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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Changes in retinoic acid signaling alter otic patterning
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Citation:
Development. 2007 Jul;134(13):2449-58. Epub 2007 May 23. Epub:
Not Epub Abstract:
Retinoic acid (RA) has pleiotropic functions during embryogenesis. In zebrafish, increasing or blocking RA signaling results in... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Hans S, Westerfield M. Changes in retinoic acid signaling alter otic patterning. Development. 2007 Jul;134(13):2449-58. Epub 2007 May 23.. |
Characterization of the heme synthesis enzyme coproporphyrinogen oxidase (CPO) in zebrafish erythrogenesis
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Citation:
Genes Cells. 2006 Mar;11(3):293-303 Epub:
Not Epub Abstract:
Hemoglobin consists of heme and globin proteins and is essential for oxygen transport in all vertebrates. Although biochemical... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Hanaoka R, Katayama S, Dawid IB, Kawahara A. Characterization of the heme synthesis enzyme coproporphyrinogen oxidase (CPO) in zebrafish erythrogenesis. Genes Cells. 2006 Mar;11(3):293-303. |
COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness
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Citation:
J. Clin. Invest. 2011;[Epub ahead of print] doi:10.1172/JCI45693 Epub:
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Steroid-resistant nephrotic syndrome (SRNS) is a frequent cause of end-stage renal failure. Identification of single-gene... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Heeringa SF, Chernin G, Chaki M, Zhou W, Sloan AJ, Ji Z, Xie LX, Salviati L, Hurd TW, Vega-Warner V, Killen PD, Raphael Y, Ashraf S, Ovunc B, Schoeb DS, McLaughlin HM, Airik R, Vlangos CN, Gbadegesin R, Hinkes B, Saisawat P, Trevisson E, Doimo M, Casarin A, Pertegato V, Giorgi G, Prokisch H, Rötig A, Nürnberg G, Becker C, Wang S, Ozaltin F, Topaloglu R, Bakkaloglu A, Bakkaloglu SA, Müller D, Beissert A, Mir S, Berdeli A, Özen S, Zenker M, Matejas V, Santos-Ocaña C, Navas P, Kusakabe T, Kispert A, Akman S, Soliman NA, Krick S, Mundel P, Reiser J, Nürnberg P, Clarke CF, Wiggins RC, Faul C, Hildebrandt F. COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. J. Clin. Invest. 2011;[Epub ahead of print] doi:10.1172/JCI45693. |
Crucial function of vertebrate glutaredoxin 3 (PICOT) in iron homeostasis and hemoglobin maturation
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Citation:
Mol Biol Cell. 2013 Jun;24(12):1895-903. doi: 10.1091/mbc.E12-09-0648. Epub 2013 Apr 24 Epub:
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The mechanisms by which eukaryotic cells handle and distribute the essential micronutrient iron within the cytosol and other... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Haunhorst P, Hanschmann EM, Bräutigam L, Stehling O, Hoffmann B, Mühlenhoff U, Lill R, Berndt C, Lillig CH. Crucial function of vertebrate glutaredoxin 3 (PICOT) in iron homeostasis and hemoglobin maturation. Mol Biol Cell. 2013 Jun;24(12):1895-903. doi: 10.1091/mbc.E12-09-0648. Epub 2013 Apr 24. |
Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development
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Citation:
Development. 2007 Jan;134(1):177-87 Epub:
Not Epub Abstract:
Retinoic acid (RA) is essential for normal vertebrate development, including the patterning of the central nervous system.... Organism or Cell Type:
zebrafish Citation Extract: Hernandez RE, Putzke AP, Myers JP, Margaretha L, Moens CB. Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development. Development. 2007 Jan;134(1):177-87. |
Deficient Zebrafish Ether-a-Go-Go-Related Gene Channel Gating Causes Short-QT Syndrome in Zebrafish Reggae Mutants.
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Citation:
Circulation, 2008 Feb 19;117(7):866-75. Epub 2008 Feb 4. Epub:
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BACKGROUND: -Genetic predisposition is believed to be responsible for most clinically significant arrhythmias; however,... Organism or Cell Type:
zebrafish Citation Extract: Hassel D, Scholz EP, Trano N, Friedrich O, Just S, Meder B, Weiss DL, Zitron E, Marquart S, Vogel B, Karle CA, Seemann G, Fishman MC, Katus HA, Rottbauer W. Deficient Zebrafish Ether-a-Go-Go-Related Gene Channel Gating Causes Short-QT Syndrome in Zebrafish Reggae Mutants. . Circulation, 2008 Feb 19;117(7):866-75. Epub 2008 Feb 4.. |
Determination of Endothelial Stalk versus Tip Cell Potential during Angiogenesis by H2.0-like Homeobox-1
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Citation:
Curr Biol. 2012 Oct 9;22(19):1789-94. doi: 10.1016/j.cub.2012.07.037. Epub 2012 Aug 23 Epub:
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Tissue branching morphogenesis requires the hierarchical organization of sprouting cells into leading \"tip\" and... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Herbert SP, Cheung JY, Stainier DY. Determination of Endothelial Stalk versus Tip Cell Potential during Angiogenesis by H2.0-like Homeobox-1. Curr Biol. 2012 Oct 9;22(19):1789-94. doi: 10.1016/j.cub.2012.07.037. Epub 2012 Aug 23. |
Development of an efficient method for phosphorodiamidate bond formation by using inorganic salts
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Citation:
Bioorg Med Chem Lett. 2011;[Epub ahead of print] doi:10.1016/j.bmcl.2011.12.021 Epub:
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Phosphorodiamidate morpholino oligonucleotides (PMOs) have been extensively applied in antisense strategies for gene regulation... Citation Extract: Harakawa T, Tsunoda H, Ohkubo A, Seio K, Sekine M. Development of an efficient method for phosphorodiamidate bond formation by using inorganic salts. Bioorg Med Chem Lett. 2011;[Epub ahead of print] doi:10.1016/j.bmcl.2011.12.021. |
Differential Role of PTEN Phosphatase in Chemotactic Growth Cone Guidance
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Citation:
J Biol Chem. 2013 Jun 17. [Epub ahead of print] Epub:
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Negatively targeting the tumor suppressor and phosphoinositide phosphatase PTEN promotes axon re-growth after injury. How PTEN... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Henle SJ, Carlstrom LP, Cheever TR, Henley JR. Differential Role of PTEN Phosphatase in Chemotactic Growth Cone Guidance. J Biol Chem. 2013 Jun 17. [Epub ahead of print]. |
Disruption of Esrom and Ryk identifies the roof plate boundary as an intermediate target for commissure formation
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Citation:
Mol Cell Neurosci. 2008 Feb;37(2):271-83. Epub 2007 Oct 16. Epub:
Not Epub Abstract:
Growth cones are guided to their final destination by intermediate targets. Here, we identify intermediate targets and... Organism or Cell Type:
zebrafish Citation Extract: Hendricks M, Mathuru AS, Wang H, Silander O, Kee MZ, Jesuthasan S. Disruption of Esrom and Ryk identifies the roof plate boundary as an intermediate target for commissure formation. Mol Cell Neurosci. 2008 Feb;37(2):271-83. Epub 2007 Oct 16.. |