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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

microRNA-1 Regulates NCC Migration and Differentiation by Targeting sec63

Authors:
Wang D, Weng Y, Guo S, Qin W, Ni J, Yu L, Zhang Y, Zhao Q, Ben J, Ma J
Citation:
Int J Biol Sci. 2019;15(12):2538-2547. doi:10.7150/ijbs.35357
Epub:
Not Epub
Abstract:
Background/Aims: Neural crest cells play a vital role in craniofacial development, microRNA-1 (miR-1) is essential in...
Link:
https://www.ijbs.com/v15p2538
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang D, Weng Y, Guo S, Qin W, Ni J, Yu L, Zhang Y, Zhao Q, Ben J, Ma J. microRNA-1 Regulates NCC Migration and Differentiation by Targeting sec63. Int J Biol Sci. 2019;15(12):2538-2547. doi:10.7150/ijbs.35357.

Acidified water impairs the lateral line system of zebrafish embryos

Authors:
Lin LY, Hung GY, Yeh YH, Chen SW, Horng JL
Citation:
Aquat Toxicol. 2019 Nov 3;217:105351. doi: 10.1016/j.aquatox.2019.105351. [Epub ahead of print]
Epub:
Yes
Abstract:
Acidification of freshwater ecosystems is recognized as a global environmental problem. However, the influence of acidic water...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0166445X1930284X
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin LY, Hung GY, Yeh YH, Chen SW, Horng JL. Acidified water impairs the lateral line system of zebrafish embryos. Aquat Toxicol. 2019 Nov 3;217:105351. doi: 10.1016/j.aquatox.2019.105351. [Epub ahead of print].

A Hypomorphic Cystathionine ß-Synthase Gene Contributes to Cavefish Eye Loss by Disrupting Optic Vasculature

Authors:
Ma L, Gore AV, Castranova D, Shi J, Ng M, Tomins KA, van der Weele CM, Weinstein BM, Jeffery WR
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/805804
Epub:
Not Epub
Abstract:
Vestigial structures are key indicators of evolutionary descent but the mechanisms underlying their development are poorly...
Link:
https://www.biorxiv.org/content/10.1101/805804v1.full
Delivery Method:
microinjection
Organism or Cell Type:
Astyanax mexicanus (cavefish)
Citation Extract:
Ma L, Gore AV, Castranova D, Shi J, Ng M, Tomins KA, van der Weele CM, Weinstein BM, Jeffery WR. A Hypomorphic Cystathionine ß-Synthase Gene Contributes to Cavefish Eye Loss by Disrupting Optic Vasculature. bioRxiv. 2019;[preprint] doi:10.1101/805804.

NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and X. laevis models

Authors:
Singh MD, Jensen M, Lasser M, Huber E, Yusuff T, Pizzo L, Lifschutz B, Desai I, Kubina A, Yennawar S, Kim S, Iyer J, Rincon-Limas DE, Lowery LA, Girirajan S
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/614750
Epub:
Not Epub
Abstract:
The chromosome 3q29 deletion is associated with a range of neurodevelopmental disorders. Here, we used quantitative methods to...
Link:
https://www.biorxiv.org/content/10.1101/614750v2.full
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Singh MD, Jensen M, Lasser M, Huber E, Yusuff T, Pizzo L, Lifschutz B, Desai I, Kubina A, Yennawar S, Kim S, Iyer J, Rincon-Limas DE, Lowery LA, Girirajan S. NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and X. laevis models. bioRxiv. 2019;[preprint] doi:10.1101/614750 .

Asymmetric Hapln1a drives regionalised cardiac ECM expansion and promotes heart morphogenesis during zebrafish development

Authors:
Derrick CJ, Sánchez-Posada J, Hussein F, Tessadori F, Pollitt EJG, Savage AM, Wilkinson RN, Chico TJ, van Eeden FJ, Bakkers J, Noël ES
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/838128
Epub:
Not Epub
Abstract:
The mature vertebrate heart develops from a simple linear cardiac tube during early development through a series of highly...
Link:
https://www.biorxiv.org/content/10.1101/838128v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Derrick CJ, Sánchez-Posada J, Hussein F, Tessadori F, Pollitt EJG, Savage AM, Wilkinson RN, Chico TJ, van Eeden FJ, Bakkers J, Noël ES. Asymmetric Hapln1a drives regionalised cardiac ECM expansion and promotes heart morphogenesis during zebrafish development. bioRxiv. 2019;[preprint] doi:10.1101/838128 .

Alternative polyadenylation of Pax3 controls muscle stem cell fate and muscle function

Authors:
de Morree A, Klein JDD, Gan Q, Farup J, Urtasun A, Kanugovi A, Bilen B, van Velthoven CTJ, Quarta M, Rando TA
Citation:
Science. 2019 Nov 8;366(6466):734-738. doi: 10.1126/science.aax1694
Epub:
Not Epub
Abstract:
Adult stem cells are essential for tissue homeostasis. In skeletal muscle, muscle stem cells (MuSCs) reside in a quiescent...
Link:
https://science.sciencemag.org/content/366/6466/734
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
de Morree A, Klein JDD, Gan Q, Farup J, Urtasun A, Kanugovi A, Bilen B, van Velthoven CTJ, Quarta M, Rando TA. Alternative polyadenylation of Pax3 controls muscle stem cell fate and muscle function. Science. 2019 Nov 8;366(6466):734-738. doi: 10.1126/science.aax1694.

The role of nitric oxide during embryonic wound healing

Authors:
Abaffy P, Tomankova S, Naraine R, Kubista M, Sindelka R
Citation:
BMC Genomics. 2019 Nov 6;20(1):815. doi: 10.1186/s12864-019-6147-6
Epub:
Not Epub
Abstract:
BACKGROUND: The study of the mechanisms controlling wound healing is an attractive area within the field of biology, with it...
Link:
https://link.springer.com/article/10.1186/s12864-019-6147-6
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Abaffy P, Tomankova S, Naraine R, Kubista M, Sindelka R. The role of nitric oxide during embryonic wound healing. BMC Genomics. 2019 Nov 6;20(1):815. doi: 10.1186/s12864-019-6147-6.

miR-182-5p is an evolutionarily conserved Tbx5 effector that impacts cardiac development and electrical activity in zebrafish

Authors:
Guzzolino E, Pellegrino M, Ahuja N, Garrity D, D'Aurizio R, Groth M, Baumgart M, Hatcher CJ, Mercatanti A, Evangelista M, Ippolito C, Tognoni E, Fukuda R, Lionetti V, Pellegrini M, Cremisi F, Pitto L
Citation:
Cell Mol Life Sci. 2019 Nov 4. doi: 10.1007/s00018-019-03343-7. [Epub ahead of print]
Epub:
Not Epub
Abstract:
To dissect the TBX5 regulatory circuit, we focused on microRNAs (miRNAs) that collectively contribute to make TBX5 a pivotal...
Link:
https://link.springer.com/article/10.1007%2Fs00018-019-03343-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guzzolino E, Pellegrino M, Ahuja N, Garrity D, D'Aurizio R, Groth M, Baumgart M, Hatcher CJ, Mercatanti A, Evangelista M, Ippolito C, Tognoni E, Fukuda R, Lionetti V, Pellegrini M, Cremisi F, Pitto L. miR-182-5p is an evolutionarily conserved Tbx5 effector that impacts cardiac development and electrical activity in zebrafish. Cell Mol Life Sci. 2019 Nov 4. doi: 10.1007/s00018-019-03343-7. [Epub ahead of print].

The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response

Authors:
Seifert LL, Si C, Saha D, Sadic M, de Vries M, Ballentine S, Briley A, Wang G, Valero-Jimenez AM, Mohamed A, Schaefer U, Moulton HM, García-Sastre A, Tripathi S, Rosenberg BR, Dittmann M
Citation:
PLoS Pathog. 2019 Nov 4;15(11):e1007634. doi: 10.1371/journal.ppat.1007634. PMID: 31682641; PMCID: PMC6932815
Epub:
Not Epub
Abstract:
Induction of vast transcriptional programs is a central event of innate host responses to viral infections. Here we report a...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC6932815/
Delivery Method:
intranasal peptide-linked
Organism or Cell Type:
mice
Citation Extract:
Seifert LL, Si C, Saha D, Sadic M, de Vries M, Ballentine S, Briley A, Wang G, Valero-Jimenez AM, Mohamed A, Schaefer U, Moulton HM, García-Sastre A, Tripathi S, Rosenberg BR, Dittmann M. The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response. PLoS Pathog. 2019 Nov 4;15(11):e1007634. doi: 10.1371/journal.ppat.1007634. PMID: 31682641; PMCID: PMC6932815.

A gene-edited mouse model of limb-girdle muscular dystrophy 2C for testing exon skipping

Authors:
Demonbreun AR, Wyatt EJ, Fallon KS, Oosterbaan CC, Page PG, Hadhazy M, Quattrocelli M, Barefield DY, McNally EM
Citation:
Dis Model Mech. 2019 Nov 4;13(2). pii: dmm040832. doi: 10.1242/dmm.040832
Epub:
Not Epub
Abstract:
Limb-girdle muscular dystrophy type 2C is caused by autosomal recessive mutations in the γ-sarcoglycan (SGCG) gene. The most...
Link:
https://dmm.biologists.org/content/13/2/dmm040832
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice 521ΔT
Citation Extract:
Demonbreun AR, Wyatt EJ, Fallon KS, Oosterbaan CC, Page PG, Hadhazy M, Quattrocelli M, Barefield DY, McNally EM. A gene-edited mouse model of limb-girdle muscular dystrophy 2C for testing exon skipping. Dis Model Mech. 2019 Nov 4;13(2). pii: dmm040832. doi: 10.1242/dmm.040832.

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