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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 258 scientific papers returned from the database with the search filters currently being used below.
There are 258 scientific papers returned from the database with the search filters currently being used below.
Morpholino oligomer-mediated protection of porcine pulmonary alveolar macrophages from arterivirus-induced cell death
Citation:
Antivir Ther. 2009;14(7):899-909 Epub:
Not Epub Abstract:
BACKGROUND: Porcine reproductive and respiratory syndrome (PRRS) causes extensive economic losses in the swine industry.... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: porcine pulmonary alveolar macrophages Citation Extract: Patel D, Stein DA, Zhang YJ. Morpholino oligomer-mediated protection of porcine pulmonary alveolar macrophages from arterivirus-induced cell death. Antivir Ther. 2009;14(7):899-909. |
Peptide Conjugated Phosphorodiamidate Morpholino Oligomers Increase Survival of Mice Challenged with Ames Bacillus anthracis
Citation:
Nucleic Acid Therapeutics. 2012;[Epub ahead of print] doi:10.1089/nat.2012.0362 Epub:
Not Epub Abstract:
Targeting bacterial essential genes using antisense phosphorodiamidate morpholino oligomers (PMOs) represents an important... Delivery Method:
peptide-coupled Organism or Cell Type:
Bacillus anthracis Citation Extract: Panchal RG, Geller BL, Mellbye B, Lane D, Iversen PL, Bavari S. Peptide Conjugated Phosphorodiamidate Morpholino Oligomers Increase Survival of Mice Challenged with Ames Bacillus anthracis. Nucleic Acid Therapeutics. 2012;[Epub ahead of print] doi:10.1089/nat.2012.0362. |
Peptide-conjugated morpholino oligomers inhibit porcine reproductive and respiratory syndrome virus replication
Citation:
Antiviral Res. 2008 Feb;77(2):95-107. Epub 2007 Oct 4 Epub:
Not Epub Abstract:
Porcine reproductive and respiratory syndrome (PRRS) has been devastating the global swine industry for more than a decade, and... Delivery Method:
peptide-coupled Organism or Cell Type:
Porcine reproductive and resporatory syndrome virus (PRRSV) in cell cultures Citation Extract: Patel D, Opriessnig T, Stein DA, Halbur PG, Meng XJ, Iversen PL, Zhang YJ. Peptide-conjugated morpholino oligomers inhibit porcine reproductive and respiratory syndrome virus replication. Antiviral Res. 2008 Feb;77(2):95-107. Epub 2007 Oct 4. |
Reduced expression of CD45 protein tyrosine phosphatase provides protection against anthrax pathogenesis
Citation:
J Biol Chem. 2009 May 8;284(19):12874-85. Epub 2009 Mar 6. Epub:
Not Epub Abstract:
The modulation of cellular processes by small molecule inhibitors, gene inactivation or targeted knock-down strategies combined... Delivery Method:
peptide-coupled Organism or Cell Type:
mice and cell culture: macrophage J774A.1 cells Citation Extract: Panchal RG, Ulrich RL, Bradfute SB, Lane D, Ruthel G, Kenny TA, Iversen PL, Anderson AO, Gussio R, Raschke WC, Bavari S. Reduced expression of CD45 protein tyrosine phosphatase provides protection against anthrax pathogenesis. J Biol Chem. 2009 May 8;284(19):12874-85. Epub 2009 Mar 6.. |
Emerging drugs for respiratory syncytial virus infection
Citation:
Expert Opin Emerg Drugs. 2009 Jun;14(2):207-17 Epub:
Not Epub Abstract:
Although respiratory syncytial virus (RSV) was discovered > 40 years ago, treatment remains largely supportive. There are no... Delivery Method:
peptide-coupled Organism or Cell Type:
mice and cell culture Citation Extract: Olszewska W, Openshaw P. Emerging drugs for respiratory syncytial virus infection. Expert Opin Emerg Drugs. 2009 Jun;14(2):207-17. |
Inhibition of porcine reproductive and respiratory syndrome virus infection in piglets by a peptide-conjugated morpholino oligomer
Citation:
Antiviral Res. 2011 Apr 30. [Epub ahead of print] Epub:
Not Epub Abstract:
Porcine reproductive and respiratory syndrome (PRRS) causes substantial economic losses to the swine industry in many countries... Delivery Method:
Peptide-coupled intranasal Organism or Cell Type:
pig Citation Extract: Opriessnig T, Patel D, Wang R, Halbur PG, Meng XJ, Stein DA, Zhang YJ. Inhibition of porcine reproductive and respiratory syndrome virus infection in piglets by a peptide-conjugated morpholino oligomer. Antiviral Res. 2011 Apr 30. [Epub ahead of print]. |
Antisense Morpholino-Oligomers Directed against the 5' End of the Genome Inhibit Coronavirus Proliferation and Growth
Citation:
J Virol. 2004 Jun;78(11):5891-5899 Epub:
Not Epub Abstract:
Conjugation of a peptide related to the human immunodeficiency virus type 1 Tat represents a novel method for delivery of... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: mouse astrocytoma DBT Citation Extract: Neuman BW, Stein DA, Kroeker AD, Paulino AD, Moulton HM, Iversen PL, Buchmeier MJ. Antisense Morpholino-Oligomers Directed against the 5' End of the Genome Inhibit Coronavirus Proliferation and Growth. J Virol. 2004 Jun;78(11):5891-5899. |
Antisense Targeting of cFLIP Sensitizes Activated T Cells to Undergo Apoptosis and Desensitizes Responses to Contact Dermatitis
Citation:
J Invest Dermatol. 2009 Feb 19. [Epub ahead of print] Epub:
Not Epub Abstract:
Contact dermatitis is the result of inflammatory responses mediated by hapten-specific activated CD8+ and CD4+ T cells.... Delivery Method:
peptide-coupled Organism or Cell Type:
mice and cell culture: T cells Citation Extract: Mourich DV, Jendrzejewski JL, Marshall NB, Hinrichs DJ, Iversen PL, Brand RM. Antisense Targeting of cFLIP Sensitizes Activated T Cells to Undergo Apoptosis and Desensitizes Responses to Contact Dermatitis. J Invest Dermatol. 2009 Feb 19. [Epub ahead of print]. |
Arginine-rich Peptide conjugation to morpholino oligomers: effects on antisense activity and specificity
Citation:
Bioconjug Chem. 2005 Jul-Aug;16(4):959-66 Epub:
Not Epub Abstract:
Noncharged antisense compounds, such as phosphorodiamidate morpholino oligomers (PMOs), do not readily enter mammalian cells in... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: HeLa Antisense Test System, others Citation Extract: Nelson MH, Stein DA, Kroeker AD, Hatlevig SA, Iversen PL, Moulton HM. Arginine-rich Peptide conjugation to morpholino oligomers: effects on antisense activity and specificity. Bioconjug Chem. 2005 Jul-Aug;16(4):959-66. |
Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors
Citation:
Antimicrob Agents Chemother. 2011 Aug 8. [Epub ahead of print] Epub:
Not Epub Abstract:
Members of the Arenaviridae are a threat to public health and can cause meningitis and hemorrhagic fever, yet treatment options... Delivery Method:
peptide-coupled Organism or Cell Type:
virus: Junín, Tacaribe, Pichinde and Lymphocytic Choriomeningitis arenavirus-infected cell cultures Citation Extract: Neuman BW, Bederka LH, Stein DA, Ting JP, Moulton HM, Buchmeier MJ. Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors. Antimicrob Agents Chemother. 2011 Aug 8. [Epub ahead of print]. |