 13.

Sox2 and Fgf interact with Atoh1 to promote sensory competence throughout the zebrafish inner ear

Authors:
Sweet EM, Vemaraju S, Riley BB
Citation:
Dev Biol. 2011 Oct 1;358(1):113-21. Epub 2011 Jul 23
Epub:
Not Epub
Abstract:
Atoh1 is required for differentiation of sensory hair cells in the vertebrate inner ear. Moreover, misexpression of Atoh1 is...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sweet EM, Vemaraju S, Riley BB. Sox2 and Fgf interact with Atoh1 to promote sensory competence throughout the zebrafish inner ear. Dev Biol. 2011 Oct 1;358(1):113-21. Epub 2011 Jul 23.

Sp5l is a mediator of Fgf signals in anteroposterior patterning of the neuroectoderm in zebrafish embryo.

Authors:
Sun Z, Zhao J, Zhang Y, Meng A.
Citation:
Dev Dyn. 2006 Nov;235(11):2999-3006.
Epub:
Not Epub
Abstract:
The neuroectoderm is patterned along the anterior-posterior axis in vertebrate embryos. Fgf signals are required to induce the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun Z, Zhao J, Zhang Y, Meng A.. Sp5l is a mediator of Fgf signals in anteroposterior patterning of the neuroectoderm in zebrafish embryo.. Dev Dyn. 2006 Nov;235(11):2999-3006..

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