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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 260 scientific papers returned from the database with the search filters currently being used below.
There are 260 scientific papers returned from the database with the search filters currently being used below.
Multicellular Tumor Spheroids as a Model for Assessing Delivery of Oligonucleotides in Three Dimensions
Citation:
Mol Ther Nucleic Acids. 2014;3:e153. doi:10.1038/mtna.2014.5 Epub:
Not Epub Abstract:
Oligonucleotides have shown promise in selectively manipulating gene expression in vitro, but that success has not translated... Delivery Method:
peptide-linked Organism or Cell Type:
culture: multicellular tumor spheroid Citation Extract: Carver K, Ming X, Juliano RL. Multicellular Tumor Spheroids as a Model for Assessing Delivery of Oligonucleotides in Three Dimensions. Mol Ther Nucleic Acids. 2014;3:e153. doi:10.1038/mtna.2014.5. |
Assessment of RT-qPCR Normalization Strategies for Accurate Quantification of Extracellular microRNAs in Murine Serum
Citation:
PLoS ONE. 2014;9(2):e89237. doi:10.1371/journal.pone.0089237 Epub:
Not Epub Abstract:
Extracellular microRNAs (miRNAs) are under investigation as minimally-invasive biomarkers for a wide range of disease... Delivery Method:
peptide-linked Organism or Cell Type:
mouse Citation Extract: Roberts TC, Coenen-Stass AML, Wood MJA. Assessment of RT-qPCR Normalization Strategies for Accurate Quantification of Extracellular microRNAs in Murine Serum. PLoS ONE. 2014;9(2):e89237. doi:10.1371/journal.pone.0089237. |
Antisense suppression of donor splice site mutations in the dystrophin gene transcript
Citation:
Mol Genet Genomic Med. 2013 Sep;1(3):162-73. doi: 10.1002/mgg3.19. Epub 2013 Jun 13 Epub:
Not Epub Abstract:
We describe two donor splice site mutations, affecting dystrophin exons 16 and 45 that led to Duchenne muscular dystrophy (DMD... Delivery Method:
peptide-linked Organism or Cell Type:
Primary DMD human cells underwent forced myogenesis Citation Extract: Fletcher S, Meloni PL, Johnsen RD, Wong BL, Muntoni F, Wilton SD. Antisense suppression of donor splice site mutations in the dystrophin gene transcript. Mol Genet Genomic Med. 2013 Sep;1(3):162-73. doi: 10.1002/mgg3.19. Epub 2013 Jun 13. |
Antibiotics Present and Future
Citation:
FEBS Letters. 2013;[Epub ahead of print] doi:10.1016/j.febslet.2013.10.048 Epub:
Not Epub Abstract:
Here we make a brief survey of the present state of antibiotic research and use. We also describe a novel antibiotic that... Delivery Method:
peptide-linked Organism or Cell Type:
Plasmodium falciparum, bacteria Citation Extract: Altman S. Antibiotics Present and Future. FEBS Letters. 2013;[Epub ahead of print] doi:10.1016/j.febslet.2013.10.048. |
Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy
Citation:
J Control Release. 2010 Jan 4;141(1):42-51. doi: 10.1016/j.jconrel.2009.08.028. Epub 2009 Sep 8 Epub:
Not Epub Abstract:
In recent years, oligonucleotide-based molecules have been intensely used to modulate gene expression. All these molecules... Delivery Method:
peptide Organism or Cell Type:
cell culture Citation Extract: Lehto T, Abes R, Oskolkov N, Suhorutsenko J, Copolovici DM, Mäger I, Viola JR, Simonson OE, Ezzat K, Guterstam P, Eriste E, Smith CI, Lebleu B, Samir El Andaloussi, Langel U. Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy. J Control Release. 2010 Jan 4;141(1):42-51. doi: 10.1016/j.jconrel.2009.08.028. Epub 2009 Sep 8. |
Gene-Silencing Antisense Oligomers Inhibit Acinetobacter Growth In Vitro and In Vivo
Citation:
J Infect Dis. 2013;[Epub ahead of print] doi:10.1093/infdis/jit460 Epub:
Not Epub Abstract:
Background. Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMOs) are synthetic DNA/RNA analogues that silence... Delivery Method:
Peptide-coupled Organism or Cell Type:
Mice Citation Extract: Geller BL, Marshall-Batty K, Schnell FJ, McKnight MM, Iversen PL, Greenberg DE. Gene-Silencing Antisense Oligomers Inhibit Acinetobacter Growth In Vitro and In Vivo. J Infect Dis. 2013;[Epub ahead of print] doi:10.1093/infdis/jit460 . |
Blockade of viral interleukin-6 expression of Kaposi's sarcoma-associated herpesvirus
Citation:
Mol Cancer Ther. 2008 Mar;7(3):712-20 Epub:
Not Epub Abstract:
Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8, is associated with several malignant... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: PEL Citation Extract: Zhang YJ, Bonaparte RS, Patel D, Stein DA, Iversen PL. Blockade of viral interleukin-6 expression of Kaposi's sarcoma-associated herpesvirus. Mol Cancer Ther. 2008 Mar;7(3):712-20. |
Co-selection of West Nile virus nucleotides that confer resistance to an antisense oligomer while maintaining long-distance RNA/RNA base pairings
Citation:
Virology. 2008 Dec 5;382(1):98-106. Epub 2008 Oct 7. Epub:
Not Epub Abstract:
West Nile virus (WNV) genome cyclization is mediated by two pairs of long-distance RNA/RNA interactions: the 5'CS/3'... Delivery Method:
peptide-coupled Organism or Cell Type:
West Nile Virus Citation Extract: Zhang B, Dong H, Stein DA, Shi PY. Co-selection of West Nile virus nucleotides that confer resistance to an antisense oligomer while maintaining long-distance RNA/RNA base pairings. Virology. 2008 Dec 5;382(1):98-106. Epub 2008 Oct 7.. |
Construction of a novel chimera consisting of a chelator-containing Tat peptide conjugated to a morpholino antisense oligomer for technetium-99m labeling and accelerating cellular kinetics
Citation:
Nucl Med Biol. 2006 Feb;33(2):263-9 Epub:
Not Epub Abstract:
The attempt to target the limited copies of messenger RNA (mRNA) in vivo with radiolabeled nucleobase oligomers as antisense... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture Citation Extract: Zhang YM, Tung CH, He J, Liu N, Yanachkov I, Liu G, Rusckowski M, Vanderheyden JL. Construction of a novel chimera consisting of a chelator-containing Tat peptide conjugated to a morpholino antisense oligomer for technetium-99m labeling and accelerating cellular kinetics. Nucl Med Biol. 2006 Feb;33(2):263-9. |
Curing of HeLa Cells Persistently Infected with Equine Arteritis Virus by a Peptide-conjugated Morpholino Oligomer
Citation:
Virus Res. 2010 Mar 2. [Epub ahead of print] Epub:
Not Epub Abstract:
A significant consequence of equine arteritis virus (EAV) infection of horses is persistence of the virus in a variable... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: HeLa with equine arteritis viral infection Citation Extract: Zhang J, Stein DA, Timoney PJ, Balasuriya UB. Curing of HeLa Cells Persistently Infected with Equine Arteritis Virus by a Peptide-conjugated Morpholino Oligomer. Virus Res. 2010 Mar 2. [Epub ahead of print]. |