You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 273 scientific papers returned from the database with the search filters currently being used below.

Co-selection of West Nile virus nucleotides that confer resistance to an antisense oligomer while maintaining long-distance RNA/RNA base pairings

Authors:
Zhang B, Dong H, Stein DA, Shi PY
Citation:
Virology. 2008 Dec 5;382(1):98-106. Epub 2008 Oct 7.
Epub:
Not Epub
Abstract:
West Nile virus (WNV) genome cyclization is mediated by two pairs of long-distance RNA/RNA interactions: the 5'CS/3'...
Delivery Method:
peptide-coupled
Organism or Cell Type:
West Nile Virus
Citation Extract:
Zhang B, Dong H, Stein DA, Shi PY. Co-selection of West Nile virus nucleotides that confer resistance to an antisense oligomer while maintaining long-distance RNA/RNA base pairings. Virology. 2008 Dec 5;382(1):98-106. Epub 2008 Oct 7..

Construction of a novel chimera consisting of a chelator-containing Tat peptide conjugated to a morpholino antisense oligomer for technetium-99m labeling and accelerating cellular kinetics

Authors:
Zhang YM, Tung CH, He J, Liu N, Yanachkov I, Liu G, Rusckowski M, Vanderheyden JL
Citation:
Nucl Med Biol. 2006 Feb;33(2):263-9
Epub:
Not Epub
Abstract:
The attempt to target the limited copies of messenger RNA (mRNA) in vivo with radiolabeled nucleobase oligomers as antisense...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture
Citation Extract:
Zhang YM, Tung CH, He J, Liu N, Yanachkov I, Liu G, Rusckowski M, Vanderheyden JL. Construction of a novel chimera consisting of a chelator-containing Tat peptide conjugated to a morpholino antisense oligomer for technetium-99m labeling and accelerating cellular kinetics. Nucl Med Biol. 2006 Feb;33(2):263-9.

Curing of HeLa Cells Persistently Infected with Equine Arteritis Virus by a Peptide-conjugated Morpholino Oligomer

Authors:
Zhang J, Stein DA, Timoney PJ, Balasuriya UB
Citation:
Virus Res. 2010 Jun;150(1-2):138-42. doi: 10.1016/j.virusres.2010.02.013. Epub 2010 Mar 3. PMID: 20206215; PMCID: PMC7114391
Epub:
Not Epub
Abstract:
A significant consequence of equine arteritis virus (EAV) infection of horses is persistence of the virus in a variable...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: HeLa with equine arteritis viral infection
Citation Extract:
Zhang J, Stein DA, Timoney PJ, Balasuriya UB. Curing of HeLa Cells Persistently Infected with Equine Arteritis Virus by a Peptide-conjugated Morpholino Oligomer. Virus Res. 2010 Jun;150(1-2):138-42. doi: 10.1016/j.virusres.2010.02.013. Epub 2010 Mar 3. PMID: 20206215; PMCID: PMC7114391.

Inhibition of coxsackievirus B3 in cell cultures and in mice by peptide-conjugated morpholino oligomers targeting the internal ribosome entry site.

Authors:
Yuan J, Stein DA, Lim T, Qiu D, Coughlin S, Liu Z, Wang Y, Bouch R, Moulton HM, Iversen PL, Yang D
Citation:
J Virol. 2006 Dec;80(23):11510-9. Epub 2006 Sep 20.
Epub:
Not Epub
Abstract:
Coxsackievirus B3 (CVB3) is a primary cause of viral myocarditis, yet no effective therapeutic against CVB3 is available....
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice - A/J [H-2a] (Jackson Laboratory)
Citation Extract:
Yuan J, Stein DA, Lim T, Qiu D, Coughlin S, Liu Z, Wang Y, Bouch R, Moulton HM, Iversen PL, Yang D. Inhibition of coxsackievirus B3 in cell cultures and in mice by peptide-conjugated morpholino oligomers targeting the internal ribosome entry site.. J Virol. 2006 Dec;80(23):11510-9. Epub 2006 Sep 20..

Inhibition of primary effusion lymphoma engraftment in SCID mice by morpholino oligomers against early lytic genes of Kaposi's sarcoma-associated herpesvirus

Authors:
Zhang YJ, Patel D, Nan Y, Fan S
Citation:
Antivir Ther. 2011;16(5):657-66
Epub:
Not Epub
Abstract:
BACKGROUND: Kaposi's sarcoma-associated herpesvirus (KSHV) is associated with several malignant diseases, including Kaposi...
Delivery Method:
peptide-coupled
Organism or Cell Type:
virus: Kaposi's sarcoma-associated herpesvirus in SCID mice
Citation Extract:
Zhang YJ, Patel D, Nan Y, Fan S. Inhibition of primary effusion lymphoma engraftment in SCID mice by morpholino oligomers against early lytic genes of Kaposi's sarcoma-associated herpesvirus. Antivir Ther. 2011;16(5):657-66.

Inhibition of replication and transcription activator and latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus by morpholino oligomers

Authors:
Zhang YJ, Wang KY, Stein DA, Patel D, Watkins R, Moulton HM, Iversen PL, Matson DO
Citation:
Antiviral Res. 2007 Jan;73(1):12-23. Epub 2006 Jun 14.
Epub:
Not Epub
Abstract:
Kaposi's sarcoma-associated herpesvirus (KSHV) is associated with Kaposi's sarcoma and primary effusion lymphoma (PEL...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: PEL cells
Citation Extract:
Zhang YJ, Wang KY, Stein DA, Patel D, Watkins R, Moulton HM, Iversen PL, Matson DO. Inhibition of replication and transcription activator and latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus by morpholino oligomers. Antiviral Res. 2007 Jan;73(1):12-23. Epub 2006 Jun 14..

Suppression of porcine reproductive and respiratory syndrome virus replication by morpholino antisense oligomers

Authors:
Zhang YJ, Stein DA, Fan SM, Wang KY, Kroeker AD, Meng XJ, Iversen PL, Matson DO
Citation:
Vet Microbiol. 2006 Oct 31;117(2-4):117-29. Epub 2006 Jul 12.
Epub:
Not Epub
Abstract:
Porcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent of a contagious disease characterized by...
Delivery Method:
peptide-coupled
Organism or Cell Type:
Cell Culture: CRL11171 cells
Citation Extract:
Zhang YJ, Stein DA, Fan SM, Wang KY, Kroeker AD, Meng XJ, Iversen PL, Matson DO. Suppression of porcine reproductive and respiratory syndrome virus replication by morpholino antisense oligomers. Vet Microbiol. 2006 Oct 31;117(2-4):117-29. Epub 2006 Jul 12..

A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice

Authors:
Yin H, Moulton HM, Betts C, Seow Y, Boutilier J, Iverson PL, Wood MJ
Citation:
Hum Mol Genet. 2009 Aug 18. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is caused by mutations in the DMD gene that abolish the synthesis of dystrophin protein....
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice, mdx
Citation Extract:
Yin H, Moulton HM, Betts C, Seow Y, Boutilier J, Iverson PL, Wood MJ. A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice. Hum Mol Genet. 2009 Aug 18. [Epub ahead of print].

Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function

Authors:
Yin H, Moulton HM, Seow Y, Boyd C, Boutilier J, Iverson P, Wood MJ
Citation:
Hum Mol Genet. 2008 Sep 10. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Antisense oligonucleotides (AOs) have the potential to induce functional dystrophin protein expression via exon skipping by...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice, mdx
Citation Extract:
Yin H, Moulton HM, Seow Y, Boyd C, Boutilier J, Iverson P, Wood MJ. Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function. Hum Mol Genet. 2008 Sep 10. [Epub ahead of print].

Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency

Authors:
Yin H, Boisguerin P, Moulton HM, Betts C, Seow Y, Boutilier J, Wang Q, Walsh A, Lebleu B, Wood MJ
Citation:
Mol Ther Nucleic Acids. 2013 Sep 24;2:e124. doi: 10.1038/mtna.2013.51
Epub:
Not Epub
Abstract:
We have recently reported that cell-penetrating peptides (CPPs) and novel chimeric peptides containing CPP (referred as B...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice, mdx
Citation Extract:
Yin H, Boisguerin P, Moulton HM, Betts C, Seow Y, Boutilier J, Wang Q, Walsh A, Lebleu B, Wood MJ. Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency. Mol Ther Nucleic Acids. 2013 Sep 24;2:e124. doi: 10.1038/mtna.2013.51.

Pages