You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 273 scientific papers returned from the database with the search filters currently being used below.
There are 273 scientific papers returned from the database with the search filters currently being used below.
Inhibition of porcine reproductive and respiratory syndrome virus infection in piglets by a peptide-conjugated morpholino oligomer
|
Citation:
Antiviral Res. 2011 Jul;91(1):36-42. doi: 10.1016/j.antiviral.2011.04.012. Epub 2011 Apr 30. PMID: 21554902 Epub:
Not Epub Abstract:
Porcine reproductive and respiratory syndrome (PRRS) causes substantial economic losses to the swine industry in many countries... Delivery Method:
Peptide-coupled intranasal Organism or Cell Type:
pig Citation Extract: Opriessnig T, Patel D, Wang R, Halbur PG, Meng XJ, Stein DA, Zhang YJ. Inhibition of porcine reproductive and respiratory syndrome virus infection in piglets by a peptide-conjugated morpholino oligomer. Antiviral Res. 2011 Jul;91(1):36-42. doi: 10.1016/j.antiviral.2011.04.012. Epub 2011 Apr 30. PMID: 21554902. |
Antisense Morpholino-Oligomers Directed against the 5' End of the Genome Inhibit Coronavirus Proliferation and Growth
|
Citation:
J Virol. 2004 Jun;78(11):5891-5899 Epub:
Not Epub Abstract:
Conjugation of a peptide related to the human immunodeficiency virus type 1 Tat represents a novel method for delivery of... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: mouse astrocytoma DBT Citation Extract: Neuman BW, Stein DA, Kroeker AD, Paulino AD, Moulton HM, Iversen PL, Buchmeier MJ. Antisense Morpholino-Oligomers Directed against the 5' End of the Genome Inhibit Coronavirus Proliferation and Growth. J Virol. 2004 Jun;78(11):5891-5899. |
Antisense Targeting of cFLIP Sensitizes Activated T Cells to Undergo Apoptosis and Desensitizes Responses to Contact Dermatitis
|
Citation:
J Invest Dermatol. 2009 Feb 19. [Epub ahead of print] Epub:
Not Epub Abstract:
Contact dermatitis is the result of inflammatory responses mediated by hapten-specific activated CD8+ and CD4+ T cells.... Delivery Method:
peptide-coupled Organism or Cell Type:
mice and cell culture: T cells Citation Extract: Mourich DV, Jendrzejewski JL, Marshall NB, Hinrichs DJ, Iversen PL, Brand RM. Antisense Targeting of cFLIP Sensitizes Activated T Cells to Undergo Apoptosis and Desensitizes Responses to Contact Dermatitis. J Invest Dermatol. 2009 Feb 19. [Epub ahead of print]. |
Arginine-rich Peptide conjugation to morpholino oligomers: effects on antisense activity and specificity
|
Citation:
Bioconjug Chem. 2005 Jul-Aug;16(4):959-66 Epub:
Not Epub Abstract:
Noncharged antisense compounds, such as phosphorodiamidate morpholino oligomers (PMOs), do not readily enter mammalian cells in... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: HeLa Antisense Test System, others Citation Extract: Nelson MH, Stein DA, Kroeker AD, Hatlevig SA, Iversen PL, Moulton HM. Arginine-rich Peptide conjugation to morpholino oligomers: effects on antisense activity and specificity. Bioconjug Chem. 2005 Jul-Aug;16(4):959-66. |
Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors
|
Citation:
Antimicrob Agents Chemother. 2011 Oct;55(10):4631-8. doi: 10.1128/AAC.00650-11. Epub 2011 Aug 8. PMID: 21825302; PMCID: PMC3186971 Epub:
Not Epub Abstract:
Members of the Arenaviridae are a threat to public health and can cause meningitis and hemorrhagic fever, yet treatment options... Delivery Method:
peptide-coupled Organism or Cell Type:
virus: Junín, Tacaribe, Pichinde and Lymphocytic Choriomeningitis arenavirus-infected cell cultures Citation Extract: Neuman BW, Bederka LH, Stein DA, Ting JP, Moulton HM, Buchmeier MJ. Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors. Antimicrob Agents Chemother. 2011 Oct;55(10):4631-8. doi: 10.1128/AAC.00650-11. Epub 2011 Aug 8. PMID: 21825302; PMCID: PMC3186971. |
Inhibition of KSHV-associated lymphoma engraftment in SCID mouse by morpholino oligomers
|
Citation:
Infect Agent Cancer. 2010; 5(Suppl 1): A40. Epub 2010 Oct 11 Epub:
Not Epub Abstract:
Kaposi’s sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8, is associated with several malignant... Delivery Method:
peptide-coupled Organism or Cell Type:
mouse, SCID Citation Extract: Nan Y, Patel D, Zhang Y. Inhibition of KSHV-associated lymphoma engraftment in SCID mouse by morpholino oligomers. Infect Agent Cancer. 2010; 5(Suppl 1): A40. Epub 2010 Oct 11. |
Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers
|
Citation:
J Virol. 2005 Aug;79(15):9665-76 Epub:
Not Epub Abstract:
The recently emerged severe acute respiratory syndrome coronavirus (SARS-CoV) is a potent pathogen of humans and is capable of... Delivery Method:
peptide-coupled Organism or Cell Type:
SARS virus Citation Extract: Neuman BW, Stein DA, Kroeker AD, Churchill MJ, Kim AM, Kuhn P, Dawson P, Moulton HM, Bestwick RK, Iversen PL, Buchmeier MJ. Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers. J Virol. 2005 Aug;79(15):9665-76. |
Peptide-morpholino conjugate: a promising therapeutic for Duchenne muscular dystrophy
|
Citation:
Ann N Y Acad Sci. 2009 Sep;1175:55-60 Epub:
Not Epub Abstract:
Steric-blocking oligos can correct reading frame errors or skip premature termination codons. For Duchenne muscular dystrophy (... Delivery Method:
peptide-coupled Organism or Cell Type:
mice, mdx Citation Extract: Moulton HM, Wu B, Jearawiriyapaisarn N, Sazani P, Lu QL, Kole R. Peptide-morpholino conjugate: a promising therapeutic for Duchenne muscular dystrophy. Ann N Y Acad Sci. 2009 Sep;1175:55-60. |
Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo
|
Citation:
Biochem Soc Trans. 2007 Aug;35(Pt 4):826-8 Epub:
Not Epub Abstract:
The cellular uptake of PMOs (phosphorodiamidate morpholino oligomers) can be enhanced by their conjugation to arginine-rich... Delivery Method:
peptide-coupled Organism or Cell Type:
mice (mdx), dog myoblasts Citation Extract: Moulton HM, Fletcher S, Neuman BW, McClorey G, Stein DA, Abes S, Wilton SD, Buchmeier MJ, Lebleu B, Iversen PL. Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo. Biochem Soc Trans. 2007 Aug;35(Pt 4):826-8. |
Cell-penetrating peptides enhance systemic delivery of antisense morpholino oligomers
|
Citation:
Methods Mol Biol. 2012;867:407-14 Epub:
Not Epub Abstract:
Exon-skipping efficacy of phosphorodiamidate morpholino oligomers (Morpholinos) has been demonstrated in a proof-of-concept... Delivery Method:
peptide-coupled Organism or Cell Type:
mice, mdx and utrophin/dystrophin dKO Citation Extract: Moulton HM. Cell-penetrating peptides enhance systemic delivery of antisense morpholino oligomers. Methods Mol Biol. 2012;867:407-14. |