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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Requirement of vasculogenesis and blood circulation in late stages of liver growth in zebrafish

Authors:
Korzh S, Pan X, Garcia-Lecea M, Winata CL, Pan X, Wohland T, Korzh V, Gong Z
Citation:
BMC Dev Biol. 2008 Sep 16;8(1):84. [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: Early events in vertebrate liver development have been the major focus in previous studies, however, late...
Organism or Cell Type:
zebrafish
Citation Extract:
Korzh S, Pan X, Garcia-Lecea M, Winata CL, Pan X, Wohland T, Korzh V, Gong Z. Requirement of vasculogenesis and blood circulation in late stages of liver growth in zebrafish. BMC Dev Biol. 2008 Sep 16;8(1):84. [Epub ahead of print].

Resistance to chemotherapeutic drugs overcome by c-Myc inhibition in a Lewis lung carcinoma murine model

Authors:
Knapp DC, Mata JE, Reddy MT, Devi GR, Iversen PL
Citation:
Anticancer Drugs. 2003 Jan;14(1):39-47
Epub:
Not Epub
Abstract:
Chemotherapy resistance is a significant obstacle in lung cancer therapy, and has been found to frequently correlate with...
Delivery Method:
In vivo: injection and cell culture
Organism or Cell Type:
C57BL/6 mice with LLC cell injected
Citation Extract:
Knapp DC, Mata JE, Reddy MT, Devi GR, Iversen PL. Resistance to chemotherapeutic drugs overcome by c-Myc inhibition in a Lewis lung carcinoma murine model. Anticancer Drugs. 2003 Jan;14(1):39-47.

Retinoid signaling controls mouse pancreatic exocrine lineage selection through epithelial-mesenchymal interactions

Authors:
Kobayashi H, Spilde TL, Bhatia AM, Buckingham RB, Hembree MJ, Prasadan K, Preuett BL, Imamura M, Gittes GK
Citation:
Gastroenterology. 2002 Oct;123(4):1331-40
Epub:
Not Epub
Abstract:
BACKGROUND & AIMS: The early embryonic pancreas gives rise to exocrine (ducts and acini) and endocrine lineages. Control of...
Delivery Method:
oligo bathing
Organism or Cell Type:
Mouse pancreas explants or epithelia
Citation Extract:
Kobayashi H, Spilde TL, Bhatia AM, Buckingham RB, Hembree MJ, Prasadan K, Preuett BL, Imamura M, Gittes GK. Retinoid signaling controls mouse pancreatic exocrine lineage selection through epithelial-mesenchymal interactions. Gastroenterology. 2002 Oct;123(4):1331-40.

RNA modulation, repair and remodeling by splice switching oligonucleotides

Authors:
Kole R, Williams T, Cohen L
Citation:
Acta Biochim Pol. 2004;51(2):373-8
Epub:
Not Epub
Abstract:
Targeting splicing by antisense oligonucleotides allows RNA modifications that are not possible with RNA interference or other...
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Kole R, Williams T, Cohen L. RNA modulation, repair and remodeling by splice switching oligonucleotides. Acta Biochim Pol. 2004;51(2):373-8.

RNA therapeutics: beyond RNA interference and antisense oligonucleotides

Authors:
Kole R, Krainer AR, Altman S
Citation:
Nat Rev Drug Discov. 2012 Jan 20. doi: 10.1038/nrd3625. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Here, we discuss three RNA-based therapeutic technologies exploiting various oligonucleotides that bind to RNA by base pairing...
Organism or Cell Type:
various
Citation Extract:
Kole R, Krainer AR, Altman S. RNA therapeutics: beyond RNA interference and antisense oligonucleotides. Nat Rev Drug Discov. 2012 Jan 20. doi: 10.1038/nrd3625. [Epub ahead of print].

Severe acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity

Authors:
Krähling V, Stein DA, Spiegel M, Weber F, Mühlberger E
Citation:
J Virol. 2009 Mar;83(5):2298-309. doi: 10.1128/JVI.01245-08. Epub 2008 Dec 24. PMID: 19109397; PMCID: PMC2643707
Epub:
Not Epub
Abstract:
In this study, infection of 293/ACE2 cells with SARS-CoV activated several apoptosis-associated events, namely, cleavage of...
Link:
https://journals.asm.org/doi/10.1128/jvi.01245-08
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: 293/ACE2
Citation Extract:
Krähling V, Stein DA, Spiegel M, Weber F, Mühlberger E. Severe acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity. J Virol. 2009 Mar;83(5):2298-309. doi: 10.1128/JVI.01245-08. Epub 2008 Dec 24. PMID: 19109397; PMCID: PMC2643707.

Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration

Authors:
Kizil C, Otto GW, Geisler R, Nüsslein-Volhard C, Antos CL
Citation:
Dev Biol. 2008 Oct 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Two hallmarks of vertebrate epimorphic regeneration are a significant increase in the proliferation of normally quiescent cells...
Organism or Cell Type:
zebrafish
Citation Extract:
Kizil C, Otto GW, Geisler R, Nüsslein-Volhard C, Antos CL. Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration. Dev Biol. 2008 Oct 17. [Epub ahead of print].

Skeletal and pigment cell defects in the lockjaw mutant reveal multiple roles for zebrafish tfap2a in neural crest development

Authors:
Knight RD, Javidan Y, Nelson S, Zhang T, Schilling T
Citation:
Dev Dyn. 2004 Jan;229(1):87-98
Epub:
Not Epub
Abstract:
Members of the AP-2 transcription factor family have critical roles in many aspects of embryonic development. The zebrafish...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Knight RD, Javidan Y, Nelson S, Zhang T, Schilling T. Skeletal and pigment cell defects in the lockjaw mutant reveal multiple roles for zebrafish tfap2a in neural crest development. Dev Dyn. 2004 Jan;229(1):87-98.

Sox9a regulation of ff1a in zebrafish (Danio rerio) suggests an involvement of ff1a in cartilage development

Authors:
Koskinen J, Karlsson J, Olsson PE
Citation:
Comp Biochem Physiol A Mol Integr Physiol. 2008 Oct 12. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The NR5A family of orphan nuclear receptors has been implicated in development of the vertebrate embryo, but their exact role...
Organism or Cell Type:
zebrafish
Citation Extract:
Koskinen J, Karlsson J, Olsson PE. Sox9a regulation of ff1a in zebrafish (Danio rerio) suggests an involvement of ff1a in cartilage development. Comp Biochem Physiol A Mol Integr Physiol. 2008 Oct 12. [Epub ahead of print].

Splicing Segregation: The Minor Spliceosome Acts outside the Nucleus and Controls Cell Proliferation

Authors:
König H, Matter N, Bader R, Thiele W, Müller F
Citation:
Cell. 2007 Nov 16;131(4):718-29
Epub:
Not Epub
Abstract:
The functional relevance and the evolution of two parallel mRNA splicing systems in eukaryotes-a major and minor spliceosome...
Delivery Method:
Microinjection in embryos, electroporation in cultures
Organism or Cell Type:
zebrafish and cultures: NIH 3T3, MDA-MB-321 & Hs578T
Citation Extract:
König H, Matter N, Bader R, Thiele W, Müller F. Splicing Segregation: The Minor Spliceosome Acts outside the Nucleus and Controls Cell Proliferation. Cell. 2007 Nov 16;131(4):718-29.

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