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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Sequence Specificity of Alternating Hydroyprolyl/phosphono Peptide Nucleic Acids against Zebrafish Embryo mRNAs
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Citation:
J Drug Target. 2004 Jul;12(6):363-72 Epub:
Not Epub Abstract:
Morpholino phosphorodiamidate (MO) DNA mimics display excellent water solubility and hybridization properties toward DNA and... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Wickstrom E, Choob M, Urtishak KA, Tian X, Sternheim N, Talbot S, Archdeacon J, Efimov VA, Farber SA. Sequence Specificity of Alternating Hydroyprolyl/phosphono Peptide Nucleic Acids against Zebrafish Embryo mRNAs. J Drug Target. 2004 Jul;12(6):363-72. |
Simplified Preparation via Streptavidin of Antisense Oligomers/Carriers Nanoparticles Showing Improved Cellular Delivery in Culture
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Citation:
Bioconjug Chem. 2007 Jul-Aug;18(4):1338-43. Epub 2007 Jul 3. Epub:
Not Epub Abstract:
Objective: Carriers are increasingly now viewed as helpful or even essential to improve cellular uptake in connection with... Delivery Method:
Nanoparticle Citation Extract: Wang Y, Nakamura K, Liu X, Kitamura N, Kubo A, Hnatowich DJ. Simplified Preparation via Streptavidin of Antisense Oligomers/Carriers Nanoparticles Showing Improved Cellular Delivery in Culture. Bioconjug Chem. 2007 Jul-Aug;18(4):1338-43. Epub 2007 Jul 3.. |
SIX2 and BMP4 Mutations Associate With Anomalous Kidney Development
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Citation:
J Am Soc Nephrol. 2008 May;19(5):891-903. Epub 2008 Feb 27. Epub:
Not Epub Abstract:
Renal hypodysplasia (RHD) is characterized by reduced kidney size and/or maldevelopment of the renal tissue following abnormal... Organism or Cell Type:
zebrafish Citation Extract: Weber S, Taylor JC, Winyard P, Baker KF, Sullivan-Brown J, Schild R, Knüppel T, Zurowska AM, Caldas-Alfonso A, Litwin M, Emre S, Ghiggeri GM, Bakkaloglu A, Mehls O, Antignac C; Escape Network, Schaefer F, Burdine RD. SIX2 and BMP4 Mutations Associate With Anomalous Kidney Development. J Am Soc Nephrol. 2008 May;19(5):891-903. Epub 2008 Feb 27.. |
Slit1b-Robo3 Signaling and N-Cadherin Regulate Apical Process Retraction in Developing Retinal Ganglion Cells
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Citation:
J Neurosci. 2012;32(1):223-228 doi:10.1523/JNEUROSCI.2596-11.2012 Epub:
Not Epub Abstract:
When neurons exit the cell cycle after their terminal mitosis, they detach from the apical surface of the neuroepithelium.... Organism or Cell Type:
zebrafish Citation Extract: Wong GKW, Baudet ML, Norden C, Leung L, Harris WA. Slit1b-Robo3 Signaling and N-Cadherin Regulate Apical Process Retraction in Developing Retinal Ganglion Cells. J Neurosci. 2012;32(1):223-228 doi:10.1523/JNEUROSCI.2596-11.2012 . |
SM30 Protein Function during Sea Urchin Larval Spicule Formation
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Citation:
J Struct Biol. 2013;[Epub ahead of print] doi:10.1016/j.jsb.2013.04.001 Epub:
Not Epub Abstract:
A central issue in better understanding the process of biomineralization is to elucidate the function of occluded matrix... Delivery Method:
Microinjection Organism or Cell Type:
sea urchin, Lytechinus pictus and Strongylocentrotus purpuratus Citation Extract: Wilt F, Killian CE, Croker L, Hamilton P. SM30 Protein Function during Sea Urchin Larval Spicule Formation. J Struct Biol. 2013;[Epub ahead of print] doi:10.1016/j.jsb.2013.04.001. |
Specification of posterior hypothalamic neurons requires coordinated activities of Fezf2, Otp, Sim1a and Foxb1.2
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Citation:
Development. 2013;140:1762-1773. doi:10.1242/dev.085357 Epub:
Not Epub Abstract:
The hypothalamus is a key integrative center in the brain that consists of diverse cell types required for a variety of... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Wolf A, Ryu S. Specification of posterior hypothalamic neurons requires coordinated activities of Fezf2, Otp, Sim1a and Foxb1.2. Development. 2013;140:1762-1773. doi:10.1242/dev.085357 . |
Targeted gene knockdown in zebrafish reveals distinct intraembryonic functions for insulin-like growth factor 2 (IGF-II) signaling
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Citation:
Endocrinology. 2009 Sep;150(9):4366-75. Epub 2009 May 14 Epub:
Not Epub Abstract:
Insulin-like growth factor 2 (IGF-II) is the predominant IGF ligand regulating prenatal growth in all vertebrates, including... Organism or Cell Type:
zebrafish Citation Extract: White YA, Kyle JT, Wood AW. Targeted gene knockdown in zebrafish reveals distinct intraembryonic functions for insulin-like growth factor 2 (IGF-II) signaling. Endocrinology. 2009 Sep;150(9):4366-75. Epub 2009 May 14. |
Targeting nuclear RNA for in vivo correction of myotonic dystrophy
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Citation:
Nature. 2012;488:111-5 doi:10.1038/nature11362 Epub:
Not Epub Abstract:
Antisense oligonucleotides (ASOs) hold promise for gene-specific knockdown in diseases that involve RNA or protein gain-of-... Delivery Method:
Injection then electroporation in vivo Organism or Cell Type:
mice Citation Extract: Wheeler T, Leger AJ, Pandey SK, MacLeod AR, Nakamori M, Cheng SH, Wentworth BM, Bennett CF, Thornton CA. Targeting nuclear RNA for in vivo correction of myotonic dystrophy. Nature. 2012;488:111-5 doi:10.1038/nature11362. |
TBX3 Directs Cell-Fate Decision toward Mesendoderm
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Citation:
Stem Cell Rep. 2013;[Epub ahead of print] doi:10.1016/j.stemcr.2013.08.002 Epub:
Not Epub Abstract:
Cell-fate decisions and pluripotency are dependent on networks of key transcriptional regulators. Recent reports demonstrated... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Weidgang CE, Russell R, Tata PR, Kühl SJ, Illing A, Müller M, Lin Q, Brunner C, Boeckers TM, Bauer K, Kartikasari AER, Guo Y, Radenz M, Bernemann C, Weiß M, Seufferlein T, Zenke M, Iacovino M, Kyba M, Schöler HR, Kühl M, Liebau S, Kleger A. TBX3 Directs Cell-Fate Decision toward Mesendoderm. Stem Cell Rep. 2013;[Epub ahead of print] doi:10.1016/j.stemcr.2013.08.002 . |
Teasing out T-box targets in early mesoderm
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Citation:
Curr Opin Genet Dev. 2008 Sep 5. [Epub ahead of print] Epub:
Not Epub Abstract:
T-box transcription factor genes are widely conserved in metazoan development and widely involved in developmental processes.... Delivery Method:
Not Specific Organism or Cell Type:
Zebrafish (lit. review) Citation Extract: Wardle FC, Papaioannou VE. Teasing out T-box targets in early mesoderm. Curr Opin Genet Dev. 2008 Sep 5. [Epub ahead of print]. |