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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Xenopus delta-catenin is essential in early embryogenesis and is functionally linked to cadherins and small GTPases

Authors:
Gu D, Sater AK, Ji H, Cho K, Clark M, Stratton SA, Barton MC, Lu Q, McCrea PD
Citation:
J Cell Sci. 2009 Nov 15;122(Pt 22):4049-61. Epub 2009 Oct 20
Epub:
Not Epub
Abstract:
Catenins of the p120 subclass display an array of intracellular localizations and functions. Although the genetic knockout of...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gu D, Sater AK, Ji H, Cho K, Clark M, Stratton SA, Barton MC, Lu Q, McCrea PD. Xenopus delta-catenin is essential in early embryogenesis and is functionally linked to cadherins and small GTPases. J Cell Sci. 2009 Nov 15;122(Pt 22):4049-61. Epub 2009 Oct 20.

Xenopus Meis3 protein lies at a nexus downstream to Zic1 and Pax3 proteins, regulating multiple cell-fates during early nervous system development

Authors:
Gutkovich Y, Ofir R, Elkouby YM, Dibner C, Gefen A, Elias S, Frank D
Citation:
Dev Biol. 2009 Nov 24. [Epub ahead of print]
Epub:
Not Epub
Abstract:
In Xenopus embryos, XMeis3 protein activity is required for normal hindbrain formation. Our results show that XMeis3 protein...
Organism or Cell Type:
Xenopus
Citation Extract:
Gutkovich Y, Ofir R, Elkouby YM, Dibner C, Gefen A, Elias S, Frank D. Xenopus Meis3 protein lies at a nexus downstream to Zic1 and Pax3 proteins, regulating multiple cell-fates during early nervous system development. Dev Biol. 2009 Nov 24. [Epub ahead of print].

Zebrafish microRNA-126 determines hematopoietic cell fate through c-Myb

Authors:
Grabher C, Payne EM, Johnston AB, Bolli N, Lechman E, Dick JE, Kanki JP, Look AT
Citation:
Leukemia. 2011 Mar;25(3):506-14. Epub 2010 Nov 16.
Epub:
Not Epub
Abstract:
Precise regulatory mechanisms are required to appropriately modulate the cellular levels of transcription factors controlling...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Grabher C, Payne EM, Johnston AB, Bolli N, Lechman E, Dick JE, Kanki JP, Look AT. Zebrafish microRNA-126 determines hematopoietic cell fate through c-Myb. Leukemia. 2011 Mar;25(3):506-14. Epub 2010 Nov 16..

Zebrafish second heart field development relies on progenitor specification in anterior lateral plate mesoderm and nkx2.5 function

Authors:
Guner-Ataman B, Paffett-Lugassy N, Adams MS, Nevis KR, Jahangiri L, Obregon P, Kikuchi K, Poss KD, Burns CE, Burns CG
Citation:
Development. 2013;140:1353-1363. doi:10.1242/dev.088351
Epub:
Not Epub
Abstract:
Second heart field (SHF) progenitors perform essential functions during mammalian cardiogenesis. We recently identified a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guner-Ataman B, Paffett-Lugassy N, Adams MS, Nevis KR, Jahangiri L, Obregon P, Kikuchi K, Poss KD, Burns CE, Burns CG. Zebrafish second heart field development relies on progenitor specification in anterior lateral plate mesoderm and nkx2.5 function. Development. 2013;140:1353-1363. doi:10.1242/dev.088351.

α-Actinin-2 deficiency results in sarcomeric defects in zebrafish that cannot be rescued by α-actinin-3 revealing functional differences between sarcomeric isoforms

Authors:
Gupta V, Discenza M, Guyon JR, Kunkel LM, Beggs AH
Citation:
FASEB J. 2012 Jan 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
α-Actinins are actin-binding proteins that can be broadly divided into Ca(2+)-sensitive cytoskeletal and Ca(2+)-insensitive...
Organism or Cell Type:
zebrafish
Citation Extract:
Gupta V, Discenza M, Guyon JR, Kunkel LM, Beggs AH. α-Actinin-2 deficiency results in sarcomeric defects in zebrafish that cannot be rescued by α-actinin-3 revealing functional differences between sarcomeric isoforms. FASEB J. 2012 Jan 17. [Epub ahead of print].

ADAM-17 regulates endothelial cell morphology, proliferation, and in vitro angiogenesis

Authors:
Göoz P, Göoz M, Baldys A, Hoffman S
Citation:
Biochem Biophys Res Commun. 2009 Feb 27;380(1):33-8. Epub 2009 Jan 14
Epub:
Not Epub
Abstract:
Modulation of angiogenesis is a promising approach for treating a wide variety of human diseases including ischemic heart...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HUVEC
Citation Extract:
Göoz P, Göoz M, Baldys A, Hoffman S. ADAM-17 regulates endothelial cell morphology, proliferation, and in vitro angiogenesis. Biochem Biophys Res Commun. 2009 Feb 27;380(1):33-8. Epub 2009 Jan 14.

AHR2 Mutant Reveals Functional Diversity of Aryl Hydrocarbon Receptors in Zebrafish

Authors:
Goodale BC, La Du JK, Bisson WH, Janszen DB, Waters KM,Tanguay RL
Citation:
PLoS ONE. 2012;7(1): e29346
Epub:
Not Epub
Abstract:
The aryl hydrocarbon receptor (AHR) is well known for mediating the toxic effects of TCDD and has been a subject of intense...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Goodale BC, La Du JK, Bisson WH, Janszen DB, Waters KM,Tanguay RL. AHR2 Mutant Reveals Functional Diversity of Aryl Hydrocarbon Receptors in Zebrafish. PLoS ONE. 2012;7(1): e29346.

An essential role for Radar (Gdf6a) in inducing dorsal fate in the zebrafish retina

Authors:
Gosse NJ, Baier H
Citation:
Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2236-41. Epub 2009 Jan 21
Epub:
Not Epub
Abstract:
Retinal ganglion cells form orderly topographic connections with the tectum, establishing a continuous neural representation of...
Organism or Cell Type:
zebrafish
Citation Extract:
Gosse NJ, Baier H. An essential role for Radar (Gdf6a) in inducing dorsal fate in the zebrafish retina. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2236-41. Epub 2009 Jan 21.

atp2b1a regulates Ca(2+) export during differentiation and regeneration of mechanosensory hair cells in zebrafish

Authors:
Go W, Bessarab D, Korzh V
Citation:
Cell Calcium. 2010 Nov 15. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The molecular mechanisms of development of mechanosensory hair cells have been tackled successfully due to in vivo studies in...
Organism or Cell Type:
zebrafish
Citation Extract:
Go W, Bessarab D, Korzh V. atp2b1a regulates Ca(2+) export during differentiation and regeneration of mechanosensory hair cells in zebrafish. Cell Calcium. 2010 Nov 15. [Epub ahead of print].

CC2D2A is mutated in Joubert syndrome and interacts with the ciliopathy-associated basal body protein CEP290

Authors:
Gorden NT, Arts HH, Parisi MA, Coene KL, Letteboer SJ, van Beersum SE, Mans DA, Hikida A, Eckert M, Knutzen D, Alswaid AF, Ozyurek H, Dibooglu S, Otto EA, Liu Y, Davis EE, Hutter CM, Bammler TK, Farin FM, Dorschner M, Topçu M, Zackai EH, Rosenthal P, Owens KN, Katsanis N, Vincent JB, Hildebrandt F, Rubel EW, Raible DW, Knoers NV, Chance PF, Roepman R, Moens CB, Glass IA, Doherty D
Citation:
Am J Hum Genet. 2008 Nov;83(5):559-71. Epub 2008 Oct 23
Epub:
Not Epub
Abstract:
Joubert syndrome and related disorders (JSRD) are primarily autosomal-recessive conditions characterized by hypotonia, ataxia,...
Organism or Cell Type:
zebrafish
Citation Extract:
Gorden NT, Arts HH, Parisi MA, Coene KL, Letteboer SJ, van Beersum SE, Mans DA, Hikida A, Eckert M, Knutzen D, Alswaid AF, Ozyurek H, Dibooglu S, Otto EA, Liu Y, Davis EE, Hutter CM, Bammler TK, Farin FM, Dorschner M, Topçu M, Zackai EH, Rosenthal P, Owens KN, Katsanis N, Vincent JB, Hildebrandt F, Rubel EW, Raible DW, Knoers NV, Chance PF, Roepman R, Moens CB, Glass IA, Doherty D . CC2D2A is mutated in Joubert syndrome and interacts with the ciliopathy-associated basal body protein CEP290. Am J Hum Genet. 2008 Nov;83(5):559-71. Epub 2008 Oct 23.

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