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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 273 scientific papers returned from the database with the search filters currently being used below.
There are 273 scientific papers returned from the database with the search filters currently being used below.
Silencing of GRA10 protein expression inhibits Toxoplasma gondii intracellular growth and development
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Citation:
Parasitol Int. 2014 May 13. pii: S1383-5769(14)00059-2. doi: 10.1016/j.parint.2014.05.001. [Epub ahead of print] Epub:
Yes Abstract:
Toxoplasma gondii dense granule proteins (GRAs) are secreted abundantly in both the tachyzoite and bradyzoite stages of the... Delivery Method:
peptide-linked Organism or Cell Type:
Toxoplasma gondii Citation Extract: Witola WH, Bauman B, McHugh M, Matthews K. Silencing of GRA10 protein expression inhibits Toxoplasma gondii intracellular growth and development. Parasitol Int. 2014 May 13. pii: S1383-5769(14)00059-2. doi: 10.1016/j.parint.2014.05.001. [Epub ahead of print]. |
Effective dystrophin restoration by a novel muscle-homing peptide-morpholino conjugate in dystrophin-deficient mdx mice
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Citation:
Mol Ther. 2014 Apr 15. doi: 10.1038/mt.2014.63. [Epub ahead of print] Epub:
Yes Abstract:
Antisense oligonucleotide (AO) - mediated splice correction therapy for Duchenne muscular dystrophy (DMD) has shown huge... Delivery Method:
peptide-linked Organism or Cell Type:
mdx mice Citation Extract: Gao X, Zhao J, Han G, Zhang Y, Dong X, Cao L, Wang Q, Moulton HM, Yin H. Effective dystrophin restoration by a novel muscle-homing peptide-morpholino conjugate in dystrophin-deficient mdx mice. Mol Ther. 2014 Apr 15. doi: 10.1038/mt.2014.63. [Epub ahead of print]. |
Targeted Exon Skipping to Correct Exon Duplications in the Dystrophin Gene
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Citation:
Molec Ther Nucleic Acids. 2014;3,e155. doi:10.1038/mtna.2014.8 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy is a severe muscle-wasting disease caused by mutations in the dystrophin gene that ablate... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: primary fibroblasts induced myogenic Citation Extract: Greer KL, Lochmüller H, Flanigan K, Fletcher S, Wilton SD. Targeted Exon Skipping to Correct Exon Duplications in the Dystrophin Gene. Molec Ther Nucleic Acids. 2014;3,e155. doi:10.1038/mtna.2014.8. |
Multicellular Tumor Spheroids as a Model for Assessing Delivery of Oligonucleotides in Three Dimensions
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Citation:
Mol Ther Nucleic Acids. 2014;3:e153. doi:10.1038/mtna.2014.5 Epub:
Not Epub Abstract:
Oligonucleotides have shown promise in selectively manipulating gene expression in vitro, but that success has not translated... Delivery Method:
peptide-linked Organism or Cell Type:
culture: multicellular tumor spheroid Citation Extract: Carver K, Ming X, Juliano RL. Multicellular Tumor Spheroids as a Model for Assessing Delivery of Oligonucleotides in Three Dimensions. Mol Ther Nucleic Acids. 2014;3:e153. doi:10.1038/mtna.2014.5. |
Assessment of RT-qPCR Normalization Strategies for Accurate Quantification of Extracellular microRNAs in Murine Serum
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Citation:
PLoS ONE. 2014;9(2):e89237. doi:10.1371/journal.pone.0089237 Epub:
Not Epub Abstract:
Extracellular microRNAs (miRNAs) are under investigation as minimally-invasive biomarkers for a wide range of disease... Delivery Method:
peptide-linked Organism or Cell Type:
mouse Citation Extract: Roberts TC, Coenen-Stass AML, Wood MJA. Assessment of RT-qPCR Normalization Strategies for Accurate Quantification of Extracellular microRNAs in Murine Serum. PLoS ONE. 2014;9(2):e89237. doi:10.1371/journal.pone.0089237. |
Antisense suppression of donor splice site mutations in the dystrophin gene transcript
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Citation:
Mol Genet Genomic Med. 2013 Sep;1(3):162-73. doi: 10.1002/mgg3.19. Epub 2013 Jun 13 Epub:
Not Epub Abstract:
We describe two donor splice site mutations, affecting dystrophin exons 16 and 45 that led to Duchenne muscular dystrophy (DMD... Delivery Method:
peptide-linked Organism or Cell Type:
Primary DMD human cells underwent forced myogenesis Citation Extract: Fletcher S, Meloni PL, Johnsen RD, Wong BL, Muntoni F, Wilton SD. Antisense suppression of donor splice site mutations in the dystrophin gene transcript. Mol Genet Genomic Med. 2013 Sep;1(3):162-73. doi: 10.1002/mgg3.19. Epub 2013 Jun 13. |
Antibiotics Present and Future
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Citation:
FEBS Letters. 2013;[Epub ahead of print] doi:10.1016/j.febslet.2013.10.048 Epub:
Not Epub Abstract:
Here we make a brief survey of the present state of antibiotic research and use. We also describe a novel antibiotic that... Delivery Method:
peptide-linked Organism or Cell Type:
Plasmodium falciparum, bacteria Citation Extract: Altman S. Antibiotics Present and Future. FEBS Letters. 2013;[Epub ahead of print] doi:10.1016/j.febslet.2013.10.048. |
Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy
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Citation:
J Control Release. 2010 Jan 4;141(1):42-51. doi: 10.1016/j.jconrel.2009.08.028. Epub 2009 Sep 8 Epub:
Not Epub Abstract:
In recent years, oligonucleotide-based molecules have been intensely used to modulate gene expression. All these molecules... Delivery Method:
peptide Organism or Cell Type:
cell culture Citation Extract: Lehto T, Abes R, Oskolkov N, Suhorutsenko J, Copolovici DM, Mäger I, Viola JR, Simonson OE, Ezzat K, Guterstam P, Eriste E, Smith CI, Lebleu B, Samir El Andaloussi, Langel U. Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy. J Control Release. 2010 Jan 4;141(1):42-51. doi: 10.1016/j.jconrel.2009.08.028. Epub 2009 Sep 8. |
Gene-Silencing Antisense Oligomers Inhibit Acinetobacter Growth In Vitro and In Vivo
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Citation:
J Infect Dis. 2013;[Epub ahead of print] doi:10.1093/infdis/jit460 Epub:
Not Epub Abstract:
Background. Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMOs) are synthetic DNA/RNA analogues that silence... Delivery Method:
Peptide-coupled Organism or Cell Type:
Mice Citation Extract: Geller BL, Marshall-Batty K, Schnell FJ, McKnight MM, Iversen PL, Greenberg DE. Gene-Silencing Antisense Oligomers Inhibit Acinetobacter Growth In Vitro and In Vivo. J Infect Dis. 2013;[Epub ahead of print] doi:10.1093/infdis/jit460 . |
Blockade of viral interleukin-6 expression of Kaposi's sarcoma-associated herpesvirus
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Citation:
Mol Cancer Ther. 2008 Mar;7(3):712-20 Epub:
Not Epub Abstract:
Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8, is associated with several malignant... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: PEL Citation Extract: Zhang YJ, Bonaparte RS, Patel D, Stein DA, Iversen PL. Blockade of viral interleukin-6 expression of Kaposi's sarcoma-associated herpesvirus. Mol Cancer Ther. 2008 Mar;7(3):712-20. |