You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 261 scientific papers returned from the database with the search filters currently being used below.
There are 261 scientific papers returned from the database with the search filters currently being used below.
Expression Analysis in Multiple Muscle Groups and Serum Reveals Complexity in the MicroRNA Transcriptome of the mdx Mouse with Implications for Therapy
|
Citation:
Mol Ther Nucleic Acids. 2012;[Epub ahead of print] doi:/10.1038/mtna.2012.26 Epub:
Not Epub Abstract:
MicroRNAs (miRNAs) are a class of small RNAs that regulate gene expression and are implicated in wide-ranging cellular... Delivery Method:
peptide-coupled Organism or Cell Type:
mice, mdx Citation Extract: Roberts TC, Blomberg KEM, McClorey G, Andaloussi SEL, Godfrey C, Betts C, Coursindel T, Gait MJ, Edvard S, Wood MJA. Expression Analysis in Multiple Muscle Groups and Serum Reveals Complexity in the MicroRNA Transcriptome of the mdx Mouse with Implications for Therapy. Mol Ther Nucleic Acids. 2012;[Epub ahead of print] doi:/10.1038/mtna.2012.26. |
Bacterial Resistance to Antisense Peptide-Phosphorodiamidate Morpholino Oligomers
|
Citation:
Antimicrob Agents Chemother. 2012 Sep 17. [Epub ahead of print] Epub:
Not Epub Abstract:
Peptide phosphorodiamidate morpholino oligomers (PPMO) are synthetic DNA mimics that bind complementary RNA and inhibit... Delivery Method:
peptide-coupled Organism or Cell Type:
Escherichia coli Citation Extract: Puckett SE, Reese KA, Mitev GM, Mullen V, Johnson RC, Pomraning KR, Mellbye BL, Tilley LD, Iversen PL, Freitag M, Geller BL. Bacterial Resistance to Antisense Peptide-Phosphorodiamidate Morpholino Oligomers. Antimicrob Agents Chemother. 2012 Sep 17. [Epub ahead of print]. |
Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers
|
Citation:
Virology. 2008 Jul 5;376(2):357-70. Epub 2008 May 12. Epub:
Not Epub Abstract:
The genus Alphavirus contains members that threaten human health, both as natural pathogens and as potential biological weapons... Delivery Method:
peptide-coupled Organism or Cell Type:
mice Citation Extract: Paessler S, Rijnbrand R, Stein DA, Ni H, Yun NE, Dziuba N, Borisevich V, Seregin A, Ma Y, Blouch R, Iversen PL, Zacks MA. Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers. Virology. 2008 Jul 5;376(2):357-70. Epub 2008 May 12.. |
Morpholino oligomer-mediated protection of porcine pulmonary alveolar macrophages from arterivirus-induced cell death
|
Citation:
Antivir Ther. 2009;14(7):899-909 Epub:
Not Epub Abstract:
BACKGROUND: Porcine reproductive and respiratory syndrome (PRRS) causes extensive economic losses in the swine industry.... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: porcine pulmonary alveolar macrophages Citation Extract: Patel D, Stein DA, Zhang YJ. Morpholino oligomer-mediated protection of porcine pulmonary alveolar macrophages from arterivirus-induced cell death. Antivir Ther. 2009;14(7):899-909. |
Peptide Conjugated Phosphorodiamidate Morpholino Oligomers Increase Survival of Mice Challenged with Ames Bacillus anthracis
|
Citation:
Nucleic Acid Therapeutics. 2012;[Epub ahead of print] doi:10.1089/nat.2012.0362 Epub:
Not Epub Abstract:
Targeting bacterial essential genes using antisense phosphorodiamidate morpholino oligomers (PMOs) represents an important... Delivery Method:
peptide-coupled Organism or Cell Type:
Bacillus anthracis Citation Extract: Panchal RG, Geller BL, Mellbye B, Lane D, Iversen PL, Bavari S. Peptide Conjugated Phosphorodiamidate Morpholino Oligomers Increase Survival of Mice Challenged with Ames Bacillus anthracis. Nucleic Acid Therapeutics. 2012;[Epub ahead of print] doi:10.1089/nat.2012.0362. |
Peptide-conjugated morpholino oligomers inhibit porcine reproductive and respiratory syndrome virus replication
|
Citation:
Antiviral Res. 2008 Feb;77(2):95-107. Epub 2007 Oct 4 Epub:
Not Epub Abstract:
Porcine reproductive and respiratory syndrome (PRRS) has been devastating the global swine industry for more than a decade, and... Delivery Method:
peptide-coupled Organism or Cell Type:
Porcine reproductive and resporatory syndrome virus (PRRSV) in cell cultures Citation Extract: Patel D, Opriessnig T, Stein DA, Halbur PG, Meng XJ, Iversen PL, Zhang YJ. Peptide-conjugated morpholino oligomers inhibit porcine reproductive and respiratory syndrome virus replication. Antiviral Res. 2008 Feb;77(2):95-107. Epub 2007 Oct 4. |
Reduced expression of CD45 protein tyrosine phosphatase provides protection against anthrax pathogenesis
|
Citation:
J Biol Chem. 2009 May 8;284(19):12874-85. Epub 2009 Mar 6. Epub:
Not Epub Abstract:
The modulation of cellular processes by small molecule inhibitors, gene inactivation or targeted knock-down strategies combined... Delivery Method:
peptide-coupled Organism or Cell Type:
mice and cell culture: macrophage J774A.1 cells Citation Extract: Panchal RG, Ulrich RL, Bradfute SB, Lane D, Ruthel G, Kenny TA, Iversen PL, Anderson AO, Gussio R, Raschke WC, Bavari S. Reduced expression of CD45 protein tyrosine phosphatase provides protection against anthrax pathogenesis. J Biol Chem. 2009 May 8;284(19):12874-85. Epub 2009 Mar 6.. |
Emerging drugs for respiratory syncytial virus infection
|
Citation:
Expert Opin Emerg Drugs. 2009 Jun;14(2):207-17 Epub:
Not Epub Abstract:
Although respiratory syncytial virus (RSV) was discovered > 40 years ago, treatment remains largely supportive. There are no... Delivery Method:
peptide-coupled Organism or Cell Type:
mice and cell culture Citation Extract: Olszewska W, Openshaw P. Emerging drugs for respiratory syncytial virus infection. Expert Opin Emerg Drugs. 2009 Jun;14(2):207-17. |
Inhibition of porcine reproductive and respiratory syndrome virus infection in piglets by a peptide-conjugated morpholino oligomer
|
Citation:
Antiviral Res. 2011 Apr 30. [Epub ahead of print] Epub:
Not Epub Abstract:
Porcine reproductive and respiratory syndrome (PRRS) causes substantial economic losses to the swine industry in many countries... Delivery Method:
Peptide-coupled intranasal Organism or Cell Type:
pig Citation Extract: Opriessnig T, Patel D, Wang R, Halbur PG, Meng XJ, Stein DA, Zhang YJ. Inhibition of porcine reproductive and respiratory syndrome virus infection in piglets by a peptide-conjugated morpholino oligomer. Antiviral Res. 2011 Apr 30. [Epub ahead of print]. |
Antisense Morpholino-Oligomers Directed against the 5' End of the Genome Inhibit Coronavirus Proliferation and Growth
|
Citation:
J Virol. 2004 Jun;78(11):5891-5899 Epub:
Not Epub Abstract:
Conjugation of a peptide related to the human immunodeficiency virus type 1 Tat represents a novel method for delivery of... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: mouse astrocytoma DBT Citation Extract: Neuman BW, Stein DA, Kroeker AD, Paulino AD, Moulton HM, Iversen PL, Buchmeier MJ. Antisense Morpholino-Oligomers Directed against the 5' End of the Genome Inhibit Coronavirus Proliferation and Growth. J Virol. 2004 Jun;78(11):5891-5899. |