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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12351 scientific papers returned from the database with the search filters currently being used below.
There are 12351 scientific papers returned from the database with the search filters currently being used below.
Notch destabilises maternal β-catenin and restricts dorsal-anterior development in Xenopus
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Citation:
Development. 2011 June 15;138:2567-79. doi: 10.1242/dev.061143 Epub:
Not Epub Abstract:
The blastula chordin- and noggin-expressing centre (BCNE) is the predecessor of the Spemann-Mangold's organiser and also... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Acosta H, López SL, Revinski DR, Carrasco AE. Notch destabilises maternal β-catenin and restricts dorsal-anterior development in Xenopus. Development. 2011 June 15;138:2567-79. doi: 10.1242/dev.061143. |
Notch3 signaling gates cell cycle entry and limits neural stem cell amplification in the adult pallium
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Citation:
Development. 2013 Jul 17. [Epub ahead of print] Epub:
Not Epub Abstract:
Maintaining the homeostasis of germinal zones in adult organs is a fundamental but mechanistically poorly understood process.... Organism or Cell Type:
zebrafish Citation Extract: Alunni A, Krecsmarik M, Bosco A, Galant S, Pan L, Moens CB, Bally-Cuif L. Notch3 signaling gates cell cycle entry and limits neural stem cell amplification in the adult pallium. Development. 2013 Jul 17. [Epub ahead of print]. |
Novel oligonucleotide analogues based on morpholino nucleoside subunits–Antisense technologies: New chemical possibilities
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Citation:
Indian Journal of Chemistry Sect. B. 2009. V. 48B. p. 1721-1726. Epub:
Not Epub Abstract:
Even several decades after pioneer publications there is continued interest in the construction and synthesis of a variety of... Citation Extract: Abramova TV, Kassakin MF, Silnikov VN. Novel oligonucleotide analogues based on morpholino nucleoside subunits–Antisense technologies: New chemical possibilities. Indian Journal of Chemistry Sect. B. 2009. V. 48B. p. 1721-1726.. |
Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor
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Citation:
J Biol Chem. 2001 Dec 14;276(50):47338-51. Epub 2001 Sep 27 Epub:
Not Epub Abstract:
Mammalian apolipoprotein B (apoB) mRNA editing is mediated by a multicomponent holoenzyme containing apobec-1 and ACF. We have... Delivery Method:
Special Delivery Organism or Cell Type:
cell culture: rat hepatoma, McArdle7777 Citation Extract: Anant S, Henderson JO, Mukhopadhyay D, Navaratnam N, Kennedy S, Min J, Davidson NO. Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor. J Biol Chem. 2001 Dec 14;276(50):47338-51. Epub 2001 Sep 27. |
Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β-catenin signalling
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Citation:
EMBO J. 2010 Oct 6;29(19):3236-48. Epub 2010 Aug 24 Epub:
Not Epub Abstract:
Although the transcriptional regulatory events triggered by Oct-3/4 are well documented, understanding the proteomic networks... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Abu-Remaileh M, Gerson A, Farago M, Nathan G, Alkalay I, Zins Rousso S, Gur M, Fainsod A, Bergman Y. Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β-catenin signalling. EMBO J. 2010 Oct 6;29(19):3236-48. Epub 2010 Aug 24. |
P58-A and P58-B: Novel Proteins That Mediate Skeletogenesis in the Sea Urchin Embryo
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Citation:
Dev Biol. 2011 Feb 26. [Epub ahead of print] Epub:
Not Epub Abstract:
During sea urchin embryogenesis, the skeleton is produced by primary mesenchyme cells (PMCs). PMCs undergo a sequence of... Organism or Cell Type:
sea urchin Citation Extract: Adomako-Ankomah A, Ettensohn CA. P58-A and P58-B: Novel Proteins That Mediate Skeletogenesis in the Sea Urchin Embryo. Dev Biol. 2011 Feb 26. [Epub ahead of print]. |
Peptide-based delivery of nucleic acids: design, mechanism of uptake and applications to splice-correcting oligonucleotides
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Citation:
Biochem Soc Trans. 2007 Feb;35(Pt 1):53-5 Epub:
Not Epub Abstract:
CPPs (cell-penetrating peptides) have given rise to much interest for the delivery of biomolecules such as peptides, proteins... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: HeLa AntisenseTest System Citation Extract: Abes S, Moulton H, Turner J, Clair P, Richard JP, Iversen P, Gait MJ, Lebleu B. Peptide-based delivery of nucleic acids: design, mechanism of uptake and applications to splice-correcting oligonucleotides. Biochem Soc Trans. 2007 Feb;35(Pt 1):53-5. |
Pharmacokinetics and biodistribution of phosphorodiamidate morpholino antisense oligomers
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Citation:
Curr Opin Pharmacol. 2005 Oct;5(5):550-5. Epub:
Not Epub Abstract:
The concept of using antisense oligonucleotides to interfere with gene expression offers a new therapeutic strategy for the... Delivery Method:
not applicable Organism or Cell Type:
not applicable Citation Extract: Amantana A, Iversen PL. Pharmacokinetics and biodistribution of phosphorodiamidate morpholino antisense oligomers. Curr Opin Pharmacol. 2005 Oct;5(5):550-5.. |
Pharmacokinetics, Biodistribution, Stability and Toxicity of a Cell-Penetrating Peptide-Morpholino Oligomer Conjugate
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Citation:
Bioconjug Chem. 2007 Jul-Aug;18(4):1325-31. Epub 2007 Jun 21 Epub:
Not Epub Abstract:
Objective: Conjugation of arginine-rich cell-penetrating peptide (CPP) to phosphorodiamidate morpholino oligomers (PMO) has... Delivery Method:
i.v. injection, peptide conjugates vs. bare Morpholino Organism or Cell Type:
Rat Citation Extract: Amantana A, Moulton HM, Cate ML, Reddy MT, Whitehead T, Hassinger JN, Youngblood DS, Iversen PL. Pharmacokinetics, Biodistribution, Stability and Toxicity of a Cell-Penetrating Peptide-Morpholino Oligomer Conjugate. Bioconjug Chem. 2007 Jul-Aug;18(4):1325-31. Epub 2007 Jun 21. |
Planar Cell Polarity Enables Posterior Localization of Nodal Cilia and Left-Right Axis Determination during Mouse and Xenopus Embryogenesis
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Citation:
PLoS One. 2010 Feb 2;5(2):e8999 Epub:
Not Epub Abstract:
Left-right asymmetry in vertebrates is initiated in an early embryonic structure called the ventral node in human and mouse,... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Antic D, Stubbs JL, Suyama K, Kintner C, Scott MP, Axelrod JD. Planar Cell Polarity Enables Posterior Localization of Nodal Cilia and Left-Right Axis Determination during Mouse and Xenopus Embryogenesis. PLoS One. 2010 Feb 2;5(2):e8999. |