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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 273 scientific papers returned from the database with the search filters currently being used below.
There are 273 scientific papers returned from the database with the search filters currently being used below.
Global analysis of polysome-associated mRNA in vesicular stomatitis virus infected cells
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Citation:
PLoS Pathog. 2019;15(6):e1007875. doi:10.1371/journal.ppat.1007875 Epub:
Not Epub Abstract:
Infection of mammalian cells with vesicular stomatitis virus (VSV) results in the inhibition of cellular translation while... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: HeLa Citation Extract: Neidermyer WJ Jr, Whelan SPJ. Global analysis of polysome-associated mRNA in vesicular stomatitis virus infected cells. PLoS Pathog. 2019;15(6):e1007875. doi:10.1371/journal.ppat.1007875. |
AcrAB-TolC Inhibition by Peptide-conjugated Phosphorodiamidate Morpholino Oligomers Restores Antibiotic Activity in vitro and in vivo
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Citation:
ACS Infect Dis. 2019 May 23. doi: 10.1021/acsinfecdis.9b00123. [Epub ahead of print] Epub:
Yes Abstract:
Overexpression of bacterial efflux pumps are a driver of increasing antibiotic resistance in gram-negative pathogens. The AcrAB... Delivery Method:
peptide-linked Organism or Cell Type:
Enterobacteriaceae strains, Klebsiella pneumoniae, Pseudomonas aeruginosa Citation Extract: Sturge CR, Felder-Scott CF, Pifer R, Pybus C, Jain R, Geller B, Greenberg D. AcrAB-TolC Inhibition by Peptide-conjugated Phosphorodiamidate Morpholino Oligomers Restores Antibiotic Activity in vitro and in vivo. ACS Infect Dis. 2019 May 23. doi: 10.1021/acsinfecdis.9b00123. [Epub ahead of print]. |
Scavenger receptor class A1 mediates uptake of morpholino antisense oligonucleotide into dystrophic skeletal muscle
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Citation:
Mol Ther Nucl Acids. 2019 Jan 25;14:520-535. doi: 10.1016/j.omtn.2019.01.008. Epub:
Not Epub Abstract:
Exon-skipping using phosphorodiamidate morpholino oligomers (PMOs) is a promising treatment strategy for Duchenne muscular... Delivery Method:
peptide-linked, cell bathing Organism or Cell Type:
mice mdx62, cell culture: H2K-mdx 52 myoblasts Citation Extract: Miyatake S, Mizobe Y, Tsoumpra M, Lim KRQ, Hara Y, Shabanpoor F, Yokota T, Takeda S, Aoki Y. Scavenger receptor class A1 mediates uptake of morpholino antisense oligonucleotide into dystrophic skeletal muscle. Mol Ther Nucl Acids. 2019 Jan 25;14:520-535. doi: 10.1016/j.omtn.2019.01.008. . |
Comprehensive RNA-Sequencing Analysis in Serum and Muscle Reveals Novel Small RNA Signatures with Biomarker Potential for DMD
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Citation:
Mol Ther Nucleic Acids. 2018 Dec 7;13:1-15. doi: 10.1016/j.omtn.2018.08.005. Epub 2018 Aug 17 Epub:
Not Epub Abstract:
Extracellular small RNAs (sRNAs), including microRNAs (miRNAs), are promising biomarkers for diseases such as Duchenne muscular... Delivery Method:
peptide-linked Organism or Cell Type:
mice Citation Extract: Coenen-Stass AML, Sork H, Gatto S, Godfrey C, Bhomra A, Krjutškov K, Hart JR, Westholm JO, O'Donovan L, Roos A, Lochmüller H, Puri PL, El Andaloussi S, Wood MJA, Roberts TC. Comprehensive RNA-Sequencing Analysis in Serum and Muscle Reveals Novel Small RNA Signatures with Biomarker Potential for DMD. Mol Ther Nucleic Acids. 2018 Dec 7;13:1-15. doi: 10.1016/j.omtn.2018.08.005. Epub 2018 Aug 17. |
Embryonic myosin is a regeneration marker to monitor utrophin based therapies for DMD
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Citation:
Hum Mol Genet. 2018;ddy353 doi:10.1093/hmg/ddy353 Epub:
Yes Abstract:
Duchenne muscular dystrophy (DMD) is a lethal, X-linked muscle-wasting disease caused by lack of the cytoskeletal protein... Delivery Method:
peptide-linked Organism or Cell Type:
mice mdx Citation Extract: Guiraud S, Edwards B, Squire SE, Moir L, Berg A, Babbs A, Ramadan N, Wood MJ, Davies KE. Embryonic myosin is a regeneration marker to monitor utrophin based therapies for DMD. Hum Mol Genet. 2018;ddy353 doi:10.1093/hmg/ddy353 . |
Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment
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Citation:
Hum Mol Genet. 2018 Oct 2. doi: 10.1093/hmg/ddy346. [Epub ahead of print] Epub:
Yes Abstract:
Duchenne muscular dystrophy (DMD) is caused by loss of dystrophin protein, leading to progressive muscle weakness and premature... Delivery Method:
peptide-linked Organism or Cell Type:
mice mdx Citation Extract: Betts CA, McClorey G, Healicon R, Hammond SM, Manzano R, Muses S, Ball V, Godfrey C, Merritt TM, Westering T, O'Donovan L, Wells KE, Gait MJ, Wells DJ, Tyler D, Wood MJ. Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment. Hum Mol Genet. 2018 Oct 2. doi: 10.1093/hmg/ddy346. [Epub ahead of print]. |
Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments
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Citation:
mBio. 2018;9:e02290-17. doi:10.1128/mBio.02290-17 Epub:
Not Epub Abstract:
RNA viruses that replicate in the cell cytoplasm typically concentrate their replication machinery within specialized... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: Vero Citation Extract: Heinrich BS, Maliga Z, Stein DA, Hyman AA, Whelan SPJ. Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments. mBio. 2018;9:e02290-17. doi:10.1128/mBio.02290-17. |
In Vivo Evaluation of Multiple Exon Skipping with Peptide-PMOs in Cardiac and Skeletal Muscles in Dystrophic Dogs
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Citation:
Methods Mol Biol. 2018;1828:365-379. doi: 10.1007/978-1-4939-8651-4_23 Epub:
Not Epub Abstract:
Exon skipping is an emerging approach to treating Duchenne muscular dystrophy (DMD), one of the most common lethal genetic... Delivery Method:
peptide-linked Organism or Cell Type:
Canis familiaris (dog) Citation Extract: Maruyama R, Aoki Y, Takeda S, Yokota T. In Vivo Evaluation of Multiple Exon Skipping with Peptide-PMOs in Cardiac and Skeletal Muscles in Dystrophic Dogs. Methods Mol Biol. 2018;1828:365-379. doi: 10.1007/978-1-4939-8651-4_23. |
A Novel Zebrafish Model for Assessing In Vivo Delivery of Morpholino Oligomers
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Citation:
Methods Mol Biol. 2018;1828:293-306. doi: 10.1007/978-1-4939-8651-4_18 Epub:
Not Epub Abstract:
Morpholino oligomers have great therapeutic potential for treatment of a broad range of human diseases, including viral,... Delivery Method:
peptide-linked Organism or Cell Type:
zebrafish Citation Extract: Kim J, Clark K, Barton C, Tanguay R, Moulton H. A Novel Zebrafish Model for Assessing In Vivo Delivery of Morpholino Oligomers. Methods Mol Biol. 2018;1828:293-306. doi: 10.1007/978-1-4939-8651-4_18. |
Skipping of Duplicated Dystrophin Exons: In Vitro Induction and Assessment
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Citation:
Methods Mol Biol. 2018;1828:219-228. doi: 10.1007/978-1-4939-8651-4_13 Epub:
Not Epub Abstract:
Duplications of one or more dystrophin exons that disrupt the reading frame account for about 15% of all Duchenne cases, and... Delivery Method:
peptide-linked Citation Extract: Greer K, Fletcher S, Wilton SD. Skipping of Duplicated Dystrophin Exons: In Vitro Induction and Assessment. Methods Mol Biol. 2018;1828:219-228. doi: 10.1007/978-1-4939-8651-4_13. |