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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Antisense modulation of RNA processing as a therapeutic approach in cancer therapy

Authors:
Spraggon L, Cartegni L
Citation:
Drug Discovery Today: Therapeutic Strategies. 2013;[Epub ahead of print] doi:10.1016/j.ddstr.2013.06.002
Epub:
Not Epub
Abstract:
Next-generation antisense technologies are re-emerging as viable and powerful approaches to the treatment of several genetic...
Citation Extract:
Spraggon L, Cartegni L. Antisense modulation of RNA processing as a therapeutic approach in cancer therapy. Drug Discovery Today: Therapeutic Strategies. 2013;[Epub ahead of print] doi:10.1016/j.ddstr.2013.06.002.

Antisense properties of morpholino oligomers

Authors:
Summerton J, Weller D
Citation:
Nucleosides Nucleotides 1997;16(7-9): 889-898
Epub:
Not Epub
Abstract:
Morpholino oligomers are third generation antisense agents designed to be cost effective, water soluble and resistant to...
Citation Extract:
Summerton J, Weller D. Antisense properties of morpholino oligomers. Nucleosides Nucleotides 1997;16(7-9): 889-898.

BBS10 encodes a vertebrate-specific chaperonin-like protein and is a major BBS locus

Authors:
Stoetzel C, Laurier V, Davis EE, Muller J, Rix S, Badano JL, Leitch CC, Salem N, Chouery E, Corbani S, Jalk N, Vicaire S, Sarda P, Hamel C, Lacombe D, Holder M, Odent S, Holder S, Brooks AS, Elcioglu NH, Da Silva E, Rossillion B, Sigaudy S, de Ravel TJ, Alan Lewis R, Leheup B, Verloes A, Amati-Bonneau P, Megarbane A, Poch O, Bonneau D, Beales PL, Mandel JL, Katsanis N, Dollfus H
Citation:
Nat Genet. 2006 May;38(5):521-4. Epub 2006 Apr 2.
Epub:
Not Epub
Abstract:
Bardet-Biedl syndrome (BBS) is a genetically heterogeneous ciliopathy. Although nine BBS genes have been cloned, they explain...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stoetzel C, Laurier V, Davis EE, Muller J, Rix S, Badano JL, Leitch CC, Salem N, Chouery E, Corbani S, Jalk N, Vicaire S, Sarda P, Hamel C, Lacombe D, Holder M, Odent S, Holder S, Brooks AS, Elcioglu NH, Da Silva E, Rossillion B, Sigaudy S, de Ravel TJ, Alan Lewis R, Leheup B, Verloes A, Amati-Bonneau P, Megarbane A, Poch O, Bonneau D, Beales PL, Mandel JL, Katsanis N, Dollfus H. BBS10 encodes a vertebrate-specific chaperonin-like protein and is a major BBS locus. Nat Genet. 2006 May;38(5):521-4. Epub 2006 Apr 2..

C-terminal binding proteins are essential pro-survival factors that undergo caspase-dependent downregulation during neuronal apoptosis

Authors:
Stankiewicz TR, Schroeder EK, Kelsey NA, Bouchard RJ, Linseman DA
Citation:
Mol Cell Neurosci. 2013 Jul 13. doi:pii: S1044-7431(13)00070-5. 10.1016/j.mcn.2013.07.004. [Epub ahead of print]
Epub:
Not Epub
Abstract:
C-terminal binding proteins (CtBPs) are transcriptional co-repressors that are subject to proteasome-dependent downregulation...
Citation Extract:
Stankiewicz TR, Schroeder EK, Kelsey NA, Bouchard RJ, Linseman DA. C-terminal binding proteins are essential pro-survival factors that undergo caspase-dependent downregulation during neuronal apoptosis. Mol Cell Neurosci. 2013 Jul 13. doi:pii: S1044-7431(13)00070-5. 10.1016/j.mcn.2013.07.004. [Epub ahead of print].

Ca(2+)/calmodulin-dependent protein kinase phosphatase (CaMKP) is indispensable for normal embryogenesis in zebrafish, Danio rerio

Authors:
Sueyoshi N, Nimura T, Ishida A, Taniguchi T, Yoshimura Y, Ito M, Shigeri Y, Kameshita I
Citation:
Arch Biochem Biophys. 2009 Jun 12. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Ca(2+)/calmodulin-dependent protein kinase phosphatase (CaMKP) dephosphorylates and regulates multifunctional Ca(2+)/calmodulin...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sueyoshi N, Nimura T, Ishida A, Taniguchi T, Yoshimura Y, Ito M, Shigeri Y, Kameshita I. Ca(2+)/calmodulin-dependent protein kinase phosphatase (CaMKP) is indispensable for normal embryogenesis in zebrafish, Danio rerio. Arch Biochem Biophys. 2009 Jun 12. [Epub ahead of print].

Calsenilin is required for endocrine pancreas development in zebrafish.

Authors:
Stetsyuk V, Peers B, Mavropoulos A, Verbruggen V, Thisse B, Thisse C, Motte P, Duvillie B, Scharfmann R
Citation:
Dev Dyn. 2007 Jun;236(6):1517-25.
Epub:
Not Epub
Abstract:
Calsenilin/DREAM/Kchip3 is a neuronal calcium-binding protein. It is a multifunctional protein, mainly expressed in neural...
Organism or Cell Type:
zebrafish
Citation Extract:
Stetsyuk V, Peers B, Mavropoulos A, Verbruggen V, Thisse B, Thisse C, Motte P, Duvillie B, Scharfmann R. Calsenilin is required for endocrine pancreas development in zebrafish.. Dev Dyn. 2007 Jun;236(6):1517-25..

CDX2 in the formation of the trophectoderm lineage in primate embryos

Authors:
Sritanaudomchai H, Sparman M, Tachibana M, Clepper L, Woodward J, Gokhale S, Wolf D, Hennebold J, Hurlbut W, Grompe M, Mitalipov S
Citation:
Dev Biol. 2009 Nov 1;335(1):179-87. Epub 2009 Sep 3
Epub:
Not Epub
Abstract:
The first lineage decision during mammalian development is the establishment of the trophectoderm (TE) and the inner cell mass...
Delivery Method:
Microinjection
Organism or Cell Type:
rhesus macaques oocyte
Citation Extract:
Sritanaudomchai H, Sparman M, Tachibana M, Clepper L, Woodward J, Gokhale S, Wolf D, Hennebold J, Hurlbut W, Grompe M, Mitalipov S. CDX2 in the formation of the trophectoderm lineage in primate embryos. Dev Biol. 2009 Nov 1;335(1):179-87. Epub 2009 Sep 3.

Chemical modifications of antisense morpholino oligomers enhance their efficacy against ebolavirus infection

Authors:
Swenson DL, Warfield KL, Warren TK, Lovejoy C, Hassinger JN, Ruthel G, Blouch RE, Moulton HM, Weller DD, Iversen PL, Bavari S
Citation:
Antimicrob Agents Chemother. 2009 Feb 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Phosphorodiamidate morpholino oligomers (PMO) are uncharged nucleic acid-like molecules designed to inactivate specific gene...
Delivery Method:
various
Organism or Cell Type:
mice, cell cultures
Citation Extract:
Swenson DL, Warfield KL, Warren TK, Lovejoy C, Hassinger JN, Ruthel G, Blouch RE, Moulton HM, Weller DD, Iversen PL, Bavari S. Chemical modifications of antisense morpholino oligomers enhance their efficacy against ebolavirus infection. Antimicrob Agents Chemother. 2009 Feb 17. [Epub ahead of print].

Cholesterol homeostasis in development: the role of Xenopus 7-dehydrocholesterol reductase (Xdhcr7) in neural development.

Authors:
Tadjuidje E, Hollemann T.
Citation:
Dev Dyn. 2006 Aug;235(8):2095-110.Click here to read
Epub:
Not Epub
Abstract:
7-dehydrocholesterol reductase (7-Dhcr) catalyses the final step in the pathway of cholesterol biosynthesis. Human patients...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Tadjuidje E, Hollemann T.. Cholesterol homeostasis in development: the role of Xenopus 7-dehydrocholesterol reductase (Xdhcr7) in neural development.. Dev Dyn. 2006 Aug;235(8):2095-110.Click here to read.

Cloning, localization and functional expression of the electrogenic Na+ bicarbonate cotransporter (NBCe1) from zebrafish

Authors:
Sussman CR, Zhao J, Plata C, Lu J, Daly C, Angle N, Dipiero J, Drummond IA, Liang JO, Boron WF, Romero MF, Chang MH
Citation:
Am J Physiol Cell Physiol. 2009 Jul 22. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Mutations in the electrogenic Na/HCO3(-) cotransporter (NBCe1, SLC4A4) cause severe proximal renal tubular acidosis, glaucoma...
Organism or Cell Type:
zebrafish
Citation Extract:
Sussman CR, Zhao J, Plata C, Lu J, Daly C, Angle N, Dipiero J, Drummond IA, Liang JO, Boron WF, Romero MF, Chang MH. Cloning, localization and functional expression of the electrogenic Na+ bicarbonate cotransporter (NBCe1) from zebrafish. Am J Physiol Cell Physiol. 2009 Jul 22. [Epub ahead of print].

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