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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Mutations in zebrafish leucine-rich repeat-containing six-like affect cilia motility and result in pronephric cysts, but have variable effects on left-right patterning

Authors:
Serluca FC, Xu B, Okabe N, Baker K, Lin SY, Sullivan-Brown J, Konieczkowski DJ, Jaffe KM, Bradner JM, Fishman MC, Burdine RD
Citation:
Development. 2009 May;136(10):1621-31
Epub:
Not Epub
Abstract:
Cilia defects have been implicated in a variety of human diseases and genetic disorders, but how cilia motility contributes to...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Serluca FC, Xu B, Okabe N, Baker K, Lin SY, Sullivan-Brown J, Konieczkowski DJ, Jaffe KM, Bradner JM, Fishman MC, Burdine RD. Mutations in zebrafish leucine-rich repeat-containing six-like affect cilia motility and result in pronephric cysts, but have variable effects on left-right patterning. Development. 2009 May;136(10):1621-31.

Myozap, a novel intercalated disc protein, activates serum response factor-dependent signaling and is required to maintain cardiac function in vivo

Authors:
Seeger TS, Frank D, Rohr C, Will R, Just S, Grund C, Lyon R, Luedde M, Koegl M, Sheikh F, Rottbauer W, Franke WW, Katus HA, Olson EN, Frey N
Citation:
Circ Res. 2010 Mar 19;106(5):880-90. Epub 2010 Jan 21
Epub:
Not Epub
Abstract:
Rationale The intercalated disc (ID) is a highly specialized cell-cell contact structure that ensures mechanical and electrical...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Seeger TS, Frank D, Rohr C, Will R, Just S, Grund C, Lyon R, Luedde M, Koegl M, Sheikh F, Rottbauer W, Franke WW, Katus HA, Olson EN, Frey N. Myozap, a novel intercalated disc protein, activates serum response factor-dependent signaling and is required to maintain cardiac function in vivo. Circ Res. 2010 Mar 19;106(5):880-90. Epub 2010 Jan 21.

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

Authors:
Sheedy FJ, Palsson-McDermott E, Hennessy EJ, Martin C, O'Leary J, Ruan Q, Johnson DP, Chen Y, O'Neill LA
Citation:
Nat Immunol. 2009 Nov 29. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The tumor suppressor PDCD4 is a proinflammatory protein that promotes activation of the transcription factor NF-kappaB and...
Delivery Method:
Lipofectamine
Organism or Cell Type:
cell culture: RAW 264.7 cells
Citation Extract:
Sheedy FJ, Palsson-McDermott E, Hennessy EJ, Martin C, O'Leary J, Ruan Q, Johnson DP, Chen Y, O'Neill LA. Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21. Nat Immunol. 2009 Nov 29. [Epub ahead of print].

Negative regulation of wnt11 expression by Jnk signaling during zebrafish gastrulation

Authors:
Seo J, Asaoka Y, Nagai Y, Hirayama J, Yamasaki T, Namae M, Ohata S, Shimizu N, Negishi T, Kitagawa D, Kondoh H, Furutani-Seiki M, Penninger JM, Katada T, Nishina H
Citation:
J Cell Biochem. 2010 Jul 1;110(4):1022-37. doi: 10.1002/jcb.22616.
Epub:
Not Epub
Abstract:
Stress-induced Sapk/Jnk signaling is involved in cell survival and apoptosis. Recent studies have increased our understanding...
Organism or Cell Type:
zebrafish
Citation Extract:
Seo J, Asaoka Y, Nagai Y, Hirayama J, Yamasaki T, Namae M, Ohata S, Shimizu N, Negishi T, Kitagawa D, Kondoh H, Furutani-Seiki M, Penninger JM, Katada T, Nishina H. Negative regulation of wnt11 expression by Jnk signaling during zebrafish gastrulation. J Cell Biochem. 2010 Jul 1;110(4):1022-37. doi: 10.1002/jcb.22616. .

Neural activity regulates synaptic properties and dendritic structure in vivo through calcineurin/NFAT signaling

Authors:
Schwartz N, Schohl A, Ruthazer ES
Citation:
Neuron. 2009 Jun 11;62(5):655-69
Epub:
Not Epub
Abstract:
The calcium-regulated protein phosphatase Calcineurin (CaN) participates in synaptic plasticity and the regulation of...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Schwartz N, Schohl A, Ruthazer ES. Neural activity regulates synaptic properties and dendritic structure in vivo through calcineurin/NFAT signaling. Neuron. 2009 Jun 11;62(5):655-69.

Non-SMC condensin I complex proteins control chromosome segregation and survival of proliferating cells in the zebrafish neural retina

Authors:
Seipold S, Priller FC, Goldsmith P, Harris WA, Baier H, Abdelilah-Seyfried S
Citation:
BMC Dev Biol. 2009 Jul 8;9(1):40. [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: The condensation of chromosomes and correct sister chromatid segregation during cell division is an...
Organism or Cell Type:
zebrafish
Citation Extract:
Seipold S, Priller FC, Goldsmith P, Harris WA, Baier H, Abdelilah-Seyfried S. Non-SMC condensin I complex proteins control chromosome segregation and survival of proliferating cells in the zebrafish neural retina. BMC Dev Biol. 2009 Jul 8;9(1):40. [Epub ahead of print].

Optogenetic localization and genetic perturbation of saccade-generating neurons in zebrafish

Authors:
Schoonheim PJ, Arrenberg AB, Del Bene F, Baier H
Citation:
J Neurosci. 2010 May 19;30(20):7111-20
Epub:
Not Epub
Abstract:
The optokinetic response (OKR) to a visual stimulus moving at constant velocity consists of a series of two alternating...
Organism or Cell Type:
zebrafish
Citation Extract:
Schoonheim PJ, Arrenberg AB, Del Bene F, Baier H. Optogenetic localization and genetic perturbation of saccade-generating neurons in zebrafish. J Neurosci. 2010 May 19;30(20):7111-20.

Otx1l, Otx2 and Irx1b establish and position the ZLI in the diencephalon

Authors:
Scholpp S, Foucher I, Staudt N, Peukert D, Lumsden A, Houart C
Citation:
Development. 2007 Sep;134(17):3167-76. Epub 2007 Aug 1
Epub:
Not Epub
Abstract:
The thalamic complex is the major sensory relay station in the vertebrate brain and comprises three developmental subregions:...
Citation Extract:
Scholpp S, Foucher I, Staudt N, Peukert D, Lumsden A, Houart C. Otx1l, Otx2 and Irx1b establish and position the ZLI in the diencephalon. Development. 2007 Sep;134(17):3167-76. Epub 2007 Aug 1.

Pax6 Regulates Gene Expression in the Vertebrate Lens through miR-204

Authors:
Shaham O, Gueta K, Mor E, Oren-Giladi P, Grinberg D, Xie Q, Cvekl A, Shomron N, Davis N, Keydar-Prizant M, Raviv S, Pasmanik-Chor M, Bell RE, Levy C, Avellino R, Banfi S, Conte I, Ashery-Padan R
Citation:
PLoS Genet. 2013;9(3):e1003357. doi:10.1371/journal.pgen.1003357
Epub:
Not Epub
Abstract:
During development, tissue-specific transcription factors regulate both protein-coding and non-coding genes to control...
Delivery Method:
Microinjection
Organism or Cell Type:
medaka embryos
Citation Extract:
Shaham O, Gueta K, Mor E, Oren-Giladi P, Grinberg D, Xie Q, Cvekl A, Shomron N, Davis N, Keydar-Prizant M, Raviv S, Pasmanik-Chor M, Bell RE, Levy C, Avellino R, Banfi S, Conte I, Ashery-Padan R. Pax6 Regulates Gene Expression in the Vertebrate Lens through miR-204. PLoS Genet. 2013;9(3):e1003357. doi:10.1371/journal.pgen.1003357.

Physiological Characterization of Muscle Strength With Variable Levels of Dystrophin Restoration in mdx Mice Following Local Antisense Therapy

Authors:
Sharp PS, Bye-A-Jee H, Wells DJ
Citation:
Mol Ther. 2010 Oct 5. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Antisense-induced exon skipping can restore the open reading frame, and thus correct the dystrophin deficiency that causes...
Delivery Method:
in vivo: intramuscular injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Sharp PS, Bye-A-Jee H, Wells DJ. Physiological Characterization of Muscle Strength With Variable Levels of Dystrophin Restoration in mdx Mice Following Local Antisense Therapy. Mol Ther. 2010 Oct 5. [Epub ahead of print].

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