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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 273 scientific papers returned from the database with the search filters currently being used below.
There are 273 scientific papers returned from the database with the search filters currently being used below.
Inhibition of norovirus replication by morpholino oligomers targeting the 5'-end of the genome
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Citation:
Virology. 2008 Oct 25;380(2):328-37. doi: 10.1016/j.virol.2008.08.007. Epub 2008 Sep 9. Epub:
Not Epub Abstract:
Noroviruses are an important cause of non-bacterial epidemic gastroenteritis, but no specific antiviral therapies are available... Delivery Method:
peptide-coupled Organism or Cell Type:
virus: norovirus Citation Extract: Bok K, Cavanaugh VJ, Matson DO, González-Molleda L, Chang KO, Zintz C, Smith AW, Iversen P, Green KY, Campbell AE. Inhibition of norovirus replication by morpholino oligomers targeting the 5'-end of the genome. Virology. 2008 Oct 25;380(2):328-37. doi: 10.1016/j.virol.2008.08.007. Epub 2008 Sep 9. . |
Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment
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Citation:
Mol Ther Nucleic Acids. 2012;[Epub ahead of print] http://dx.doi.org/10.1038/mtna.2012.30 Epub:
Not Epub Abstract:
Antisense oligonucleotides (AOs) are currently the most promising therapeutic intervention for Duchenne muscular dystrophy (DMD... Delivery Method:
peptide-coupled Organism or Cell Type:
mice (mdx), cultured mdx myotubes Citation Extract: Betts C, Saleh A, Arzumanov A, Hammond S, Godfrey C, Coursindel T, Gait M, Wood M. Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment. Mol Ther Nucleic Acids. 2012;[Epub ahead of print] http://dx.doi.org/10.1038/mtna.2012.30. |
Reverse genetics technology for Rift Valley fever virus: current and future applications for the development of therapeutics and vaccines
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Citation:
Antiviral Res. 2009 Nov;84(2):101-18. Epub 2009 Aug 12. Review Epub:
Not Epub Abstract:
The advent of reverse genetics technology has revolutionized the study of RNA viruses, making it possible to manipulate their... Delivery Method:
peptide-coupled Citation Extract: Bouloy M, Flick R. Reverse genetics technology for Rift Valley fever virus: current and future applications for the development of therapeutics and vaccines. Antiviral Res. 2009 Nov;84(2):101-18. Epub 2009 Aug 12. Review. |
Gene selective mRNA cleavage inhibits the development of Plasmodium falciparum
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Citation:
PNAS. 2012;[Epub ahead of print] doi:10.1073/pnas.1203516109 Epub:
Not Epub Abstract:
Unique peptide-morpholino oligomer (PMO) conjugates have been designed to bind and promote the cleavage of specific mRNA as a... Delivery Method:
peptide-coupled Organism or Cell Type:
Plasmodium falciparum Citation Extract: Augagneur Y, Wesolowski D, Tae HS, Altman S, Mamoun CB. Gene selective mRNA cleavage inhibits the development of Plasmodium falciparum. PNAS. 2012;[Epub ahead of print] doi:10.1073/pnas.1203516109 . |
Arginine-rich cell penetrating peptides: Design, structure-activity, and applications to alter pre-mRNA splicing by steric-block oligonucleotides
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Citation:
J Pept Sci. 2008 Jan 30; [Epub ahead of print] Epub:
Not Epub Abstract:
Rerouting the splicing machinery with steric-block oligonucleotides (ON) might lead to new therapeutic strategies in the... Delivery Method:
peptide-coupled Citation Extract: Abes R, Arzumanov A, Moulton H, Abes S, Ivanova G, Gait MJ, Iversen P, Lebleu B. Arginine-rich cell penetrating peptides: Design, structure-activity, and applications to alter pre-mRNA splicing by steric-block oligonucleotides. J Pept Sci. 2008 Jan 30; [Epub ahead of print] . |
Cell-penetrating-peptide-based delivery of oligonucleotides: an overview
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Citation:
Biochem Soc Trans. 2007 Aug;35(Pt 4):775-9 Epub:
Not Epub Abstract:
Cationic CPPs (cell-penetrating peptides) have been used largely for intracellular delivery of low-molecular-mass drugs,... Delivery Method:
peptide-coupled Citation Extract: Abes R, Arzumanov AA, Moulton HM, Abes S, Ivanova GD, Iversen PL, Gait MJ, Lebleu B. Cell-penetrating-peptide-based delivery of oligonucleotides: an overview. Biochem Soc Trans. 2007 Aug;35(Pt 4):775-9. |
Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies
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Citation:
Nucleic Acids Res. 2008 Nov;36(20):6343-54. Epub 2008 Sep 16 Epub:
Not Epub Abstract:
Redirecting the splicing machinery through the hybridization of high affinity, RNase H- incompetent oligonucleotide analogs... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: HeLa AntisenseTest System Citation Extract: Abes R, Moulton HM, Clair P, Yang ST, Abes S, Melikov K, Prevot P, Youngblood DS, Iversen PL, Chernomordik LV, Lebleu B. Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies. Nucleic Acids Res. 2008 Nov;36(20):6343-54. Epub 2008 Sep 16. |
Inhibition of infectious haematopoietic necrosis virus in cell cultures with peptide-conjugated morpholino oligomers
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Citation:
J Fish Dis. 2005 Jul;28(7):399-410 Epub:
Not Epub Abstract:
Delivery of phosphorodiamidate morpholino oligomers (PMO) into fish cells in vitro and tissues in vivo was examined. Uptake was... Delivery Method:
peptide-coupled Organism or Cell Type:
Fish virus: infectious haematopoietic necrosis virus Citation Extract: Alonso M, Stein DA, Thomann E, Moulton HM, Leong JC, Iversen P, Mourich DV. Inhibition of infectious haematopoietic necrosis virus in cell cultures with peptide-conjugated morpholino oligomers. J Fish Dis. 2005 Jul;28(7):399-410. |
Inhibition of Japanese encephalitis virus replication in cultured cells and mice by a peptide-conjugated morpholino oligomer
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Citation:
J Antimicrob Chemother. 2010 May;65(5):953-61. doi: 10.1093/jac/dkq074. Epub 2010 Mar 18. PMID: 20299495; PMCID: PMC7109675 Epub:
Not Epub Abstract:
Background Japanese encephalitis virus (JEV) has a significant impact on public health throughout Asia, and there is a pressing... Delivery Method:
peptide-coupled Organism or Cell Type:
mice and cell culture: Vero, Neuro2A and J774E cells Citation Extract: Anantpadma M, Stein DA, Vrati S. Inhibition of Japanese encephalitis virus replication in cultured cells and mice by a peptide-conjugated morpholino oligomer. J Antimicrob Chemother. 2010 May;65(5):953-61. doi: 10.1093/jac/dkq074. Epub 2010 Mar 18. PMID: 20299495; PMCID: PMC7109675. |
Peptide-based delivery of nucleic acids: design, mechanism of uptake and applications to splice-correcting oligonucleotides
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Citation:
Biochem Soc Trans. 2007 Feb;35(Pt 1):53-5 Epub:
Not Epub Abstract:
CPPs (cell-penetrating peptides) have given rise to much interest for the delivery of biomolecules such as peptides, proteins... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: HeLa AntisenseTest System Citation Extract: Abes S, Moulton H, Turner J, Clair P, Richard JP, Iversen P, Gait MJ, Lebleu B. Peptide-based delivery of nucleic acids: design, mechanism of uptake and applications to splice-correcting oligonucleotides. Biochem Soc Trans. 2007 Feb;35(Pt 1):53-5. |