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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12497 scientific papers returned from the database with the search filters currently being used below.

Identification, Characterization, and Effects of Xenopus laevis PNAS-4 Gene on Embryonic Development

Authors:
Yan F, Ruan XZ, Yang SH, Yao SH, Zhao XY, Gou LT, Ma FX, Yuan Z, Deng HX, Wei YQ
Citation:
J Biomed Biotechnol. 2010;2010:134764. Epub 2010 May 4.
Epub:
Not Epub
Abstract:
Apoptosis plays an important role in embryonic development. PNAS-4 has been demonstrated to induce apoptosis in several cancer...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yan F, Ruan XZ, Yang SH, Yao SH, Zhao XY, Gou LT, Ma FX, Yuan Z, Deng HX, Wei YQ. Identification, Characterization, and Effects of Xenopus laevis PNAS-4 Gene on Embryonic Development. J Biomed Biotechnol. 2010;2010:134764. Epub 2010 May 4..

Impaired dopaminergic neuron development and locomotor function in zebrafish with loss of pink1 function

Authors:
Xi Y, Ryan J, Noble S, Yu M, Yilbas AE, Ekker M
Citation:
Eur J Neurosci. 2010 Feb 5. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Mutations in the human PTEN-induced kinase 1 (PINK1) gene are linked to recessive familial Parkinson's disease. Animal...
Organism or Cell Type:
zebrafish
Citation Extract:
Xi Y, Ryan J, Noble S, Yu M, Yilbas AE, Ekker M. Impaired dopaminergic neuron development and locomotor function in zebrafish with loss of pink1 function. Eur J Neurosci. 2010 Feb 5. [Epub ahead of print].

Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophy

Authors:
Yamamoto M, Yang G, Hong C, Liu J, Holle E, Yu X, Wagner T, Vatner SF, Sadoshima J.
Citation:
J Clin Invest. 2003 Nov;112(9):1395-406
Epub:
Not Epub
Abstract:
Thioredoxin 1 (Trx1) has redox-sensitive cysteine residues and acts as an antioxidant in cells. However, the extent of Trx1...
Delivery Method:
Osmotic Delivery System
Organism or Cell Type:
cell culture: rat cardiac myocytes
Citation Extract:
Yamamoto M, Yang G, Hong C, Liu J, Holle E, Yu X, Wagner T, Vatner SF, Sadoshima J.. Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophy. J Clin Invest. 2003 Nov;112(9):1395-406.

IQGAP2 is required for the cadherin-mediated cell-to-cell adhesion in Xenopus laevis embryos

Authors:
Yamashiro S, Abe H, Mabuchi I
Citation:
Dev Biol. 2007 Jun 9; [Epub ahead of print]
Epub:
Not Epub
Abstract:
We have previously identified two Xenopus homologues of mammalian IQGAP, XIQGAP1 and XIQGAP2, which show high homology with...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yamashiro S, Abe H, Mabuchi I. IQGAP2 is required for the cadherin-mediated cell-to-cell adhesion in Xenopus laevis embryos. Dev Biol. 2007 Jun 9; [Epub ahead of print].

Isthmin is a novel secreted angiogenesis inhibitor that inhibits tumor growth in mice

Authors:
Xiang W, Ke Z, Zhang Y, Cheng GH, Irwan ID, Sulochana KN, Potturi P, Wang Z, Yang H, Wang J, Zhuo L, Kini RM, Ge R
Citation:
J Cell Mol Med. 2009 Oct 29. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Abstract Antiangiogenesis represents a promising therapeutic strategy for the treatment of various malignances. Isthmin is a...
Organism or Cell Type:
zebrafish
Citation Extract:
Xiang W, Ke Z, Zhang Y, Cheng GH, Irwan ID, Sulochana KN, Potturi P, Wang Z, Yang H, Wang J, Zhuo L, Kini RM, Ge R. Isthmin is a novel secreted angiogenesis inhibitor that inhibits tumor growth in mice. J Cell Mol Med. 2009 Oct 29. [Epub ahead of print].

ISWI contributes to ArsI insulator function in development of the sea urchin

Authors:
Yajima M, Fairbrother WG, Wessel GM
Citation:
Development. 2012 Oct;139(19):3613-22. doi: 10.1242/dev.081828
Epub:
Not Epub
Abstract:
Insulators are genomic elements that regulate transcriptional activity by forming chromatin boundaries. Various DNA insulators...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus
Citation Extract:
Yajima M, Fairbrother WG, Wessel GM. ISWI contributes to ArsI insulator function in development of the sea urchin. Development. 2012 Oct;139(19):3613-22. doi: 10.1242/dev.081828.

JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates

Authors:
Yamanaka H, Moriguchi T, Masuyama N, Kusakabe M, Hanafusa H, Takada R, Takada S, Nishida E
Citation:
EMBO Rep. 2002 Jan;3(1):69-75. Epub 2001 Dec 19
Epub:
Not Epub
Abstract:
Recent genetic studies in Drosophila identified a novel non-canonical Wnt pathway, the planar cell polarity (PCP) pathway, that...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Yamanaka H, Moriguchi T, Masuyama N, Kusakabe M, Hanafusa H, Takada R, Takada S, Nishida E. JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates. EMBO Rep. 2002 Jan;3(1):69-75. Epub 2001 Dec 19.

Krüppel-like is required for nonskeletogenic mesoderm specification in the sea urchin embryo

Authors:
Yamazaki A, Kawabata R, Shiomi K, Tsuchimoto J, Kiyomoto M, Amemiya S, Yamaguchi M
Citation:
Dev Biol. 2007 Dec 7; [Epub ahead of print]
Epub:
Not Epub
Abstract:
The canonical Wnt pathway plays a central role in specifying vegetal cell fate in sea urchin embryos. SpKrl has been cloned as...
Organism or Cell Type:
Sea urchin, Hemicentrotus pulcherrimus
Citation Extract:
Yamazaki A, Kawabata R, Shiomi K, Tsuchimoto J, Kiyomoto M, Amemiya S, Yamaguchi M. Krüppel-like is required for nonskeletogenic mesoderm specification in the sea urchin embryo. Dev Biol. 2007 Dec 7; [Epub ahead of print].

Localization of the Nitric Oxide/cGMP Signaling Pathway-Related Genes and Influences of Morpholino Knock-Down of Soluble Guanylyl Cyclase on Medaka Fish Embryogenesis

Authors:
Yamamoto T, Yao Y, Harumi T, Suzuki N
Citation:
Zoolog Sci 2003;20(2):181-91
Epub:
Not Epub
Abstract:
To better understand the nitric oxide (NO) / cyclic GMP (cGMP) signaling pathway during embryogenesis, we examined the spatial...
Delivery Method:
Microinjection
Organism or Cell Type:
medaka embryos
Citation Extract:
Yamamoto T, Yao Y, Harumi T, Suzuki N. Localization of the Nitric Oxide/cGMP Signaling Pathway-Related Genes and Influences of Morpholino Knock-Down of Soluble Guanylyl Cyclase on Medaka Fish Embryogenesis. Zoolog Sci 2003;20(2):181-91.

Makorin-2 is a neurogenesis inhibitor downstream of PI3k/AKT signal

Authors:
Yang PH, Cheung WK, Peng Y, He ML, Wu GQ, Xie D, Jiang BH, Huang QH, Chen Z, Lin MC, Kung HF
Citation:
J Biol Chem. 2008 Jan 15; [Epub ahead of print]
Epub:
Not Epub
Abstract:
Makorin-2 (MKRN2) belongs to makorin RING zinc-finger gene family which encodes putative ribonucleoproteins. Here we cloned the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Yang PH, Cheung WK, Peng Y, He ML, Wu GQ, Xie D, Jiang BH, Huang QH, Chen Z, Lin MC, Kung HF. Makorin-2 is a neurogenesis inhibitor downstream of PI3k/AKT signal. J Biol Chem. 2008 Jan 15; [Epub ahead of print].

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