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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 273 scientific papers returned from the database with the search filters currently being used below.

Pharmacokinetics, Biodistribution, Stability and Toxicity of a Cell-Penetrating Peptide-Morpholino Oligomer Conjugate

Authors:
Amantana A, Moulton HM, Cate ML, Reddy MT, Whitehead T, Hassinger JN, Youngblood DS, Iversen PL
Citation:
Bioconjug Chem. 2007 Jul-Aug;18(4):1325-31. Epub 2007 Jun 21
Epub:
Not Epub
Abstract:
Objective: Conjugation of arginine-rich cell-penetrating peptide (CPP) to phosphorodiamidate morpholino oligomers (PMO) has...
Link:
https://pubs.acs.org/doi/10.1021/bc070060v
Delivery Method:
i.v. injection, peptide conjugates vs. bare Morpholino
Organism or Cell Type:
Rat
Citation Extract:
Amantana A, Moulton HM, Cate ML, Reddy MT, Whitehead T, Hassinger JN, Youngblood DS, Iversen PL. Pharmacokinetics, Biodistribution, Stability and Toxicity of a Cell-Penetrating Peptide-Morpholino Oligomer Conjugate. Bioconjug Chem. 2007 Jul-Aug;18(4):1325-31. Epub 2007 Jun 21.

Splice Redirection as a Convenient Assay to Monitor CPP-ON Efficiency and Mechanism

Authors:
Abes R, Arzumanov AA, Saleh AF, Said Hassane F, Gait MJ, Lebleu B
Citation:
Methods Mol Biol. 2011;683:307-20
Epub:
Not Epub
Abstract:
Several strategies based on synthetic oligonucleotides (ON) have been proposed to control gene expression. As for most...
Delivery Method:
peptide-coupled
Citation Extract:
Abes R, Arzumanov AA, Saleh AF, Said Hassane F, Gait MJ, Lebleu B. Splice Redirection as a Convenient Assay to Monitor CPP-ON Efficiency and Mechanism. Methods Mol Biol. 2011;683:307-20.

Vectorization of morpholino oligomers by the (R-Ahx-R)(4) peptide allows efficient splicing correction in the absence of endosomolytic agents

Authors:
Abes S, Moulton HM, Clair P, Prevot P, Youngblood DS, Wu RP, Iversen PL, Lebleu B
Citation:
J Control Release. 2006 Dec 1;116(3):304-13. Epub 2006 Sep 30.
Epub:
Not Epub
Abstract:
The efficient and non-toxic nuclear delivery of steric-block oligonucleotides (ON) is a prerequisite for therapeutic strategies...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0168365906004603
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: HeLa AntisenseTest System
Citation Extract:
Abes S, Moulton HM, Clair P, Prevot P, Youngblood DS, Wu RP, Iversen PL, Lebleu B. Vectorization of morpholino oligomers by the (R-Ahx-R)(4) peptide allows efficient splicing correction in the absence of endosomolytic agents. J Control Release. 2006 Dec 1;116(3):304-13. Epub 2006 Sep 30..

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