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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
De novo mutations in FBRSL1 cause a novel recognizable malformation and intellectual disability syndrome
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Citation:
Hum Genet. 2020 May 18. doi: 10.1007/s00439-020-02175-x. Online ahead of print Epub:
Yes Abstract:
We report truncating de novo variants in specific exons of FBRSL1 in three unrelated children with an overlapping syndromic... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Ufartes R, Berger H, Till K, Salinas G, Sturm M, Altmüller J, Nürnberg P, Thiele H, Funke R, Apeshiotis N, Langen H, Wollnik B, Borchers A, Pauli S. De novo mutations in FBRSL1 cause a novel recognizable malformation and intellectual disability syndrome. Hum Genet. 2020 May 18. doi: 10.1007/s00439-020-02175-x. Online ahead of print. |
The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology
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Citation:
Hum Molec Genet. 2020;[Epub ahead of print] doi:10.1093/hmg/ddaa096 Epub:
Yes Abstract:
Mutations of the RNA-granule component TDRD7 (OMIM: 611258) cause pediatric cataract. We applied an integrated approach to... Organism or Cell Type:
Xenopus tropicalis Citation Extract: Barnum CE, Al Saai S, Patel SD, Cheng C, Anand D, Xu X, Dash S, Siddam AD, Glazewski L, Paglione E, Polson SW, Chuma S, Mason RW, Wei S, Batish M, Fowler VM, Lachke SA. The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology. Hum Molec Genet. 2020;[Epub ahead of print] doi:10.1093/hmg/ddaa096. |
RNA structural dynamics regulate early embryogenesis through controlling transcriptome fate and function
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Citation:
Genome Biol. 2020;21(1):120 doi:10.1186/s13059-020-02022-2 Epub:
Not Epub Abstract:
Background: Vertebrate early embryogenesis is initially directed by a set of maternal RNAs and proteins, yet the mechanisms... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shi B, Zhang J, Heng J, Gong J, Zhang T, Li P, Sun B-F, Yang Y, Zhang N, Zhao Y-L, Wang H-L, Liu F, Zhang QC, Yang Y-G. RNA structural dynamics regulate early embryogenesis through controlling transcriptome fate and function. Genome Biol. 2020;21(1):120 doi:10.1186/s13059-020-02022-2. |
Polarized endosome dynamics engage cytosolic Par-3 and dynein during asymmetric division
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.15.098012 Epub:
Not Epub Abstract:
Asymmetric cell division (ACD), which produces two daughters with different fates, is fundamental for generating cellular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhao X, Tong K, Chen X, Yang B, Li Q, Dai Z, Shi X, Seiple I, Huang B, Guo S. Polarized endosome dynamics engage cytosolic Par-3 and dynein during asymmetric division. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.15.098012 . |
Mycobacteria inhibit neutrophil recruitment to avoid neutrophil-assisted killing by macrophages
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Citation:
bioRxiv, 2020;[preprint] doi:10.1101/2020.05.14.096032 Epub:
Not Epub Abstract:
Neutrophils migrate rapidly to sites of bacterial infection where they mount critical first-line defenses. Puzzlingly,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ramakrishnan L, Candel S. Mycobacteria inhibit neutrophil recruitment to avoid neutrophil-assisted killing by macrophages. bioRxiv, 2020;[preprint] doi:10.1101/2020.05.14.096032. |
Functional Characterization of Neurofilament Light Splicing and Misbalance in Zebrafish
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Citation:
Cells. 2020;9(5):1238 doi:10.3390/cells9051238 Epub:
Not Epub Abstract:
Neurofilaments (NFs), a major cytoskeletal component of motor neurons, play a key role in the differentiation, establishment... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Demy DL, Campanari M-L, Munoz-Ruiz R,Durham HD, Gentil B, Kabashi E. Functional Characterization of Neurofilament Light Splicing and Misbalance in Zebrafish. Cells. 2020;9(5):1238 doi:10.3390/cells9051238. |
Dach1 regulates neural crest migration during embryonic development
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Citation:
Biochem Biophys Res Comm. 2020;[Epub ahead of print] doi:10.1016/j.bbrc.2020.05.009 Epub:
Yes Abstract:
Dachshund 1(Dach1) is a key component of the retinal determination gene network that plays significant roles in cell fate... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Kim Y-K, Lee H, Ismail T, Kim Y, Lee H-S. Dach1 regulates neural crest migration during embryonic development. Biochem Biophys Res Comm. 2020;[Epub ahead of print] doi:10.1016/j.bbrc.2020.05.009. |
Neuroprotective Brain-Derived Neurotrophic Factor signaling in the TAU-P301L tauopathy zebrafish model
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Citation:
Pharmacol Res. 2020 May 14:104865. doi: 10.1016/j.phrs.2020.104865. [Epub ahead of print] Epub:
Yes Abstract:
Brain-derived neurotrophic factor (BDNF) dysregulations contribute to the neurotoxicity in neurodegenerative pathologies and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Barbereau C, Yehya A, Silhol M, Cubedo N, Verdier JM, Maurice T, Rossel M. Neuroprotective Brain-Derived Neurotrophic Factor signaling in the TAU-P301L tauopathy zebrafish model. Pharmacol Res. 2020 May 14:104865. doi: 10.1016/j.phrs.2020.104865. [Epub ahead of print]. |
Dermomyotome-derived endothelial cells migrate to the dorsal aorta to support hematopoietic stem cell emergence
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.14.096305 Epub:
Not Epub Abstract:
Development of the dorsal aorta is a key step in the establishment of the adult blood-forming system, since hematopoietic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Traver D, Sahai P, Pouget C, Svoboda O. Dermomyotome-derived endothelial cells migrate to the dorsal aorta to support hematopoietic stem cell emergence. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.14.096305. |
Antisense oligonucleotide-mediated correction of CFTR splicing improves chloride secretion in cystic fibrosis patient-derived bronchial epithelial cells
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.12.089417 Epub:
Not Epub Abstract:
Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in the CF transmembrane conductance regulator (CFTR... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: lymphoblast cell lines, hBE cells Citation Extract: Michaels WE, Bridges RJ, Hastings ML. Antisense oligonucleotide-mediated correction of CFTR splicing improves chloride secretion in cystic fibrosis patient-derived bronchial epithelial cells. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.12.089417 . |